Trial Information

Summary: Pre-diabetes: Are you at risk?

At least 16 million people in the United States (15.6% of the population), ages 40 to 74, have pre-diabetes. Washington University School of Medicine is conducting a research study that can give you vital information regarding your personal health. You will be compensated for time and travel. Trial lasts up to 12 weeks, or six visits. Participants will need to have transportation to Barnes-Jewish.

The overall purpose of this study is to determine the impact of depression on insulin resistance (IR) in diabetes. Insulin resistance characterizes type-2 diabetes (T2DM) and is a predictor of diabetes complications, particularly coronary heart disease (CHD). CHD, in turn, accounts for more than 50% of deaths and 75% of hospitalizations among diabetic patients. The findings from this study could identify a potentially modifiable factor for improving the course and outcome of those living with T2DM.

If depressed, the participant will be treated with cognitive behavioral therapy ("a form of counseling or talk therapy") or usual depression care. If not, participants will not have counseling, but will be asked to complete several questionnaires and undergo testing for risk factors.

Inclusion Criteria: Ages 18-80, first generation family history of diabetes, obesity, uni-polar depression, gestational, birth to baby weighing at least nine pounds, high blood pressure, anxiety, heart disease. Also, you are at higher risk if you fall into one of these categories; African American, Asian American, Native American, Pacific Islander, Alaskan Native, Hispanic.

Exclusion Criteria: Bi-polar depression, schizophrenia, diagnosed Type 2, advanced kidney or heart disease.

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Trial listings updated: June 1, 2008 at 5:43:45 AM