Trial Information

Summary: Want to Quit Smoking?

The purpose of this study is to assess the value of nicotine patch therapy in combination with nicotine-free cigarettes as a step toward quitting smoking successfully. Conventional FDA approved nicotine patches will be used.

This study consists of 1 physical screen and 7 visits over a 12 week period. The physical will take approximately 2-2½ hours and includes a drug screen. If you test positive for illegal drugs you will not be eligible to participate. The 7 visits will each last approximately 45 minutes and will take place between 9AM and 5PM Monday through Friday. If you complete all laboratory visits you will be compensated up to $140.

If you pass the physical screen, we will ask you to come in for your 1st visit about 5-7 days later. At this visit you will receive a supply of nicotine patches and cigarettes without nicotine. You will be asked to only use our supplies for the next two weeks. You will also be asked to set your quit smoking date 2 weeks from the date of your 1st visit.

After your quit date, you will continue to wear the study nicotine patches but not smoke any type of cigarette. After 6 weeks we will gradually lower your nicotine patch dosage.

All seven study visits will have the same format. We will measure the carbon monoxide in your breath, collect a saliva sample and take your heart rate and blood pressure.

Patient Inclusion Criteria:

• Adult males and non-pregnant adult females between the ages of 18 - 65.

Patient Exclusion Criteria:

• Drug free

If you would like to learn more about participating in this study, please send an e-mail message using the form below.