Trial Information

Summary: Primary Immune Deficiency Disorder (PIDD) - Adults and minors

People with primary immune deficiency disorder (PIDD) are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

• Are between the ages of 6 and 75
• Have been diagnosed with chronic primary immune deficiency disorder (PIDD)
• Are currently on IGIV replacement therapy at a fixed interval and dosage with a total monthly infusion of IgG between 300 and 800 mg/kg that has been unchanged for at least 3 months

You may not participate in this study if you:

• Have a known history of significant adverse reactions to other IgG or blood products
• Have a history of allergic reaction to products containing IgA or have a history of antibodies to IgA
• Have a history of kidney failure
• Have a known history or current diagnosis of deep venous thrombosis (blood clots)
• Have chronic lymphocytic leukemia, lymphoma, multiple myeloma, HIV infection, AIDS or chronic or recurrent neutropenia
• Current use of daily corticosteroids, such as prednisone
• Have known non-controllable arterial hypertension
• Have anemia
• Have an active viral or bacterial infection or symptoms consistent with such an infection within the two weeks prior to study start
• Have a history of illegal drug use within 3 months prior to study start
• Are pregnant, breastfeeding, or intend to become pregnant during the study
• Have participated in another research study within the last 30 days

If you would like to learn more about participating in this study, please send an e-mail message using the form below.