Trial Information

Summary: Hyperpolarized Helium-3 MR Lung Imaging Findings in Asthmatics. HIC #: 8559

This research study evaluates how air moves through the lungs of people with asthma. To do so, we will use magnetic resonance imaging (MRI) to look at an Investigational New Drug which is a special helium gas (called hyperpolarized helium-3) as it goes through the lungs during breathing. We hope to learn more about asthma by watching air moving through the lungs. In the future this may help us tell whether someone has asthma, decide whether medications are working, or determine when someone is likely to have an attack of asthma.

You will complete a questionnaire about your medical history and any lung problems. You will also have a chest x-ray, a physical exam, spirometry, an electrocardiogram (ECG), a urine test and a blood test before the MRI. These tests, except for the chest x-ray, will be repeated immediately after the MR scan. The MR imaging session can be expected to be between 1 and 2 hours.

You may be eligible if you have asthma and you are between 12 and 35 years old. You should not participate in this study if you are pregnant, or if you have any metal splinters or shards in your body or any other reasons that could interfere with the MRI scanning.

If you would like to learn more about participating in this study, please send an e-mail message using the form below.