River Birch Research Alliance, LLC was established in 1992 by Dr. Raymond E. Tidman, MD. Our company collaborates with leading companies of the pharmaceutical industry in the investigation of new drugs and medications through clinical trials studies.

Over the years, River Birch Research has developed a reputation of excellence and trust by exceeding all enrollment goals and by completing the highest quality of work in investigational medical studies in the areas of: cardiovascular, gastroenterology, endocrinology, musculoskeletal, infectious diseases, rheumatology and dermatology. In particular, River Birch Research is a magnet for studies in COPD, osteoporosis, rheumatoid and osteoarthritis, pain and chronic pain management, bronchitis, pneumonia, hypertension, hyperlipidemia, and skin infections.

With the expansion of our physician team, we aim to bring new studies that benefit our growing patient community in areas of women%92s health, sports medicine, depression and anxiety, and hormone deficiencies.

Located "on the hill" at Riverstone Medical Campus -- a multi-specialty group clinic -- off GA 515 (www.riverstonemd.com), our success is driven primarily by the quality of care offered to our patients by our physicians, clinical and nursing staff. We welcome you to come and visit us, and learn with us, as we strive to bring better health to the greater north Georgia community.

Therapeutic areas:

• COPD
• Asthma
• Obesity
• Diabetes
• Osteoporosis
• Osteo- and rheumatoid arthritis
• Pneumonia
• Bronchitis (acute, chronic)
• Hypertension
• Hyperlipid
• Depression
• Anxiety
• Hormone deficiency
• Psoriasis
• Skin infections
• Other infectious diseases

CROs:

Quintiles, ICON, Innovex, PPD, iNC Research, Paragon, Sanofi, Ingenix Pharm, Scirex, Parexel, Omnicare, Global, etc...

For list of sponsors and years of experience:

