NIH Studies: Hematology

Below is a listing of government-funded clinical trials in Hematology, being conducted by the various National Institutes of Health at the Warren Grant Magnuson Clinical Center in Bethesda, MD.

Click on a study summary to view the study description and contact information directly from the NIH's web site.

Molecular and Clinical Studies of Primary Immunodeficiency Diseases

Therapeutic Application of Intravascular Nitrite for Sickle Cell Disease

Studies of Phlebotomy Therapy in Hereditary Hemochromatosis

An Evaluation of the Safety and Efficacy of Escalating Doses of AMD3100 to Mobilize CD34+ Cells in Healthy Volunteers

A Randomized Trial of Rabbit ATG/CsA vs Campath-1H in Aplastic Anemia Patients with Refractory Pancytopenia or Suboptimal Hematologic Response After h-ATG/CsA Treatment

Evaluation of Hematologic Patients - Training Protocol

Collection of Blood and Bone Marrow from Normal Volunteers and Patients for Research Purposes

Evaluation and Treatment of Fasting Hypoglycemia

Are Left Ventricular Abnormalities Associated with Pulmonary Hypertension in Sickle Cell Anemia?

Apheresis Procedures to Obtain Plasma or Leukocytes for In Vitro Studies

Apheresis of Family Members of Patients Undergoing Allogeneic Bone Marrow Transplantation. A Pre-Clinical Study of Selective Depletion of Donor Lymphocytes to Prevent Acute Graft-Versus-Host Disease

Exploratory Study of Non-Myeloablative Allogeneic Peripheral Blood Stem Cell Transplantation and Donor Lymphocyte Infusions for Metastatic Neoplasms Refractory to Standard Therapy

Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection (Job) Syndrome

Non-myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematologic Malignancies in High Risk Patients and in Patients with Debilitating Hematologic Diseases

Filgrastim-Mobilized Peripheral Blood Stem Cells for Primary Allogeneic Transplantation Using Unrelated Donors Participating in the National Marrow Donor Program (NMDP)

Studies of the Natural History of Sickle Cell Disease and Other Hemolytic Disorders

Peripheral Blood Granulocyte Mobilization and Gene Expression Profiling in Adult Individuals of African Descent, with and without Benign Ethnic Neutropenia

Genetics and Pathophysiology of Familial Mediterranean Fever and Related Disorders

Collection and Distribution of Blood Components from Healthy Donors for In Vitro Research Use

A Pilot Study of Recombinant Humanized Anti-IL-2 Receptor Antibody (Daclizumab) in Patients with Moderate Aplastic Anemia, Pure Red Cell Aplasia, Amegakaryocytic Thrombocytopenic Purpura, or Relapsed Severe Aplastic Anemia

High-Dose Cyclophosphamide with CD34+ Selected Autologous Hematopoietic Cell Support for Treatment of Refractory Chronic Autoimmune Thrombocytopenia

Cytokine Gene Polymorphisms in Bone Marrow Failure

Investigations of Megakaryocytes from Patients with Abnormal Platelet Vesicles

Disease Pathogenesis and Natural History of Lipid Disorders

Cytokine Gene Polymorphisms in Allotransplant Donors

The Role of Nitrite in Preconditioning Mediated Tolerance to Ischemic Stress

A Pilot Trial of an Accelerated Immunization Schedule with ALVAC-pp65 (vCP260) for Inducing CMV-Specific Immunity in Stem Cell Allotransplant Donors and Healthy Volunteers

A Phase I, Open-Label, Multiple-Center, Single-Dose, Dose-Escalating, Safety, Tolerability, Immunogenicity, Pharmacokinetic and Pharmacodynamic Study of GMA161 in Patients with Idiopathic Thrombocytopenic Purpura (ITP)

A Pilot Study of Alemtuzumab (Campath) in Patients with Relapsed or Refractory Severe Aplastic Anemia

A Pilot Study of Recombinant Humanized Anti-CD20 Antibody (Rituximab) in Patients with Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan Anemia

Identification of Genes Expressed in Atherosclerotic Plaques

Screening Protocol for Patients with Bone Marrow Failure States, Isolated or Multilineage Cytopenias, or Hematologic Malignancies

Ex Vivo Selective Depletion of Alloreactive Donor T-Lymphocytes Utilizing RFT5-SMPT-dgA, a Specific Anti-Interleukin-2 Receptor Immunotoxin

Use of Granulocyte Colony Stimulating Factor Mobilized Leukapheresis Collections from Normal Volunteers to Develop Improved Methods of Stem Cell and Lymphocyte Selection for Allogeneic Transplantation

Evaluation of Healthy Volunteer Marrow Donors Participating in the National Marrow Donor Program (NMDP)

Atorvastain Therapy To Improve Endothelial Function in Sickle Cell Disease

A Phase III, Open-label, Extension Study of Eculizumab in Patients with Transfusion Dependent, Hemolytic Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Participated in the TRIUMPH (C04-001), SHEPHERD (E05-001) or X03-001 Studies

Citrate Effects and Bone Density Studies in Long-Term Apheresis

SHEPHERD: Safety in Hemolytic PNH Patients Treated with Eculizumab: A Multi-center Open-Label Research Design Study

Recruitment of Peripheral Blood Hematopoietic Progenitors by Granulocyte Colony Stimulating Factor

Evaluation of Endothelial and Hemodynamic Function in HIV Associated Pulmonary Hypertension and a Phase I/II Safety and Efficacy Trial of Sildenafil in HIV Associated Pulmonary Hypertension

An Open-Label, Baseline-Controlled Study of the Safety and Efficacy of SeeMore (EVP 1001-1 Injection) in Heart Patients

A Prospective, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study of Nitric Oxide for Inhalation in the Acute Treatment of Sickle Cell Pain Crisis

Lymphapheresis of Patients with Pancytopenia

Last updated: September 15, 2006 at 4:30:37 PM