Connecticut Urological REsearch at Grove Hill (CURE) was founded by Rafael Wurzel, M.D. and is part of the largest multi-specialty group in the state of Connecticut with over 80 providers, serving a diverse population in nine locations. Our physicians have large, busy practices, with a database of over 500,000 active patients and a large referral base. This enables us to exceed enrollment quotas while providing the highest quality patient care. Our experienced research staff is dedicated to coordinating clinical trials according to GCP/ICH guidelines.

CURE was founded in 1999 and our research center has seen remarkable growth since its inception. CURE attracts staff with extensive research experience and to date we have successfully completed >30 clinical trials, phases II, III, and IV. We are currently commencing Phase I trials in healthy males. We have multiple phase II-IV studies currently in progress or poised to begin in the near future. Most of our study patients are enrolled from our patient database and local referrals.

Our center has extensive experience conducting trials in the following Urologic therapeutic areas:

Men’s Health

• Erectile Dysfunction
• Premature Ejaculation
• Benign Prostatic Hyperplasia
• Hormone Replacement
• Interstitial Cystitis/Painful Bladder Syndrome
• Urinary Tract Infections
• Acute Urinary Retention
• Hypogonadism
• Prostatitis
• Sperm Assessment

• Female Sexual Dysfunction
• Interstitial Cystitis/Painful Bladder Syndrome
• Urinary Tract Infections
• Acute Urinary Retention

• Overactive Bladder
• Stress Incontinence

• Bladder Cancer
• Prostate Cancer
• Prostate Cancer Prevention

• Sperm Analysis

CURE is a centrally located facility, with convenient highway access. The nearest acute care hospital is less than 1 mile in distance. Through our association with Grove Hill Medical Center we have cross-specialty availability to a full range of medical disciplines. We will be expanding to our research facility which we expect to open in the summer of 2007.

• Patient waiting area
• 8 exam rooms
• Secure drug storage area
• Secure record storage
• Monitor work area
• Phlebotomy and specimen processing lab
• Portable ECG machine
• Autoclave
• -20° Freezer
• -70° Freezer storage
• Oxygen
• IV Fluids
• EDC capability with DSL access

• Bladder Scan
• Uroflowmeter
• Biofeedback
• Cavernosometry
• Color Doppler
• Cystoscopy
• Urodynamics
• Diagnostic Ultrasound
• Duplex Ultrasound
• Nocturnal Tuminescence monitor
• Rigiscan
• Access to Radiological services

There is a strong collaborative relationship amongst our clinical providers in support of research.

Rafael Wurzel, M.D.
Medical Director of CURE
Board Certified in Urology

Keith Kaplan, M.D.
Board Certified in Urology

Paul J. Ceplenski, M.D.
Board Certified in Urology

Corlis Archer-Goode, M.D.
Board Certified in Urology

Robert Ave’Lallemant, M.D.
Board Certified in Urology

Mansour Isckarus, M.D.
Board Certified in Hematology/Oncology

Kerry Rausch, MSN, APRN
Urology Nurse Practitioner

Lihi Brocke, Ph.D., CCRC
Clinical Research Manager
Total Experience: 8 years

Kathy Mroczka, LPN
Clinical Research Coordinator
Total Experience: 3 years

Antonina Vaverchak, LPN, CCRC
Clinical Research Coordinator
Total Experience: 12 years

Evelyn Cordero
Research Technician
Total Experience: 3 years

All staff members receive routine training in Good Clinical Practices, and FDA regulations.

We have access to a demographically diverse patient population via our half-million plus multi-specialty practice database. In addition, we utilize local advertising initiatives, and conduct community outreach to local senior centers, assisted living facilities, and community clinics.

At CURE, we have successfully worked with a variety of sponsors, cooperative research groups, and CRO’s. We ensure expeditious processing of regulatory documents, with the flexibility of using either central or local IRB.

For more information, please contact:

Lihi Brocke, PhD, CCRC
Clinical Research Manager
Connecticut Urological REsearch at Grove Hill (CURE)
One Lake Street
New Britain, CT 06052 USA
Phone: 860-826-4453 ext. 5276
Fax: 860-801-6751
E-mail:

If you are interested in contacting this center to discuss placing a clinical trial there, please complete and send the E-mail form below. A representative from the research center will then follow up with you.

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Last updated on February 19, 2008

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