University of Louisville Department of Cardiovascular Medicine Research Division

Center Information

Rachel Sheppard
Clinical Regulatory Director
University of Louisville Department of Cardiovascular Medicine Research Division
Department of Cardiovascular Medicine 550 South Jackson St, Suite ACB A3L42
Louisville, KY 40202
USA
502-852-1006
(502) 852-6474 (fax)
CTU@louisville.edu
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Currently Enrolling Trials

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Therapeutic Areas

Cardiology/Vascular Diseases

Center Overview

The Department of Cardiovascular Medicine at the University of Louisville School Of Medicine is a vibrant and dedicated clinical department devoted to providing comprehensive and innovative cardiovascular care to the community of Kentucky and Southern Indiana.

The division of cardiology serves three local hospitals (Kentucky One - University of Louisville Hospital, Kentucky One – Jewish Hospital, and Robley Rex VA Medical Center) and provides outpatient cardiology services at several clinical facilities across the Northern Kentucky and Southern Indiana. The University of Louisville Hospital, James Graham Brown Cancer Center and Kentucky One Healthy joined in a partnership in 2014 with a joint operating agreement fortifying the academic and medical services with a statewide medical network to allow for the expansion of innovate care throughout the state of Kentucky.

Performance Metrics

ACRP Certifications

Clinical Research Experience

Our clinical research in advanced heart failure, regenerative medicine, structural heart disease and cardiovascular critical care are among the fastest growing research programs in the state, enrolling patients in important clinical trials with potentially life saving and innovative treatments. Our cardiac stem cell research is nationally recognized and focused on addressing the growing epidemic of heart failure. University of Louisville Department of Cardiology is an esteemed member of the Cardiovascular Cell Therapy Research Network (CCTRN). The National Heart, Lung and Blood Institute (NHLBI) funds the CCTRN. The CCTRN includes seven main stem cell centers in the United States with experience and expertise in clinical trials studying treatments for heart and vascular disease.

Therapeutic Areas:

  • Advanced Heart Failure / Cardiac Transplant / Ventricular Assist Devices
  • Cardiovascular Imaging
  • Cardio-Oncology
  • Critical Care Cardiology
  • Electrophysiology
  • Environmental Cardiology
  • General Cardiology
  • Interventional Cardiology
  • Preventative Cardiology
  • Regenerative Medicine / Cardiac Stem Cells
  • Structural Heart Disease
  • Vascular Disease

Affiliations:

Facility Description

1.) Kentucky One - University Of Louisville Hospital
The center offers both inpatient and outpatient facilities University of Louisville Hospital has 329 beds. The hospital has an average of 17,000 admissions per year with approximately 5,000 annual inpatient and 8,000 outpatient surgeries. Its emergency room department delivers over 65,000 visits annually. University of Louisville Hospital is the academic level one trauma hospital at the heart of the Louisville Metro area. The doctors, nurses and staff at University of Louisville Hospital are pioneering the treatments that will shape the future of health care. The University of Louisville Hospital is a state of the art facility with all of the necessary equipment essential to providing the highest quality inpatient and outpatient cardiovascular care. Our division has full complement of cardiac imaging including Cardiac MRI, SPECT, CT, echocardiography (with 3-D imaging available). The hospital has two full time cardiac catheterization and EP laboratories with experienced staff. The hospital also has CLIA certified, laboratory, pharmacy, and a cardio-pulmonary diagnostic lab available for research use.

Our Cardiology Clinical Research Division is completely outfitted with the equipment and resources to accomplish research objectives in line with ICH/GCP guidelines through the use of University of Louisville’s Clinical Trials Unit (CTU). The CTU facility can accommodate all types of research requirements from Phase-I through Phase-IV studies. The following equipment is available at our site for research purposes:

  • Research Laboratory Equipment
    • -70°C and -20°C specimen freezers
    • -2°C to 8°C specimen refrigerator
    • -2°C to 8°C drug storage refrigerator
    • -9°C to 40°C centrifuges
    • Ambient centrifuge
    • 24/7 networked, temperature monitoring
  • Clinical Equipment
    • Electrocardiography (ECG)
    • Sphygmomanometers
    • Dynamap
    • Infusion pumps
    • Compounding Aseptic Isolator
    • Phlebotomy laboratory (complete with CLIA waiver)
  • Office Equipment & Facilities
    • Electronic scanner/fax/copier
    • High speed T1 ethernet access
    • TV/DVD/Cable for all day subject visits
    • 5 Dedicated exam rooms and 4 infusion bays
    • Monitor work area
    • Double lock drug cabinets
    • Phase-I, overnight room within the facility

2.) Kentucky One – Jewish Hospital
Jewish Hospital opened in 1905 with a mission to provide all patients with the highest quality care and a strong emphasis on research and education. Today, Jewish Hospital is a 462-bed, internationally renowned, high-tech tertiary referral center located in downtown Louisville, developing leading-edge advancements in cardiovascular services with a strong focus on management of advanced heart failure and cardiovascular critical care.

Ninety-five percent of the patients seen at Jewish Hospital come from within a 50-mile radius of the facility. In 2009, Jewish Hospital had 19,744 patient discharges, 9,092 emergency room visits, and 67,061 outpatient procedures performed. Many of the hospital’s clinical programs have achieved national rankings for excellence. The hospital is federally designated to perform all five solid organ transplants - heart, lung, liver, kidney, and pancreas. A full array of outpatient care services, including surgery and diagnostics, is available. Among these is a full array of imaging services, which includes but is not limited to PET, CT, MRI, and 3-D echocardiography.

Jewish Hospital has 7 cardiac catheterization laboratories and 8 cardiac operating rooms. Approximately 8,000 procedures are performed in catheterization labs and 1,300 cardiac surgical operations are performed per year at Jewish Hospital.

The Center for Advanced Heart Failure and Cardiothoracic Transplantation at Jewish Hospital ranks among the best in the nation, not only in terms of volume (in 2010, our volume of LVADs was in the top five nationwide) but also in terms of personnel and facilities. The LVAD program at Jewish Hospital is one of the premiere programs in the country. The program has successful bridge-to-transplant, destination therapy, and a bridge-to-recovery program. The Center for Advanced Heart Failure and Cardiothoracic Transplantation has a solid foundation in clinical trials with a stellar track record for participating in innovative clinical studies.

3.) Robley Rex VA Medical Center
Robley Rex Veterans Affairs Medical Center is a general medical and surgical hospital in Louisville with a 116 beds. The clinical cardiology faculty at Robley Rex VA have joint faculty appointments with the University of Louisville. The VA facility offers full complement of both inpatient and outpatient cardiovascular services. On average there more than 5,000 outpatient general cardiology office visits per year. The Robley Rex VA has two cardiac catheterization and EP laboratories with a volume of 1,000 diagnostic catheterizations, percutaneous interventions, EP ablations, and device implants per year. The VA has full array of cardiac diagnostic procedures: ECG, echocardiography (with 3-D available), SPECT, cardiac MRI, and cardiac CT available on site. The cardiology faculty at the Robley Rex VA participates in numerous industry and investigator initiated clinical trials.

Contact Center

If you are interested in contacting this center to discuss placing a clinical trial there, please complete and send the email form below. A representative from the research center will then follow up with you.