Midwest Chest Consultants, PC is a private office based medical practice specializing in pulmonary, critical care and sleep medicine. There are 3 pulmonologists based in the practice, located in St. Charles, MO. We have conducted clinical research since 1990.

Our facility specializes in pulmonary and sleep medicine related clinical research activities. We have worked with numerous major pharmaceutical companies and several CRO's performing phase II, III and IV studies. Trials have been conducted in COPD, asthma, AECB, atrial fibrillation, DVT/PE, pneumonia, obesity, and nocturnal hypoxemia. We have also performed phase IIIb studies.

Our office conducts inpatient and outpatient based clinical trials. Full pulmonary medicine facilities are available in our office including complete PFT's, exercise testing, ECG, Holter monitoring, serial spirometry, serial PK's, oxygen saturation measurements, six-minute walk testing, and phlebotomy. We are also capable of outpatient infusion trials. The adjacent hospital has full radiology facilities (including high-resolution CT scanning), exercise physiology lab and 6-bed AASM accredited sleep lab with paper recording capability on two of six beds.

>Thomas M. Siler, MD is board certified in Internal Medicine, Pulmonary Diseases, Critical Care Medicine and Sleep Medicine. He has conducted clinical research in his practice since 1990 in both inpatient and outpatient studies. He has been principal investigator in over 70 trials. He has attended IRB sponsored GCP training. Subinvestigators include Frank Calandrino, MD, Sergio G. Garcia, M.D., Stacey Brown APRN, V. Christine Champagne APRN, CCRC, and Jill Aufmuth, APRN.

Mitchell Champagne, RPh, CCRC is director of research. He has conducted numerous clinical research trials since 1997.

Marcia Gaddy, RN, CCRC is a study coordinator. She has conducted clinical research since 1999.

Billie Greenwell, RN, CCRC is a study coordinator. She has conducted clinical research since 2002.

Krista Haggard, RMA CCRC has been involved in healthcare in our office since 1993 and has recently joined our research team as our newest Certified Coordinator.

Adult subjects with lung and sleep disorders are available through our private practice. We have more than 6,000 active patients in our practice. We also have access to subjects throughout the St. Louis metropolitan area with a population of over 2 million. We have arrangements for local lodging nearby for accommodating patients requiring long study visits who live outside our immediate area.

We can use central IRB's for outpatient studies. For inpatient studies, our adjacent hospital has a very proactive IRB that meets on a regular basis with decisions concerning approval of protocols made in a reasonable period of time.

CenterWatch is listing the following trials that are actively recruiting patients at this center.

• Can't Breathe?
• COPD Volunteers Needed
• Has your doctor told you that you have Atrial Fibrillation (AF)?
• Short of Breath? Check to see if you qualify for participation in a COPD Research Study

For more information, please contact:

Mitchell Champagne RPh, CCRC
Research Director
Midwest Chest Consultants, PC
330 First Capitol Drive, Suite 470
St. Charles, MO 63301-2847 USA
Phone: 636-946-1650
Fax: 636-757-1900
E-mail:

If you are interested in contacting this center to discuss placing a clinical trial there, please complete and send the E-mail form below. A representative from the research center will then follow up with you.

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Last updated on August 21, 2008