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Therapeutic Areas: Psychiatry/Psychology | Pediatrics/Neonatology
Disease Category: Obsessive-Compulsive Disorders

Trial Information

Maximizing Treatment Outcome in OCD
New York State Psychiatric Institute, New York City

This study compares the effectiveness of two proven treatment strategies for OCD patients who are currently on a serotonin reuptake inhibitor (SRI, i.e., clomipramine, fluoxetine, fluvoxamine, paroxetine, sertraline, citalopram, or escitalopram) but still have residual symptoms. Participants remain on their current medication and receive either cognitive-behavioral therapy (CBT) consisting of exposure and ritual prevention or an additional medication (risperidone). The goal is to compare these two augmentation strategies, each of which has been found effective in prior studies. All treatment is at no charge. Note: Patients who do not improve after 8.5 weeks of treatment will be offered at no-cost the treatment they did not initially receive (either the CBT or the add-on medication).

PatientInclusionCriteria

  • 18-70 years
  • Genders: both

Key Inclusion Criteria:

  • Primary diagnosis of OCD
  • Currently on a stable and adequate dose of an SRI

Patient Exclusion Criteria:

  • Medical or psychiatric conditions that would make participation in the study unsafe
  • Patients who have already had an adequate trial of these augmentation strategies while on a serotonin reuptake inhibitor

New York State Psychiatric Institute
New York State Psychiatric Institute
1051 Riverside Drive #69
New York NY 10032
Phone: 212-543-5367

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Research Center Information: New York State Psychiatric Institute

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