Pharmacology Research Institute (PRI) is an independent scientific research organization which began to conduct clinical studies for both domestic and foreign pharmaceutical companies in 1975. Referrals to the Institute's four offices are made by private medical/mental health professionals, agencies, health care facilities, family members, friends, or by the individuals themselves. All of PRI's services are provided AT NO CHARGE to the public.

PRI's Mission Statement:

To provide the highest quality of service for the well being of our patients in an environment that provides professional, courteous and friendly service.

To advance knowledge in the area of pharmaceutical medicine, conducting scientifically valid and reliable research studies that contribute to the maintenance and improvement in one's health and quality of life.

To maintain an environment where teamwork and camaraderie flourish, enabling us to be productive and professional in an enjoyable atmosphere.

To promote a spirit of collaboration and involvement that encourages scientific inquiry, productivity, pride and professional development.

PRI has been involved in clinical research since the 1970s. We focus on research phases II, IIB, III, III-B, and IV.

Our staff is experienced in psychiatry, neurology, ophthalmology, rheumatology, family practice, and gerontology.

We have worked previously with the following sponsors:

A.H. Robins Co. Abbott AKZO-NOBLE Alcon Angelini Astra Merck Astra USA Ayerst Bayer Beecham Pharmaceuticals Berlex Boehringer-Ingelheim Boots Pharmaceuticals Bristol-Myers Squibb Burroughs-Wellcome Ciba-Geigy, Inc. CoCensys, Inc. E.R. Squibb Eisai, Inc. Elan Pharmaceuticals Eli Lilly Forest Laboratories G.D. Searle & Co. Glaxo GlaxoWellcome H. Lundbeck Hoechst-Roussel Hoechst Marion Roussel Hoffman-LaRoche ICI America, Inc. Innapharma, Inc. Ives Laboratories Janssen Research Foundation Kali-Duphar Knoll Pharmaceuticals, Inc. Lederle, Inc.

Lipha Pharmaceuticals Lorex Pharmaceuticals McNeil Laboratories Mead-Johnson Pharmaceuticals Merck & Co. Merrel-Dow NeuroSearch, Inc. Novartis Organon, Inc. Ortho Pharmaceuticals Otsuka America Parke-Davis Pfizer, Inc. Pharmacia-Upjohn Purdue-Frederick R.W. Johnson, Co. Reckitt & Colman Reid-Rowell Rhone Poulenc Rorer Roerig, Inc. Rorer Central Research Sanofi Research Sanofi - Synthlabo SmithKline Beecham Solvay Somerset Stuart Takeda America TAP Pharmaceuticals UCB Upjohn Co. Vinoxen Company Warner-Lambert Whitehall Laboratories Yamanouchi U.S.A., Inc. Zeneca

PRI has internationally recognized expertise in pharmacological and multi-dimensional research. Diagnostic categories treated include depression, anxiety, diabetes, insomnia, migraine headaches, mild cognitive impairment, panic disorder, post-traumatic stress disorder, and Alzheimer's Disease. We have outpatient clinics in Newport Beach, Northridge, Riverside and Los Alamitos, making PRI easily accessible to persons in Orange County, Los Angeles County, including the San Fernando Valley, San Bernardino County and Riverside County.

Jon F. Heiser, M.D.
Areas of Expertise: CNS/Neurological Research

Daniel E. Grosz, M.D.
Areas of Expertise: CNS/Neurology/Children & Adolescents

Robert D. Linden, M.D.
Areas of Expertise: CNS/Behavioral Research

Charles S. Wilcox, Ph.D.
Areas of Expertise: CNS/PK + Phases I-IV

Don F. DeFrancisco, M.D., Ph.D.
Areas of Expertise: CNS/Neurological Research

The clinical staff expertise and experience at PRI is unparalleled! Working closely with our team of Board Certified physicians, we have ten masters degreed RNs with an average experience level of more than fifteen years. Our two Senior Clinical Research Coordinators, Barbara B. Katz, R.N., C.C.R.C. and Judy L. Morrissey, R.N., M.S.N., have nearly 40 years of combined clinical research experience. PRI's utilization of a clinical team concept, whereby our physicians work together with our Masters Degreed Nurse Practitioners, Clinical Nurse Specialists and Clinical Research Coordinators, enables the Institute to provide the most optimal, yet appropriate, research experience for all of our study participants. Moreover, the reliability and validity of data generated by the PRI research team is consistently categorized as being of the utmost quality.

In an era when so many organizations are scaling down on the education and experience levels required in order to work in research, PRI has held steadfast to its core values and competencies. We believe that our adherence to these high standards uniquely and consistently positions us to provide both our program participants and our grant sponsors with the best research experience possible! We thank you for your time and consideration.

PRI's offices are conveniently and strategically located in the San Fernando Valley (population of 1.7 million), the Los Angeles Harbor area (population of 3.3 million), the Orange County area (population of 2.8 million) and the Riverside-San Bernardino Counties (combined population of 3.3 million). Each population base is demographically distinct, ranging from 22% to 64% non-white in race. Similar diversity in age, education, language, and income can also be targeted for special studies.

Our Commitment to Quality Research:

Beginning in the 1970s, PRI has consistently maintained a team-oriented working environment which we believe is very conducive to providing the most optimal treatment for our study participants. The board-certified physicians and masters level nurse practitioners at PRI not only possess outstanding clinical expertise, they also consistently convey qualities that are truly exemplary of a "caring" health care provider. Our well-educated and highly-experienced team members are dedicated to providing the best care possible to the patients and communities that we serve.

PRI's outpatient clinics are located at the following addresses:

1601 Dove St., Suite 290
Newport Beach, CA 92660
Phone: 949-752-7910
Fax: 949-752-1412

8435 Reseda Blvd.
Northridge, CA 91324
Phone: 818-349-4311
Fax: 818-349-4971

3576 Arlington Avenue, Suite 301
Riverside, CA 92506-3988
Phone: 909-778-9600
Fax: 909-778-2533

4281 Katella Avenue, Suite 115
Los Alamitos, CA 90720
Phone: 714-827-3667
Fax: 714-827-3669

For the location nearest you, please call us toll-free (in California) at 1-888-PRI-HOPE.

CenterWatch is listing the following trials that are actively recruiting patients at this center.

• Adult & Geriatric Depression
• Have you thought about quitting smoking? Are you motivated to stop smoking? Volunteers are needed for a clinical trial on a new investigational medication.
• Memory Loss
• Social Phobia
• Studies involving research medications for the treatment of anxiety disorders.
• Studies with investigational antidepressant medications for men and women 18 years and older.
• Study of an investigational medication for the treatment of Alzheimer's Disease
• Study of an investigational medication for the treatment of migraine headaches
• Study of an investigational medication for the treatment of migraine headaches

For more information, please contact:

Charles S. Wilcox, Ph.D.
Executive Director
Pharmacology Research Institute, Newport Beach
1601 Dove Street, Suite 290
Newport Beach, CA 92660 USA
Phone: 949-752-7910
Fax: 949-752-1412
E-mail:

If you are interested in contacting this center to discuss placing a clinical trial there, please complete and send the E-mail form below. A representative from the research center will then follow up with you.

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Last updated on February 25, 2008

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