Trial Information

Summary: Refractory Epilepsy and acute repetitive seizures (ARS)

We are conducting a clinical research study for volunteers diagnosed with Refractory Epilepsy with acute repetitive seizures (ARS) that require intermittent medical intervention. This study tests the effectiveness and safety of an investigational drug for the management of selected refractory patients with episodes of ARS.

Study Criteria:

• Age = 2
• Diagnosis of Epilepsy
• Stable dose of AED for at least 2 weeks
• Patients receiving vagus nerve stimulation (VNS) are eligible if they have been on VNS for at least six months and the settings have been stable for 2 weeks
• Experienced at least 2 episodes of ARS in the last yea=r, one of which must have occurred in the previous six months
• Sufficient muscle mass for an injection into the thigh muscle
• has a responsive caregiver, 18 years of age and older that can administer study drug and monitor patient seizures and respiratory rate
• No pregnant or lactating women
• No history of consistent progression from episodes of ARS to status epilepticus
• No history of failure to respond to benzodiazepine treatment
• No hypersensitivity to diasepam
• No acute narrow angle glacoma
• No alcohol or substance abuse
• No investigational drug within 30 days
• No acute or progressive neurological disease, severe psychiatric disease, or severe mental abnormality
• no significant cardio-respiratory, renal or hepatic condition

If eligible, you will receive investigational drug and study-related medical tests at no cost. Compensation for time and travel may also be available.

For additional information about this study or to enroll, visit our website: www.clinicaltrialsinc.com

If you would like to learn more about participating in this study, please send an e-mail message using the form below.