Trial Information

Summary: Membranous Nephropathy Secondary to Systemic Lupus Erythematosus (SLE) - Adults

People with Systemic Lupus Erythematosus (SLE) are asked to participate in a research study being conducted by North Shore-Long Island Jewish Health System.

You may be eligible to participate in this study if you:

• Are at least 18 years of age
• Have been diagnosed with SLE
• History of positive antinuclear antibody test (The antinuclear antibody (ANA) test is a test done to look for a group of autoantibodies that attack substances found in the center (nucleus) of all cells. It is useful as a screen for many autoantibodies associated with diseases that affect the entire body (systemic diseases)
• Have been on a stable dose of oral corticosteroids (less than or equal to 20 mg/day of prednisone or equivalent) for 2 months before study day 1
• Have had no change in therapy for SLE within 2 months before study day 1

You may not participate in this study if you:

• Have diabetes mellitus
• Have evidence lupus nephritis such as active urinary sediment
• Have uncontrolled hypertension or high blood pressure
• Have only one functioning kidney
• Have evidence of unstable clinically significant disease (eg, cardiovascular, cerebrovascular, respiratory, or renal disease, or any serious disorder that currently requires a physician’s care) other than SLE
• Have a history of cancer (except skin or cervical cancer)
• Have documented viral or bacterial infection, vomiting, fever, or diarrhea) that has not completely resolved within 7 days before study day 1
• Have a history of drug or alcohol abuse
• Are pregnant, breastfeeding, or intend to become pregnant during the study
• Have participated in another research study within the last 30 days

If you would like to learn more about participating in this study, please send an e-mail message using the form below.