Indication	Sponsor	Drug	Year
Pneumonia	Rhone-Poulenc Rorer	Sparfloxacin	1994
Chronic Bronchitis	Rhone-Poulenc Rorer	Sparfloxacin	1994
Hypertension with LVH	Merck & Co.	Losartan	1994
Hypertension	Sanko	Tempocapril HCL	1994
Chronic Bronchitis	Rhone-Poulenc Rorer	Sparfloxacin	1996
Pneumonia	Rhone-Poulenc Rorer	Sparfloxacin	1996
COPD	Dey Labs	Ipratropium	1996
H-Pylori	Astra+Merck	Omeprazole	1996
Hypertension	Bristol-Myers	Irbesartan	1997
COPD	SmithKline	SB207499	1997
Heartburn	TAP Holdings, Inc.	Lansoprazole	1997
Summer Flu	ViroPharma	Pleconaril	1997
Type II Diabetes	SmithKline	BRL49653C	1997
Dyspepsia	TAP Holdings, Inc.	Lansoprazole	1997
Post-MI	Proctor & Gamble	Azimilide	1997
GERD	TAP Holdings, Inc.	EM574	1997
Catheter-related Bacteremia	Rhone-Poulenc Rorer	Synercid	1997
Chronic Bronchitis	TAP Holdings, Inc.	Cefditoren	1998
Summer Flu	ViroPharma	Pleconaril	1998
COPD	SmithKline	Ariflo	1998
Pneumonia	TAP Holdings, Inc.	Cefditoren	1998
Chronic Bronchitis	SmithKline	SB265805	1999
Pneumonia	SmithKline	SB265805	1999
Chronic Bronchitis	Bristol-Myers	Cefprozil	1999
COPD	Glaxo Wellcome	Salmeterol	1999
COPD	Pfizer	CJ-13,610	1999
Pneumonia	Abbott	ABT-773	1999
Chronic Bronchitis	SmithKline	SB265805	1999
Osteoarthritis	Merck & Co.	Rofecoxib	2000
Drug Na%EFve Diabetes	SmithKline	Rosiglitazone	2000
Irritable Bowel Syndrome	Glaxo Wellcome	Alosetron	2000
DNA-Healthy Subjects	Genomics	-	2000
DNA-Diseased Subjects	Genomics	-	2000
In-Patient Pneumonia	Bayer	BAY 12-8039	2000
Impetigo	PharmaKinetics	Mupirocin 2%	2000
Soft Tissue Infection	Cubist Pharmaceuticals	Daptomycin	2000
Hypertension	PPD Development	Omapatrilat	2000
COPD	SmithKline	Ariflo	2001
Migraine Headache	Astrazeneca	-	2001
Pneumonia	Bayer	Faropenem	2001
Pneumonia	Cubist Pharmaceuticals, Inc	Cidecin	2001
COPD	SmithKline	Ariflo	2001
Sinusitis	Warner-Lambert	Sudafed	2001
Pneumonia	Aventis	Telithromycin	2001
Chronic Bronchitis	SmithKline	Augumentin	2001
Skin+Skin Structure Infection	Eli Lilly	Oritavancin	2001
Irritable Bowel Syndrome	Solvay	Celansetron	2002
COPD	Abgenix	ABX-IL8	2002
Nursing Home Depression	Organon	Remeron	2002
Asthma	Aventis	Ciclesonide	2002
Pressure Ulcer	Smith & Nephew	Santyl	2002
Sinusitis	Advanced Biologics	Levaquin	2002
Hyperlipidemia	Sanofi-Synthelabo	Plavix	2002
Hypertension	Bertek	Nebivolol	2002
GERD	PPD Development	Lansoprazole	2002
Type II Diabetes	Astrazeneca	AZ-242	2002
Chronic Bronchitis	GlaxoSmithKline	Augmentin SR	2002
COPD	GlaxoSmithKline	Seretide+Viani+Advair	2002
Rheumatoid Arthritis	Bristol-Myers Squibb	BMS-188667	2002
Pediatric Pneumonia	Johnson & Johnson	Levaquin	2002
Pediatric Otitis Media	Johnson & Johnson	Levaquin	2002
Laparoscopic Cholecystectomy	Pharmacia	Valdecoxib	2002
Chronic Bronchitis	Paragon Biomedical	Clarithromycin ER	2002
HTN with Hyperlipidemia	Pfizer	Amlodipine & Atorvastatin	2002
Gout	Pharmacia	Valdecoxib	2002
Cardiac Event Prevention	Astrazeneca	Avandia	2002
Type II Diabetes with Insulin	Parexel	Avandia	2002
Hypertension	Sanofi-Synthelabo	Avalide	2003
Migraine Headache	Pfizer	Relpax	2003
Psoriasis	Genentech, Inc.	Raptiva	2003
Type II Diabetes	GlaxoSmithKline	Avandia	2003
COPD	Centocor	Remicade	2003
Irritable Bowel Syndrome	GlaxoSmithKline	Lotronex	2003
Depression	Eli Lilly	Duloxetine	2003
Osteoarthritis of Knee & Hip	Grunenthal, Inc.	-	2004
COPD	ALTANA Pharma, Inc.	Roflumilast	2003
Post-Stroke	Aventis	Lovenox	2003
Chronic Bronchitis	Abbott	Biaxin	2003
Medabolic Syndrome	Sanofi-Synthelabo	Plavix	2003
CAD Prevention	Astrazeneca	-	2003
Hypertension	Integrium	Micardis	2003
Asthma	PPD Development	-	2003
Type II Diabetes	GlaxoSmithKline	Avandia	2003
Migraine Headache	Access Medical	Maxalt	2003
COPD	Dey Labs	-	2004
Benign Prostatic Hypertrophy	i3 Research	-	2004
Skin Infection	Basilea	-	2004
Gout	Pfizer	Valdecoxib	2004
Osteoporosis	Eli Lilly	Arzoxifene	2004
Osteoarthritis	Alza	Hydromorphone HCL	2004
Type II Diabetes	Takeda	TAK-559	2004
Psoriasis	Genentech, Inc.	Raptiva	2005
Osteoarthritis	Johnson & Johnson	CG5503	2005
COPD	Centocor	Remicade	2004
Elevated CRP	PPD Development	Crestor	2004
Otitis Media	Sanofi-Aventis	Telithromycin	2005
Metabolic Syndrome	Bristol-Myers Squibb	Plavix	2005
Chronic Bronchitis	Replidyne, Inc.	Faropenem	2005
Hypertension	Alteon	Alagebrium	2005
Type II Diabetes	Roche	RO0730699	2005
Pneumonia	Advanced Life Sciences	Clarithromycin	2006
COPD	ALTANA Pharma, Inc.	Roflumilast	2006
Hypertension	Boehringer Ingelheim	Micardis	2006
Atrial Fibrillation	Sanofi-Aventis	Dronedarone	2006
Atrial Fibrillation	Boehringer Ingelheim	Dabigatran	2006
Heartburn on NSAIDS	Pfizer	Celecoxib	2006
Heartburn	PPD	Prevacid	2007
Osteoarthritis of Knee & Hip	Alpharma Pharmaceuticals	Extended-Release Kadian	2007
Chronic Pain	Alpharma Pharmaceuticals	Extended-Release Kadian	2007

