Trial Information

Summary: Bothered by Arthritis? Concerned About Heart Disease?

The PRECISION Trial is a research study that will compare 3 approved medicines commonly used to treat pain in people who have osteoarthritis (OA) or rheumatoid arthritis (RA) and have or are at risk for heart disease.

The 3 approved medicines included in the trial are celecoxib (brand name Celebrex), ibuprofen (brand names include Advil, Medipren, Motrin, and Nuprin), and naproxen (Aleve, Anaprox, Naprelan, and Naprosyn).

The PRECISION Trial will help doctors learn more about the long-term heart safety of these medicines. The trial will help provide the information doctors need to choose the most appropriate pain reliever for their patients who have OA or RA and have or are at risk for heart disease.

Benefits of Participating. By participating in PRECISION, you will

• Receive study-related check-ups and study medication at no charge
• Obtain study-related medical care during the trial
• Help others by contributing to medical research

About 20,000 people will be participating in the PRECISION from countries around the world. See if you qualify.

To participate in PRECISION, you must meet the basic requirements below:

• Be 18 years of age or older
• Have had OA or RA for at least 6 months
• Have been prescribed regular medication for your OA or RA pain for at least 6 months
• Have or be at high risk for heart disease (for example, if you've had a heart attack or stroke, or have diabetes)

The study doctor can tell you if you meet all of the requirements.

Patient Exclusion Criteria - Please see the inclusion criteria.

If you would like to learn more about participating in this study, please send an e-mail message using the form below.