Trial Information

Summary: Systemic Lupus Erythematosus (SLE) - Adults

People with systemic lupus erythematosus are asked to participate in a research study being conducted by The Feinstein Institute for Medical Research.

You may be eligible to participate in this study if you:

• Are at least 18 years of age
• Have been diagnosed with SLE

You may not participate in this study if you:

• Have any serious disorder (including psychiatric) other than a diagnosis of SLE (ex. Congestive heart failure, angina, chronic obstructive pulmonary disease, asthma, and malignancies)
• Have uncontrolled hypertension or diabetes
• Have signs or symptoms of a viral infection or bacterial infection within 30 days of study start, or a recent history of repeated infections
• Have a presence or history of vasculitis (comprising internal organs or extremities, or leading to peripheral neuropathy) within the last 3 years, presence or history of active CNS lupus (defined as seizure disorder, cerebral vascular accident, psychosis due to SLE, encephalitis, meningitis, or myelitis) requiring therapy within the last 3 years.
• Have evidence of liver disease, moderate to severe anemia, neutropenia, or thrombocytopenia
• Take oral or IV cyclophosphamide (or any other alkylating agent), cyclosporine (Neoral), tacrolimus (Prograf), sirolimus (Rapamune), IV immunoglobin, and/or plasmapherisis within 3 months
• Are currently receiving mycophenolate mofetil (CellCept) or azathioprine (Imuran)
• Have a positive protein purified derivative (PPD) test
• Are HIV, hepatitis B, or hepatitis C positive
• Have received a live vaccine within 3 months
• Have had prior administration of another biologic that primary targets the immune system (eg. Rituxmab, Lymphostst-B, TACI-IG and CTLA4-Ig) within 1 year
• Have donated blood or experience a loss of blood (more than 500mL) within 4 weeks of study start
• Have a history of drug or alcohol abuse within the last one year
• Are pregnant, breastfeeding, or intend to become pregnant during the study
• Have participated in another research study within the last 30 days

For More Information,

If you would like to learn more about participating in this study, please send an e-mail message using the form below.