Trial Information

Summary: High Carbohydrate Versus High Fat Diets in the Treatment of Obesity (JBR 0512)

The purpose of this study is to compare the ability of low calorie high carbohydrate and low calorie high fat/protein diets to decrease abdominal fat in overweight and obese subjects. The investigators will also test the effects of these diets on secondary outcomes including body composition, fluid and electrolyte balance, lipids and lipoproteins, blood pressure, arterial compliance, glucose and insulin metabolism, bone turnover, and measures of satiety. This is a 10 week inpatient study.

Patient Inclusion Criteria:

• Man or a woman with a body mass index (BMI) of 30 to 34.9
• Man with a BMI of 25 to 29.9 with a waist circumference > 102cm (40in)
• Woman with a BMI of 25 to 29.9 with a waist circumference > 88cm (35in)

Patient Exclusion Criteria:

• High Blood Pressure
• High Cholesterol
• Diabetes
• HIV positive
• Syphilis
• Hepatitis B/C positive

If you would like to learn more about participating in this study, please send an e-mail message using the form below.