Trial Information
Summary: A Study of NT-Pro Brain Natriuretic Peptide (NT-proBNP) in Patients With Acute Heart Failure.
Status: Recruiting
Protocol Number: BOT_1
Sponsor:
Company Division: Diagnostic
Official Scientific Title: NT-proBNP in the optimization of treatment after recent acute heart failure (BOT-Acute HF) trial.
Brief Summary: This study will assess whether measurement of NT-proBNP levels before discharge from hospital after acute heart failure improves the prognosis of patients, with respect to major cardiovascular events (cardiovascular hospitalizations and cardiac deaths).
Study Phase: N/A
Study Design / Study Details:
- Purpose:
- Allocation: Randomized
- Masking: Open Label
- Control:
- Assignment: Parallel
- Endpoints:
Study Type:
Interventional
Condition: Heart Failure
Intervention Type: Diagnostic Test
Intervention Name: ELECSYS®proBNP
Primary Outcome:
Key Secondary Outcomes:
Inclusion Criteria:
- adult patients, >=18 years of age;
- hospital admission for acute heart failure, class III or IV;
- requirement for intravenous therapy.
Exclusion Criteria:
- clinical or laboratory evidence of an acute coronary syndrome;
- major arrhythmias as the main cause of symptoms;
- PTCA or CABG planned in next 3 months;
- non-cardiac concomitant diseases which may have an important influence on outcome as primary factor.
Gender: Males or Females
Age Limits: Min: 18 Years
Accepts Healthy Volunteers: No
Anticipated Start Date: July, 2006
Trial Registration Date: 08/22/2007
Date Last Updated: 08/28/2007
Link To Trial Results
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Contact:
Research Site:
Located In:
Brescia, Italy, 25123
Telephone: 973-235-5000 or 800-526-6367
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Trial listings updated: October 6, 2008 at 2:44:39 PM