Site Landscape Shrinking, Losing Most Active PIs

By CenterWatch
Published: January 2012

The investigative site landscape has become more unstable during the past five years as the number of veteran investigators, who comprise the backbone of clinical research in the United States, has shrunk at a faster rate than other segments, according to CenterWatch analysis. The analysis, which takes an in-depth look at data amassed in the FDA’s Bioresearch Monitoring Information System (BMIS) database, suggests that investigators, particularly the experienced PIs who support substantial clinical research infrastructures and incur high fixed costs, are finding it difficult to stay in business.

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