Vision Statement:
Kingshill Research Centre aspires to improve 'quality of life' for patients and carers by producing high quality research information for use in the development of new treatment alternatives.

The Kingshill Research Centre:
Since it opened in 1994 as a clinical trials site, Kingshill has gained an international reputation for excellence. During this time, it has worked for more than 30 pharmaceutical companies and contract research organisations on over 35 different clinical trials. The centre also has a growing reputation as an academic research institution, conducting independent investigations focusing on comprehensive assessment in dementia.

Based in the UK, Kingshill Research Centre encompasses an NHS Charitable Trust (registered charity number 1056576) and is also an NHS department, forming part of the Avon and Western Wiltshire Mental Health Care NHS Trust. It is adjacent to and works closely with the Department of Old Age Psychiatry at the Victoria Hospital in Swindon.

Kingshill’s Director and Principal Investigator is Dr Roger Bullock, who has over 10 years clinical trials experience and is regularly consulted on the development of new trial protocols.

Kingshill uses new technology and an innovative approach to price services competitively and provide a full range of complementary services to the sponsor. These services include:

• Protocol development and consultancy
• MREC (Multi Regional Ethics Committee) applications
• Investigator recruitment
• Phase II, III, IV and post-market surveillance clinical trials.

• Alzheimer's Disease
• Vascular Dementia
• Lewy Body Dementia
• Mild Cognitive Impairment (MCI)
• Major Depressive Disorder
• Other neurological and psychiatric conditions affecting the elderly.

Kingshill and Dr Bullock have worked with a large number of sponsors including:
Astra Pharmaceuticals, Bayer, Boehringer Ingelheim Pharmaceuticals, Cromedica, Dista Products, Eisai Company, Elan Pahrmaceuticals, Eli Lilly, Glaxo Wellcome, Hoechst Marion Roussel, Ingenix, Innovex, Janssen Pharmaceuticals, Mers Pharma, Novartis, Organon, Parke-Davis, Pfizer, Pharmacia, Pharmacia and Upjohn, Protodigm, Roche Laboratories, Sandoz, Searle and Company, Shire Pharmaceuticals, SmithKline Beecham, Toyama, Quintiles and Zeneca.

Continuous Quality Assessment:
Quality is the watchword for the centre. All clinical trials team members are trained to ICH GCP standards and are members of the Institute of Clinical Research, ensuring that the standards are not only being met but exceeded.

The site has had extremely positive reviews as a result of the audits conducted by sponsors during the course of trials. It has not yet been audited by the FDA but adheres to the standards demanded by the European and US regulatory authorities.

Kingshill Research Centre is currently housed in a 2500sq ft facility located on the first floor of Victoria Hospital, Swindon. Disabled access is made possible by a lift.

The centre features:

• 3 examination rooms
• a waiting area
• offices
• a large Carers' Room (also used for training, meetings and monitor visits)
• an academic library for the use of staff at Kingshill and in the Department of Old Age Psychiatry at Victoria Hospital

Location
Kingshill Research Centre is located in the town of Swindon, ideally placed just off the M4 and an easy distance from the cities of London and Bristol.

Director and Principal Investigator Dr Roger Bullock has over 10 years clinical trials experience and is regularly consulted on the development of new trial protocols. He is also Consultant and Manager of the Old Age Psychiatry Department in the Avon and Western Wiltshire Mental Health Care NHS Trust. The research centre is on the same site as Dr Bullock’s NHS practice, allowing speedy identification of patients who may benefit from trial participation.

Dr. Bullock is well respected in his field and is often called upon to speak to professional groups about his work. He is committed to research, particularly in psychopharmacology, neuropsychology and the use of both in all areas of care. He believes that clinical trials not only benefit his current patients but will be of significant benefit to further patients in the future. He also feels that trials improve the service, introducing additional rigour to clinical practice.

Kingshill’s multi-disciplinary team includes doctors, psychiatrists, psychologists, research nurses, a GP researcher, a health policy research fellow, a clinical trials administrator, a business development officer and an information officer. In addition, through its close working relationship with the Department of Old Age Psychiatry, the Centre is able to draw on the expertise of occupational, speech and physio-therapists as well as social workers.

The staff, individually and collectively take pride in and are committed to producing data of the highest quality, understanding the need to scrupulously adhere to protocols whilst keeping the patient's best interests at heart.

Kingshill Research Centre has a population base of 30,000 elderly people. The area encompasses both rural and urban environments with a wide cultural diversity allowing the site to recruit to the most stringent trial requirements.

Recruitment is on a trial-by-trial basis and the site aims to match patients to trials for maximum benefit to both patient and sponsor. The needs of the patient, carer and study are respected, with the comfort of the patient and the success of the study as the prime objectives. In addition, the site has built a reputation for providing support to the carers enhancing patient retention and recruitment to further trials.

The relationship with the Avon and Western Wiltshire Mental Health Care NHS Trust ensures that any patients suitable for trials who come into contact with the team are referred onwards to the site. In addition, the site works closely with the local primary care teams, ensuring that the majority of those patients within the catchment area who may be suitable for particular trials are contacted.

Kingshill has a reputation for speedy recruitment of trial patients and of high retention levels. Due to a rigorous pre-screening programme, very few patients drop out after entry to a study.

For more information, visit The Kingshill Research Centre Web Site.

For more information, please contact:

Gina Dennis
Information Officer
The Kingshill Research Centre
Victoria Hospital
Okus Road
Swindon SN1 4JU United Kingdom
Phone: +44 (0) 1793-481-182
Fax: +44 (0) 1793-437-521
E-mail:

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Last updated on June 20, 2008