Trial Information

Summary: The effect of estrogen and DHEa supplementation on serum lipids, muscle mass, strength and endurance.

The overall goal of this study is to examine the effect of replacement with a combination of conjugated estrogen and DHEA to menopausal women on serum endocrine levels, serum lipid parameters as well as muscle mass, strength and endurance. It is thought that the combination of estrogen and androgen replacment therapy will provide physiologic replacement of sex steroids, increase muscle mass, strength and endurance with no dramatic impact on serum lipid levels comparted to supplementation with estrogen alone and compared to placebo.

The study will last for three months, during which patients will take medication, undergo muscle strength testing and some may have an MRI.

Participants will be compensated for time and effort and will recieve free health exam at beginning and end of the study.

Study Criteria:
To qualify for this study, you must be between 45-70 years of age; have no menstrual cycle for at least one year, or min of 6 months with and FSH level above 40miU/ml; if you are currently taking estrogen replacement therapy or DHEA supplementation you will be required to stop taking this medication for 60 days prior to the study; have a normal pap smear and have had a mammogram in the last year.

If you would like to learn more about participating in this study, please send an e-mail message using the form below.