Trial Information

Summary: Genetic Determinants of Peripheral Arterial Disease

The role of genetics in determining whether patients with coronary artery disease also have circulation problems in the legs needs to be evaluated. The purpose of this research study is to identify genetic factors in peripheral arterial disease, study the interaction between environmental and genetic factors in the incidence and progression of the disease, and identify factors that cause differences in the severity of the vascular disease in different parts of the body. This study will involve evaluating 2,000 patients, 1,000 at Mount Sinai Medical Center and 1,000 at Stanford University over the course of five years. This study involves three questionnaires, measuring blood pressures in the arms and legs and the collection of blood samples for coagulation factors, plasma, and DNA analysis. It takes approximately 2 hours to complete this study.
No Compensation Provided

Patient Inclusion/Exclusion Criteria:

1. Patients who are scheduled for a non-emergent cardiac catheterization
2. Patients who have angiographically confirmed coronary artery disease.
3. Patients who can understand and sign the informed consent form.
4. Patients over age 40.

1. Pregnant women
2. Minors.
3. Mentally handicapped patients who cannot understand and sign the informed consent.

If you would like to learn more about participating in this study, please send an e-mail message using the form below.