NIH Studies: Psychiatry/Psychology

Below is a listing of government-funded clinical trials in Psychiatry/Psychology, being conducted by the various National Institutes of Health at the Warren Grant Magnuson Clinical Center in Bethesda, MD.

Click on a study summary to view the study description and contact information directly from the NIH's web site.

The Antidepressant Efficacy of the Anticholinergic Scopolamine

The Evaluation of Patients with Mood and Anxiety Disorders and Healthy Volunteers

Double Blind Trial of DC Polarization in FTD

PET Imaging of Dopamine D2 Receptors and Extracellular Dopamine with (18F)Fallypride, D-amphetamine, and Alpha-Methyl-Para-Tyrosine in Healthy Subjects

Investigating the Role of Serotonin in Emotional Processing Through the Use of Tryptophan Depletion

Evaluation of SubstanceP Neurotransmission in Panic Disorder by PET Imaging of NK1 Receptors with [18F] SPA-RQ

Psychopharmacology Investigations of Fear Conditioning in Humans

Acamprosate for Central Nervous System Hyperexcitability and Neuroadaptation in Alcohol Withdrawal

Assessment and Treatment of People with Alcohol Drinking Problems

Adolescence, Puberty, and Emotion Regulation: An fMRI Study

The Evaluation of Patients with Autism Spectrum Disorders and Healthy Volunteers

Investigation of the Rapid (Next Day) Antidepressant Effects of an NMDA Antagonist

An Investigation of a Pharmacologic Strategy to Bring About Rapid (Next Day) Antidepressant Effects

Biochemical, Physiological, and Psychological Measures in Normal Controls and Relatives of Psychiatric Patients

The treatment of Menstrually-Related Mood Disorders with Extended Versus Interrupted Oral Contraceptives

Clinical Trial of the Cannabinoid CB1 Receptor Antagonist, SR141716 (Rimonabant), to Reduce Voluntary Ethanol Drinking in Healthy, Non-Treatment Seeking Individuals Who Consume Between 20 and 40 Drinks Per Week

Association Between Adenosine Receptor Gene Polymorphisms and Psychiological Responses to Caffeine in Subjects with Panic Disorder and Health Controls

Treatment of Winter Depression with Pharmacological Suppression of Melatonin Secretion

Fluoxetine's Effects on Attention and emotional memory in Anxious and Depressed Youth

Prospective Assessment of Functional Status, Psychosocial Adjustment, Health Related Quality of Life and the Symptom Experience in Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation

An Investigation of the Efficacy of Mercury Chelation as a Treatment for Autism Spectrum Disorder

An Investigation Examining the Evidence for Mitochondrial Dysfunction in the Pathophysiology and Treatment of BPD

An Endocrine Model For Postpartum Mood Disorders

The Phenomenology and Biophysiology of Climacteric and Menopause-Related Mood and Behavioral Disorders

Biological Markers in Childhood Psychiatric Disorders

A Longitudinal Investigation of Siblings of Schizophrenic and Manic-Depressive Patients

Candidate Genes in Obsessive-Compulsive Disorder

Biochemical Studies of Patients and Normal Volunteers

Non-Parametric and Parametric Linkage Studies of Stuttering

Dopamine Receptor Imaging in Mood Disorders

Effects of Arousal and Stress on Classical Conditioning

Serotonin 1A Receptor Imaging and Benzodiazepine Receptor Imaging in Panic Disorder and Posttraumatic Stress Disorder

Functional Neuroanatomy of Positive and Negative Affect in Alcoholics and Nonalcoholics

Adolescent Medial Temporal Lobe Function in Health and Illness

Reward-Related Processes and Brain Function

Severe Mood and Behavioral Dysregulation in Children: Pathophysiology and Treatment with Lithium

A Behavioral and Functional Neuroimaging Study of Inhibitory Motor Control

A Double-Blind Study Examining The Efficacy Of The Protein Kinase C Inhibitor Tamoxifen In The Treatment Of Acute Mania

Screening Evaluation for NIAAA Protocols

Serotonin1A Receptor Imaging In Mood Disorders

Investigating the Role of Norepinephrine in Emotional Processing through Alpha-2 Adrenergic Receptor Modulation

NK1 Receptor Antagonism for Treatment of Anxiety and Craving in Anxious Alcohol Dependent Subjects During Early Abstinence

A Clinical and Immunological Investigation of Regression in Autism

Timing of Voluntary Movement in Patients with Schizophrenia Using EEG and Surface EMG

The Efficacy of Phytoestrogens and Selective Estrogen Receptor Modulators in Perimenopause-Related Depression

Effect of Alprazolam on Fear-Potentiated Startle in Humans

Fear Conditioning Using Computer-Generated Virtual Reality

Changes in Activation Patterns in the Ventro-Medial Prefrontal Cortex of Healthy Adolescents During the Imagination and Observation of Aggressive Behavior