River Birch Research Alliance, LLC is located within the Riverstone MD PC medical campus. Riverstone MD PC is a multi-specialty clinic with in house specialty clinic, walk-in clinic, pharmacy, radiology, dentist, physical therapists, sports medicine, internal medicine, pediatrics, family practice, oncology, blood/lab services and arespiratory center. We have specialist doctors in gastroenterology, podiatry, OB/GYN, ENT, rheumatology, internal medicine/pediatrics, radiology, oncology, nephrology and dermatology We are equipped to do X-rays, MRI/CT scans, bone density, Dexa scans, and many other specialized outpatient procedures.We are located conveniently off of the Appalachian Hwy (GA-515) for easy and quick travel for patients. We have a close partnership with Fannin Regional Hospital which is equipped for Level III trauma/ER services, as well as Piedmont Mountainside Hospital in Jasper, GA. For a privately run specialty group clinic, we boast several high end equipment and services.

Dr. Raymond Tidman, MD
President and CEO, Principal Investigator, Family Practice

Dr. Kelly Koay, MD
Research Sub-investigator, Internal Medicine and Pediatrics

Dr. Jack Roof, MD
Research Sub-investigator, Family Practice

Dr. Tidman's research experience:

Indication	Sponsor	Drug	Year
Pneumonia	Rhone-Poulenc Rorer	Sparfloxacin	1994
Chronic Bronchitis	Rhone-Poulenc Rorer	Sparfloxacin	1994
Hypertension with LVH	Merck & Co.	Losartan	1994
Hypertension	Sanko	Tempocapril HCL	1994
Chronic Bronchitis	Rhone-Poulenc Rorer	Sparfloxacin	1996
Pneumonia	Rhone-Poulenc Rorer	Sparfloxacin	1996
COPD	Dey Labs	Ipratropium	1996
H-Pylori	Astra+Merck	Omeprazole	1996
Hypertension	Bristol-Myers	Irbesartan	1997
COPD	SmithKline	SB207499	1997
Heartburn	TAP Holdings, Inc.	Lansoprazole	1997
Summer Flu	ViroPharma	Pleconaril	1997
Type II Diabetes	SmithKline	BRL49653C	1997
Dyspepsia	TAP Holdings, Inc.	Lansoprazole	1997
Post-MI	Proctor & Gamble	Azimilide	1997
GERD	TAP Holdings, Inc.	EM574	1997
Catheter-related Bacteremia	Rhone-Poulenc Rorer	Synercid	1997
Chronic Bronchitis	TAP Holdings, Inc.	Cefditoren	1998
Summer Flu	ViroPharma	Pleconaril	1998
COPD	SmithKline	Ariflo	1998
Pneumonia	TAP Holdings, Inc.	Cefditoren	1998
Chronic Bronchitis	SmithKline	SB265805	1999
Pneumonia	SmithKline	SB265805	1999
Chronic Bronchitis	Bristol-Myers	Cefprozil	1999
COPD	Glaxo Wellcome	Salmeterol	1999
COPD	Pfizer	CJ-13,610	1999
Pneumonia	Abbott	ABT-773	1999
Chronic Bronchitis	SmithKline	SB265805	1999
Osteoarthritis	Merck & Co.	Rofecoxib	2000
Drug Na%EFve Diabetes	SmithKline	Rosiglitazone	2000
Irritable Bowel Syndrome	Glaxo Wellcome	Alosetron	2000
DNA-Healthy Subjects	Genomics	-	2000
DNA-Diseased Subjects	Genomics	-	2000
In-Patient Pneumonia	Bayer	BAY 12-8039	2000
Impetigo	PharmaKinetics	Mupirocin 2%	2000
Soft Tissue Infection	Cubist Pharmaceuticals	Daptomycin	2000
Hypertension	PPD Development	Omapatrilat	2000
COPD	SmithKline	Ariflo	2001
Migraine Headache	Astrazeneca	-	2001
Pneumonia	Bayer	Faropenem	2001
