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Mediprobe Research |
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Center Overview
Mediprobe Research is a world class dermatology research and clinical trials center.
We provide excellent and compassionate care to our patients through modern state-of-the-art clinical trial facilities and highly trained, dedicated staff. Together with a basic research laboratory staffed with a team of skilled scientists, we are able to conduct high quality research.
Together with a basic research laboratory staffed with a team of highly skilled research scientists (6 staff: 5 Ph.D., 1 M.D.), we are able to conduct quality research in the field of antifungal therapeutics.
Mediprobe works with pharmaceutical companies to develop study designs and write study protocols, case report forms and written informed consent forms in-house. We conduct Phase II-IV clinical trials to GCP standards and meet all applicable regulatory requirements. We conduct pharmacokinetic trials and ship plasma samples for bioanalytical assay. We also offer data entry from case report forms, statistical analysis and the writing of final reports and publications.
We have a track record of publishing 20-25 research papers each year in peer-reviewed, indexed Medical Journals, in addition to presentations at major North American and European research meetings.
Mediprobe meets the demands of pharmaceutical companies to conduct their trials safely and on time. Our expertise enables us to start the projects efficiently and recruit patients quickly. Our staff is familiar with ICH-GCP guidelines. We conduct international clinical trials under Canadian and US INDs with clients from Canada, the United States and abroad. We ensure that the clinical trials are conducted according to the study protocol, the sponsor guidelines and regulatory requirements.
In 2005, Mediprobe will undertake clinical trials in other fields of medicine including hypertension, diabetes and hypercholesterolemia.
Also in 2005, Mediprobe Research will expand its operations to include a Phase I unit with a capacity of 54 beds. The new clinic will allow conducting a wide variety of clinical trials in-house where subjects can be institutionalized for days at a time. The new studies include bioequivalence trials with oral formulations and vasoconstrictive trials with topical corticosteroids.
Clinical Research Experience
- Acne
- Eczema/Atopic Dermatitis
- Actinic Keratosis
- Rosacea
- Onychomycosis
- Psoriasis
- Pustular Psoriasis
- Tinea Pedis
- Tinea Capitis
- Photoaging
- Dermatitis
- Skin Cancer
- Pharmacokinetic trials
- Melasma
Mediprobe has conducted over 75 clinical trials Phase II-IV in dermatology in children and adults.
Facility Description
Our Advantages:
- Extended weekday hours (8 a.m. - 9 p.m.) as well as Saturday appointments for patient convenience with free parking
- Central location, with easy access from Highways 401 and 402, and London Airport
- On-site dermatology research laboratory
- Dedicated photographic studio
- Specialized light therapy on site
- Experience in conducting clinical trials requiring drug administration via topical, intravenous, intramuscular, and subcutaneous routes
- On site phlebotomy with extensive expertise in processing and shipping samples
- Experience in electronic data capture and management of large data bases
- In-house protocol development and data management
Our Facility:
- A custom designed 19,000 sq. ft. clinical trials facility with a 2000 sq. ft. state-of-the-art laboratory dedicated to dermatologic research
- Conference rooms for visiting monitors with phone/fax/internet access
- Photographic studio with Canfield state-of-the-art camera systems
- Secured medical file and chart storage facilities
- Dedicated, thermostat controlled, monitored and secured drug storage facilities
- Monitored freezers (-40°C, -80°C) and fridges (0° to 8°C)
- Back-up generator
- Documentation room
Investigator Experience
Aditya K. Gupta, M.D., Ph.D., M.A.(Cantab), DABD, FAAD, FRCPC, Medical Investigator
Dr. Gupta is a board certified dermatologist who has extensive experience in conducting clinical trials. He obtained a degree in Engineering from King's College, University of Cambridge, U.K. followed by his medical degree from the University of Southampton Medical School, Southampton, U.K. He then did training in Internal Medicine at the University of Toronto, Toronto, Canada and subsequently a residency in dermatology and clinical trials fellowship from the University of Michigan, Ann Arbor, MI, USA.
Dr. Gupta went on to perform research training at the National Institutes of Health, Bethesda, MD, USA. This was followed by further research in the Department of Dermatology, University of Göteborg and Shalgrenska University Hospital, Göteborg, Sweden where he obtained a Ph.D.
Dr. Gupta is an Associate Professor, Division of Dermatology, Department of Medicine, Sunnybrook and Women's College Health Sciences Center (Sunnybrook site) and the University of Toronto, Toronto, Canada. Dr. Gupta has conducted approximately 75 Phase II, III and IV clinical trials and has been a primary investigator at Mediprobe Research Inc. for about 50 of those trials.