An Investigation of the Antidepressant Efficacy and Safety of an AMPAkine (Org 24448) in Major Depressive Disorder, A Double-Blind, Placebo-Controlled, Randomized Study

Effects of Hydrocortisone Infusion on Processing of Facially Expressed Emotion During Functional Magnetic Resonance Imaging

Brain Networks Responsible for Self-Agency: An fMRI study

Neuropsychiatric Correlates of Psychogenic Movement Disorder and Non-Epileptic Seizure

A Screening Protocol to Evaluate Women with Postpartum-Related Mood and Behavioral Disorders

Inpatient Evaluation of Neuropsychiatric Patients

Anatomic MRI Brain Imaging of White Matter in Children

The Effects of Fluoxetine on Measures of Domestic Violence

Muscarinic Cholinergic Receptor Imaging in Depression

The Effects of Mood and Tryptophan Depletion on the Neural Correlates of Affective Shifting in Mood Disorders

Cholinergic Modulation of Cognition and Emotion in Mood Disorders: Functional Neuroimaging Studies

Generalized Anxiety Disorder and Social Anxiety Disorder: Their Impact on the Processing of Social Emotional Information and Instrumental Learning

Bone Mineral Density in Patients with Major Depression with Melancholic and Atypical Features: Relation to Stress-System Neurohormonal Function

The Psychobiology of Temperament: An fMRI Study

An Investigation of the Efficacy in Childhood Obsessive-Compulsive Disorder of Riluzole: An Antiglutamatergic Agent

Clinical Molecular and Biochemical Characterization of Familial Presenile Dementia with Neuronal Inclusion Bodies

The Phenomenology and Neurophysiology of Affective Dysregulation in Children and Adolescents with Bipolar Disorder

PET Imaging of Brain 5-HT1A Receptors Using [11C](-)-RWAY

Randomized, Double-Blinded, Placebo Controlled Study of the Effects of Modafinil on Cognitive Function in Patients With Schizophrenia and Normal Controls Based on COMT Genotype

Functional MRI Study of Brain Mechanism Mediating Anhedonia in Major Depression

The Efficacy of 17Beta-Estradiol in Postpartum-Related Depressive Illness

Treatment of Patients with Alcoholism and Attention Deficit Disorder

5HT1A and SERT Imaging During Pharmacologically Induced Hypogonadotropic Hypogonadism With and Without Estrogen and Progesterone Replacement

The Effects of Acute Withdrawal of Estradiol on Mood Symptoms in Women with Perimenopausal Depression

Psychobiological Mechanisms of Resilience to Trauma

Randomized, Double-Blinded, Placebo Controlled Study Of The Effects Of Tolcapone On Cognitive Function In Patients With Schizophrenia And Normal Controls Based On COMT Genotype

Family Study of Affective and Anxiety Spectrum Disorders

Genetic Analysis of Attention Deficit Hyperactivity Disorder (ADHD)

Effect of D-Cycloserine on the Treatment in Social Phobia

Brain Activation in Response to Motivational and Affective Stimuli: Pharmacological Manipulations

Predictability and Aversive Expectancies in Anxiety Disorders

Combining a Dopamine Agonist and Selective Serotonin Reuptake Inhibitor for Treatment of Depression: A Double-Blind, Randomized Study

Neural Circuitry and Risk for Depression in Adolescents: A Study Using Functional Magnetic Resonance Imaging

Factors in Susceptibility to Ischemic Heart Disease in Major Depression: Documentation of Insulin Resistance in Patients with Major Depression Utilizing the Hyperinsulinemic Euglycemic Glucose Clamp

Neurobiological Mechanisms in Panic Disorder: Behavioral, Genetic, & Neural Correlates of Noradrenergic Function

PET Measurement of Regional Rates of Cerebral Protein Synthesis in Subjects with Fragile X Syndrome

The Development of Categorization

Antidepressant Effects on cAMP Specific Phosphodiesterase (PDE 4) in Depressed Patients

The Functional Neuroanatomy of Emotion Regulation in Major Depressive Disorder (MDD)

Influence of Age and Gender on Alcohol Metabolism and Acute Responses

Polyunsaturated Fatty Acids and the Neurochemistry of Cardiovascular and Motor Reactivity

Mechanisms of Individual Variation of Dextroamphetamine Effects in Normal Human Subjects

The Evaluation and Follow-up of Patients with Obsessive-Compulsive Disorder and OC Spectrum Disorders

The Treatment of Menstrually-Related Mood Disorders with Gonadal Steroid Replacement: An Endocrine Clamp Model

An Investigation of the Antidepressant Efficacy of an Antiglutamatergic Agent in Bipolar Depression

fMRI Investigation of Explicit Cure and Contexual Fear

Screening Protocol for Childhood Onset Psychotic Disorders

Intermediate Phenotype and Genetic Mechanisms for Psychosis and Cognitive Disturbance in 22q11.2-Hemideletion Syndrome

Neurocardiac Control in Major Depression

Last updated: September 15, 2006 at 4:30:37 PM