Pneumonia	Cubist Pharmaceuticals, Inc	Cidecin	2001
COPD	SmithKline	Ariflo	2001
Sinusitis	Warner-Lambert	Sudafed	2001
Pneumonia	Aventis	Telithromycin	2001
Chronic Bronchitis	SmithKline	Augumentin	2001
Skin+Skin Structure Infection	Eli Lilly	Oritavancin	2001
Irritable Bowel Syndrome	Solvay	Celansetron	2002
COPD	Abgenix	ABX-IL8	2002
Nursing Home Depression	Organon	Remeron	2002
Asthma	Aventis	Ciclesonide	2002
Pressure Ulcer	Smith & Nephew	Santyl	2002
Sinusitis	Advanced Biologics	Levaquin	2002
Hyperlipidemia	Sanofi-Synthelabo	Plavix	2002
Hypertension	Bertek	Nebivolol	2002
GERD	PPD Development	Lansoprazole	2002
Type II Diabetes	Astrazeneca	AZ-242	2002
Chronic Bronchitis	GlaxoSmithKline	Augmentin SR	2002
COPD	GlaxoSmithKline	Seretide+Viani+Advair	2002
Rheumatoid Arthritis	Bristol-Myers Squibb	BMS-188667	2002
Pediatric Pneumonia	Johnson & Johnson	Levaquin	2002
Pediatric Otitis Media	Johnson & Johnson	Levaquin	2002
Laparoscopic Cholecystectomy	Pharmacia	Valdecoxib	2002
Chronic Bronchitis	Paragon Biomedical	Clarithromycin ER	2002
HTN with Hyperlipidemia	Pfizer	Amlodipine & Atorvastatin	2002
Gout	Pharmacia	Valdecoxib	2002
Cardiac Event Prevention	Astrazeneca	Avandia	2002
Type II Diabetes with Insulin	Parexel	Avandia	2002
Hypertension	Sanofi-Synthelabo	Avalide	2003
Migraine Headache	Pfizer	Relpax	2003
Psoriasis	Genentech, Inc.	Raptiva	2003
Type II Diabetes	GlaxoSmithKline	Avandia	2003
COPD	Centocor	Remicade	2003
Irritable Bowel Syndrome	GlaxoSmithKline	Lotronex	2003
Depression	Eli Lilly	Duloxetine	2003
Osteoarthritis of Knee & Hip	Grunenthal, Inc.	-	2004
COPD	ALTANA Pharma, Inc.	Roflumilast	2003
Post-Stroke	Aventis	Lovenox	2003
Chronic Bronchitis	Abbott	Biaxin	2003
Medabolic Syndrome	Sanofi-Synthelabo	Plavix	2003
CAD Prevention	Astrazeneca	-	2003
Hypertension	Integrium	Micardis	2003
Asthma	PPD Development	-	2003
Type II Diabetes	GlaxoSmithKline	Avandia	2003
Migraine Headache	Access Medical	Maxalt	2003
COPD	Dey Labs	-	2004
Benign Prostatic Hypertrophy	i3 Research	-	2004
Skin Infection	Basilea	-	2004
Gout	Pfizer	Valdecoxib	2004
Osteoporosis	Eli Lilly	Arzoxifene	2004
Osteoarthritis	Alza	Hydromorphone HCL	2004
Type II Diabetes	Takeda	TAK-559	2004
Psoriasis	Genentech, Inc.	Raptiva	2005
Osteoarthritis	Johnson & Johnson	CG5503	2005
COPD	Centocor	Remicade	2004
Elevated CRP	PPD Development	Crestor	2004
Otitis Media	Sanofi-Aventis	Telithromycin	2005
Metabolic Syndrome	Bristol-Myers Squibb	Plavix	2005
Chronic Bronchitis	Replidyne, Inc.	Faropenem	2005
Hypertension	Alteon	Alagebrium	2005
Type II Diabetes	Roche	RO0730699	2005
Pneumonia	Advanced Life Sciences	Clarithromycin	2006
COPD	ALTANA Pharma, Inc.	Roflumilast	2006
Hypertension	Boehringer Ingelheim	Micardis	2006
Atrial Fibrillation	Sanofi-Aventis	Dronedarone	2006
Atrial Fibrillation	Boehringer Ingelheim	Dabigatran	2006
Heartburn on NSAIDS	Pfizer	Celecoxib	2006
Heartburn	PPD	Prevacid	2007
Osteoarthritis of Knee & Hip	Alpharma Pharmaceuticals	Extended-Release Kadian	2007
Chronic Pain	Alpharma Pharmaceuticals	Extended-Release Kadian	2007