He has written over 400 articles and book chapters that have appeared in journals published in the US, Canada, Europe and other countries. Moreover, he is on the Editorial Board/ Advisory Board/ Section Editor of 20 journals:
- Clinics in Dermatology
- Cutis
- International Journal of Dermatology (Associate Editor)
- International Journal of Immunopathology and Pharmacology (Associate Editor)
- Journal of the American Podiatric Medical Association
- Journal of Cutaneous Medicine and Surgery
- Journal of Dermatological Treatment
- Journal of Drugs in Dermatology (Senior Editor)
- Journal of the European Academy of Dermatology & Venereology
- Medical Mycology (formerly Journal of Medical & Veterinary Mycology)
- Mikologia Lekarska (Medical Mycology)
- Mycoses
- Pediatric Dermatology
- Podiatry Today
- Practical Dermatology
- Revista Iberoamericana de Micologia
- SKINmed: Dermatology for the clinician (Section Editor)
- Skin and Aging
- Skin Therapy Letter
Dr. Gupta serves on the Dermatology Expert Committee of the United States Pharmacopoeia. He is the Treasurer and Board Member of the Council of Nail Disorders. Dr. Gupta is also on the Board of Directors of the Skin of Color Society.
Staff Expertise
Madhulika A. Gupta, M.D., FRCPC, President
Dr. Madhulika A. Gupta obtained her medical degree from the University of Toronto, Toronto, Canada and then completed a residency in Family Medicine followed by a residency in Psychiatry, both at the University of Toronto. Dr. M. A. Gupta is a Certificant of the College of Family Physicians of Canada and a Fellow of the Royal College of Physicians of Canada. She is also a Diplomate of the American Board of Psychiatry and Neurology and the American Board of Sleep Medicine.
Dr. Gupta has been the principal investigator in various studies in psychiatry and subinvestigator for several studies in dermatology. She has over 70 publications in refereed journals, has written several book chapters and presented at various national and international conferences in both psychiatry and dermatology. She regularly serves as a reviewer for medical journals in both psychiatry and dermatology.
She currently has a private practice in psychiatry and is involved in clinical research.
Jean-Maurice St-Onge, B.Sc. Pharm., M.Sc., Ph.D, Vice President, Clinical Research
Dr. St-Onge holds a Doctorate degree in Pharmacology, a Master degree in Pharmaceutical Sciences (pharmacokinetics) and a Bachelor in Pharmacy from the Universite de Montreal. After practicing pharmacy for six years, he moved to the industry where he gained more than 21 years of experience in phase I-IV clinical trials in Canada, the United States and in Europe with innovative, biotech, generic and natural health products. He has held positions in pharmaceutical and biotech companies and contract research organizations in Canada.
He has broad experience in many therapeutics areas, including oncology, gastrointestinal, anti-inflammatory, CNS, cardiovascular, respiratory, dermatology and infectious diseases. He has had strategic project management experience in bioequivalence studies with generic products at Novopharm Limited for ten years. He has also experience in the management of laboratories in research and development.
His responsibilities include the sales and marketing of clinical trials and the development and implementation of clinical research projects. Dr. St-Onge is also responsible for the extension of the operations of Mediprobe Research in bioequivalence studies in a research center in 2005.
Muhammad M. Zaman, BA (Hons), MA, Ph.D., Vice President, Analytical Research and Development
Dr. Muhammad Zaman holds a Bachelors Degree in Biochemistry, Master's Degree in Molecular Biology, Doctoral degree in Biochemistry as well as Postdoctoral Training in Infectious Diseases from Harvard University. He also held the position of a Senior Research Fellow at the Harvard School of Public Health prior to joining Mediprobe Research, Inc. in October of 2003.
He has broad experience in many areas of molecular biology including regulation of drug resistance genes in human pathogens, genetic recombination mechanisms, and enzyme purification and characterization.
His responsibilities include scientific and administrative management of the analytical research and development arm of Mediprobe Research, Inc.
Clinical Research Coordinators
The clinical team is comprised of 15 qualified clinical research coordinators with experience in the management of clinical trials in children and adults.
Patient Demographics
Our medical center has a patient pool of 750,000, covering all of Southwestern Ontario, Canada. Our clinical trials are conducted in adults and children.
For location information, please visit www.mediproberesearch. com
Other Information
To meet your clinical trial needs, we provide:
- Over 20 years experience in clinical trials
- Adherence to Good Clinical Practices (GCP), International Conference on Harmonization
- Guidelines (ICH), and regulatory guidelines in conducting clinical trials in Canada and the U.S.A.
- A track record of 15 or more ongoing studies each year over the last 6 years
- A highly trained and experienced staff of 15 professionals
- State-of-the-art equipment
- Access to a central IRB with a short turnaround time
- Expertise in conducting Quality of Life Studies and Questionnaire Design
- Data management and report writing
- Regulatory submissions
- Site management services
- Study protocols, consent forms and case report forms
- Regulatory compliance
- Quick turnaround contract negotiations
- Consultations for study designs
Contact Information
For more information, please contact:
Dr. Aditya Gupta
Medical Investigator
Mediprobe Research
645 Windermere Road
London, Ontario N5X 2P1 Canada
Phone: 519-657-4222 ext. 277 Dr. Aditya Gupta
or ext. 228 Dr. Jean-Maurice St-Onge
Fax: 519-657-4233
E-mail:
If you are interested in contacting this center to discuss placing a clinical trial there, please complete and send the E-mail form below. A representative from the research center will then follow up with you.
