NIH Studies: Endocrinology

Below is a listing of government-funded clinical trials in Endocrinology, being conducted by the various National Institutes of Health at the Warren Grant Magnuson Clinical Center in Bethesda, MD.

Click on a study summary to view the study description and contact information directly from the NIH's web site.

Treatment of Nonalcoholic Steatohepatitis with Metformin

Inhibition of Intestinal Glucose Absorption by the Bioflavonoid Quercetin in the Obese and in Obese Type 2 Diabetes

FSH-Stimulated Inhibin B as a Marker for Early Ovarian Insufficiency

Evaluation of the Immune Response in Humans After Exposure to Hepatitis C Virus

Pilot Program for Targeted Prevention of Adolescent Weight Gain

Effect of AC2993 (Synthetic Exendin-4) - Administered Alone or in Combination with Rapamycin and FK506 - On Islet Function in Patients with Type I Diabetes

Pulse Dexamethasone Over 48 Weeks for Podocyte Disease

Effect of Leptin Therapy in the Treatment of Severe Insulin Resistance

Chronic Sleep Deprivation as a Risk Factor for Metabolic Syndrome and Obesity

Ingested Interferon Alpha: Prolongation or Permanence of the "Honeymoon" Phase in Newly Diagnosed Diabetes Mellitus

Sirolimus Monotherapy to Optimize Activation Induced Cell Death (AICD) in Renal Transplants Following Lymphocyte Depletion Induction with Thymoglobulin

Clinical and Molecular Analysis of ACTH-Independent Steroid Hormone Production in Adrenocortical Tissue

Methods for Assessing Insulin Sensitivity In Vivo

Study of Association of Serum Factors with Diabetic Retinopathy

Effect of Metformin on Energy Intake, Energy Expenditure, and Bodyweight in Overweight Children with Insulin Resistance

Urinary Vitamin C Loss in Diabetics

Evaluation of Endocrine-Related Conditions

Endocrine Studies in Health and Disease

Evaluation of the Gastrinoma in Patients with Zollinger-Ellison Syndrome

Supplemental Calcium in Overweight Out-Patients

Molecular Genetics of Retinal Degenerations

Lutein/Zeaxanthin and Omega-3 Supplementation in Persons Over Age 60

Evaluation of Rosiglitazone in Reversing Metabolic Defects of Pre-Diabetes and Type 2 Diabetes Mellitus

Effect of Regular Exercise on Vascular Function and Cardiovascular Risk in a Sedentary Work Force: The NHLBI "Keep the Beat" Program

Study of Thyrotropin Releasing Hormone in Normal Volunteers and in Patients with Thyroid or Pituitary Abnormalities

Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death

Depletional Induction with Rabbit Anti-Thymocyte Globulin, Followed by Two Approaches Toward Monotherapy Immunosuppression in Kidney Transplant Recipients

Free Fatty Acid Flux in African Americans

Decisions of Female Adolescents about Carrier Testing in Families with X-Linked Severe Combined Immunodeficiency (XSCID)

Remodeling of Chromatin-Based Epigenetic Structures in Development and Aging

Pharmacogenetics of Efavirenz Metabolism: Association of CYP2B6 Genotype and Prolonged Drug Exposure

Long-Term Treatment of Nonalcoholic Steatohepatitis With Pioglitazone

Collection and Storage of Umbilical Cord Hematopoietic Stem Cells for Sickle Cell Disease Therapy

Catecholamine Reserve and Exercise Tolerance in Subjects with Congenital Adrenal Hyperplasia and in Healthy Controls

Induction of Donor Specific Immunologic Hyporesponsiveness with Thymoglobulin, Sirolimus and Donor Bone Marrow Infusion

Determining the Prevalence and Prognosis of Secondary Pulmonary Hypertension in Adult Patients with Sickle Cell Anemia

Nonmyeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Tansplantation For Severe Congenital Anemias Including Sickle Cell Anemia, Thalassemia, and Diamond Blackfan Anemia

Genetic Analysis of Familial Keloids

Permeability Factor in Focal Segmental Glomerulosclerosis

Solitary Islet Transplantation for Type 1 Diabetes Mellitus Using Steroid Sparing Immunosuppression

Natural History Study of Patients with Excess Androgen

Studies of Genetic Heterogeneity in Patients with Lysosomal Storage Disorders

The Relative Effects of Androgen, Estrogen, and the Combination of Androgen and Estrogen on Growth Rate, GH Binding Protein, IGF-I, and Cognitive Function in Growth Hormone-Treated Girls with Turner Syndrome

An Open, Randomized, Long-Term Clinical Trial of Flutamide, Testolactone, and Reduced Hydrocortisone Dose vs. Conventional Treatment of Children with Congenital Adrenal Hyperplasia (CAH)

The Use of Omeprazole in Patients with Hypersecretion of Gastric Acid

Levels of Hormones in the Blood of Healthy Children

Family Studies in Metabolic Diseases and Mineral Metabolism

Studies with 1,25-Dihydroxycholecalciferol

Infrared Image Guided Minimally Invasive Live Donor Kidney Donation for Kidney Transplantation

Peripheral Thyroid Hormone Conversion and Glucose and Energy Metabolism

Adrenal Function in Critical Illness

Studies of Resistance to Vitamin D or Parathyroid Hormone

Body Heat Content and Dissipation in Obese and Normal Weight Adults

Long-Term Clinical Trial of Nitisinone in Alkaptonuria

Tolerance Induction Following Human Renal Transplantation Using Treatment with Humanized Monoclonal Antibody Against CD52 (Campath-1H)

Evaluation of Patients with Hyperthyroidism and Hypothyroidism

Studies of Hyperparathyroidism and Related Disorders

Live Donor Renal Donation for Allotransplantation

Acromegaly Treatment and Natural History

Studies of Molecular Genetics of Insulin Secretion, Insulin Action, and Diabetes Mellitus

Retinoids for Podocyte Disease

Medical Therapy of Zollinger-Ellison Syndrome

Internal Jugular Vein Sampling for ACTH Levels for the Differential Diagnosis of Cushing Syndrome

A Phase 1-2, Multicenter, Randomized, Double-Blind, Placebo Controlled, Prospective Study to Evaluate the Safety and Potential Efficacy of Single, Increasing Doses of TG100-115 in Subjects Undergoing PCI for Acute Ant ST Elev. MI

Screening Protocol for Patients Needing a Kidney, Kidney-Pancreas or Islet Cell Transplant

Safety and Efficacy of Orlistat (Xenical, Hoffmann LaRoche) in African American and Caucasian Children and Adolesents with Obesity-Related Comorbid Conditions

Evaluation of Women With Endocrine and Reproductive-Related Conditions

Population Differences in the Insulin Sensitivity, Resting Energy Expenditure, and Body Composition of Overweight Children and Children of Overweight Parents

Evaluation of Systemic Nitrite Infusion and Its Effect on Exercise Physiology and Metabolism

A Randomized Trial Comparing Intravitreal Triamcinolone Acetonide and Laser Photocoagulation for Diabetic Macular Edema

New Imaging Modalities in the Evaluation of Patients with Ectopic Cushing's Syndrome

Clinical and Laboratory Phenotyping in Humans with Informative Erythroid Phenotypes

Monitoring for Donor-Specific Hyporesponsiveness Following Renal and Pancreatic Allotransplantation

Last updated: September 15, 2006 at 4:30:37 PM