Dr. Maxwell C. Eblaghie, PhD
Chief Research Officer
Post-Doctoral Research Fellow, Albert Eye Research Institute, Duke University, Durham, NC (2005-2007)

Post-Doctoral Research Associate, Cell Biology, Duke University, Durham, NC (2003-2005)

PhD/Post-Doctoral Research Assistant, Cell and Developmental Biology, The University of Dundee, Scotland (2000-2003)

Deborah Allen, CCRC
Study Coordinator
(10+ years clinical research experience)

Renea Yeagley, MA, CCRC
Study Coordinator
(10+ years clinical research experience)

Patient Population in Blue Ridge, GA:

• 97.5% white (caucasian)
• 0.4% Hispanic/latino
• 0.2% black
• 0.3% asian
• 1.1% multi-racial
• 0.1% other

• 50.5% female
• 49.5% male

• 10.9% 0-9 years
• 12.5% 10-19 years
• 9.4% 20-29 years
• 12.9% 30-39 years
• 15.7% 40-49 years
• 15.2% 50-59 years
• 12.3% 60-69 years
• 7.8% 70-79 years
• 3.5% 80+ years

We use Central IRB

Interested sponsors and CROs can also contact Dr. Eblaghie through an alternate email address: maxwell.eblaghie@gmail.com.

CenterWatch is listing the following trials that are actively recruiting patients at this center.

• A Multi-Center, Double-blind, Placebo-controlled, Safety and Preliminary Efficacy Study of IL-1 Trap (rilonacept) Administered Subcutaneously in Subjects with Non Dialysis-Dependent Chronic Kidney Disease (NDD-CKD) and Anemia
• A multi-center, randomized, double-blind, assessor-blind, non-inferiority study comparing the efficacy and safety of once-weekly subcutaneous biotinylated idraparinux (SSR126517E) with oral adjusted-dose warfarin in the prevention of stroke and systematic thromboembolic events in patients with atrial fibrillation.
• A Phase III, Flexible-Dose Titration Followed by a Randomized, Double-Blind Study of Controlled-Release OROS Hydromorphone HCl (NMED-1077) Compared to Placebo in Patients with Osteoarthritis Pain.
• A Randomized, Double-Blind, Parallel-Group Study to Evaluate the Safety and Efficacy of Tocilizumab (TCZ) versus Placebo in Combination with Methotrexate in Patients with Moderate to Severe Active Rheumatoid Arthritis (RA)

For more information, please contact:

Dr. Maxwell C. Eblaghie, PhD
Chief Research Officer
River Birch Research Alliance, LLC
101 Riverstone Vista, Suite 206
Blue Ridge, GA 30513 USA
Phone: 706-258-4112
Fax: 706-632-6006
E-mail:

If you are interested in contacting this center to discuss placing a clinical trial there, please complete and send the E-mail form below. A representative from the research center will then follow up with you.

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Last updated on February 25, 2008

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