Trial Information

Summary: Parkinson’s Disease with Motor Fluctuations - Adults

People with Parkinson’s disease with motor fluctuations are asked to participate in a research study being conducted by Enrico A. Fazzini, DO, PhD.

You may be eligible to participate in this study if you:

• Are at least 30 years of age or older
• Have been diagnosed with Parkinson’s disease (PD) and motor fluctuations
• Have been on stable treatment with L-dopa for at least 28 days

• You may not participate in this study if you:

  • Have severely impaired movements during the waking day
  • Have had an unclear diagnosis or a suspicion that other parkinsonian syndromes exists, such as secondary parkinsonism (caused by drugs, toxins, infectious agents, vascular disease, trauma, brain neoplasm), Parkinson-plus syndromes (e.g., multiple system atrophy, progressive supranuclear palsy) or heredodegenerative diseases
  • Have had surgery for PD or any other brain surgery
  • Have had previous treatment with dopamine agonists and it needed to be terminated within the last year because of it brought on hallucinations, psychosis, intolerable somnolence, impulse control disorder and/or any other side effect that has led to discontinuation
  • Are currently diagnosed or have a history of drug and alcohol abuse
  • Have a history of hallucinations, psychosis and/or treatment with antipsychotics for any indication within a year
  • Have seizure disorder or are taking treatments with anti-convulsants for any indication
  • Have uncontrolled insulin dependent diabetes
  • Have a history of cancer or any heart conditions
  • Are pregnant, breastfeeding, or intend to become pregnant during the study
  • Have participated in another research study within the last 30 days
  
  

If you would like to learn more about participating in this study, please send an e-mail message using the form below.