Trial Information

Summary: Transcranial Magnetic Stimulation (TMS) in the Treatment of Major Depression

This study is a trial of an outpatient, non-medication, non-invasive investigational treatment called Transcranial Magnetic Stimulation (TMS). TMS applies a magnetic field to the brain for a brief period of time. We are testing whether TMS can treat major depression.

Participants will be randomly assigned to either active rTMS or sham (placebo) rTMS. If patients receive sham and do not improve, they have the option of receiving real TMS.

Study Criteria:

• Patients must be ages 21-70, with current Major Depression.
• The study is for patients for whom medications have not worked or have not been tolerated.

Some exclusion criteria are:

• Prior treatment with Transcranial Magnetic Stimulation (TMS) or Vagal Nerve Stimulation (VNS)
• Metal objects in head
• Pregnancy/Breastfeeding
• Neurological Disorder
• History of Seizure or Stroke

For more information,

If you would like to learn more about participating in this study, please send an e-mail message using the form below.