NIH Studies: Ophthalmology

Below is a listing of government-funded clinical trials in Ophthalmology, being conducted by the various National Institutes of Health at the Warren Grant Magnuson Clinical Center in Bethesda, MD.

Click on a study summary to view the study description and contact information directly from the NIH's web site.

Pilot Study of Intravitreal Injection of Ranibizumab (rhuFAB V2) for Advanced Ocular Disease of Von Hippel-Lindau Disease

Screening Study for the Evaluation and Diagnosis of Potential Research Subjects with Anterior Segment Disease

Clinical and Molecular Studies in Families with Myopia and Related Diseases

Phase II Study of Implants of Encapsulated Human NTC-201 Cells Releasing Ciliary Neurotrophic Factor (CNTF), in Participants with Visual Acuity Impairment Associated with Atrophic Macular Degeneration

National Ophthalmic Genotyping Network Stage 1 - Creation of DNA Repository for Inherited Ophthalmic Diseases

Clinical and Molecular Studies in Families with Glaucoma and Related Diseases

Evaluation and Treatment Protocol for Patients with Retinal Disease

Multicenter Uveitis Steroid Treatment (MUST) Trial Protocol

Use of Immune Cell Markers, Cytokines, and Transcription Factors as Markers of Intraocular Inflammatory Activity

Phenotype-Genotype Correlation in Aniridia

Screening Study for the Evaluation and Diagnosis of Potential Research Subjects with Ocular Inflammatory or Immunologic Diseases

Evaluation and Treatment Protocol of Patients with Corneal and External Diseases

Evaluation and Treatment Protocol for Potential Research Subjects with Inherited Ophthalmic Diseases

Screening Study for the Evaluation and Diagnosis of Potential Research Subjects with Nystagmus or Strabismus

Screening Study for the Evaluation and Diagnosis of Potential Research Subjects with Retinovascular Diseases

Screening Study for the Evaluation and Diagnosis of Potential Research Subjects with Inherited Ophthalmic Diseases

A Study of Crystalline Proteins in Young Normal Lenses Using the NASA-NEI Dynamic Light Scattering (DLS) Device

The Vitreous Proteome and inflammatory Mediators in Ocular Inflammatory Disease

Evaluation and Treatment Protocol for Patients with Intraocular Inflammatory Disease (Uveitis)

Age-Related Eye Disease Study - Phase II

Trial of Treatment of Non-Infectious Intermediate and Posterior Uveitis with Humanized Anti-Tac Antibody Therapy

Visual Motor Coordination in Man

Trial of Topical Cysteamine in the Treatment of Corneal Cystine Crystal Accumulation in Cystinosis

Treatment of Choroidal Subretinal Neovascularization with Agents Directed Against the Immune Response

Pathogenesis of Focal Segmental Glomerulosclerosis

A Phase II Study of OT-551 Antioxidant Eye Drop in Participation with Bilateral Geographic Atrophy Associated with Age-Related Macular Degeneration

Immunopathology of Ocular Disease in Humans

Top-Down Attentional Control of Visual Processing

Familial Exudative Vitreoretinopathy Clinical and Molecular Studies

Digital Image Based Determination of Ocular Surface Vital Dye Staining

Daclizumab for Active, Non-infectious, Sight-threatening Uveitis: A Phase II Pilot Study

Phase I Study of Intravitreal Injections Versus Anterior Sub-Tenon Injections of Triamcinolone Acetonide Formulation for Macular Edema in Retinal Disorders

Identification of Biological Markers in Retinal Vasculitis

Combination Daclizumab/Sirolimus Therapy For the Induction of Immune Tolerance in Non-Infectious Intermediate and Posterior Uveitis

Pilot Study of Intravitreal Injection of Triamcinolone Acetonide Formulation for Retinal Vascular Disorders

Treatment of Non-Infectious Intermediate and Posterior Uveitis Associated Macular Edema with Humanized Anti-CD11a Antibody Therapy

A Pilot Study of Laser Photocoagulation for Diabetic Macular Edema

Systemic Immunosupressive Therapy for Eye Diseases (SITE) Cohort Study

Prevalence and Risks for Posterior Subcapsular Cataracts in Volunteer Granulocytapheresis Donors

Pilot Study on the Effect of Vitamin A Supplementation on Cone Function in Retinitis Pigmentosa

Treatment of Active Anterior Uveitis Associated with JIA, Using Humanized Anti-Tac (HAT, Daclizumab)

Evaluation of Infliximab in the Treatment of Non-Infectious Scleritis

X-Linked Juvenile Retinoschisis - Clinical and Mocular Studies

A Case Control Study of Age-Related Macular Degeneration (AMD) Examining Gene Expression Patterns in Circulating Monocytes from Peripheral Blood Samples

Analysis of Differential Gene Expression Profiles in Patients with Defined Ocular Inflammatory Diseases Using CDNA Microarrays and Proteomics

Evaluation of Immune Responses to Different Antigens in Non Infectious Ocular Inflammatory Diseases

Clinical and Molecular Studies in Families With Corneal Dystrophy or Other Inherited Corneal Diseases

Family Studies of Uveal Coloboma

Clinical and Molecular Studiies in Familes with Congenital or Hereditary Cataracts

Pilot Study on the Use of the NASA-NEI Dynamic Light Scattering (DLS) Device in Detecting lens Changes in the other Eye of Patients with Pre-Senile Cataracts

A Phase I/II Randomized, Controlled Study of OGT 918 in Adult and Juvenile Patients with Niemann Pick C Disease

Evaluation and Treatment of Pediatric, Developmental and Genetic Eye Disease

Investigation of the Dietary Docosahexaenoic Acid (DHA) Supplementation on Macular Function in Subjects with Autosomal Dominant Stargardt-Like and Autosomal Recessive Stargardt Macular Dystrophy

Evaluation and Treatment of Ocular Complications of Vaccinia Vaccination: Suitability of NP-016 Vaccinia Immune Globulin (VIG) for Sight-Threatening Conditions [VIG31]

A Multi-Center, Phase I Clinical Trial to Study the Safety of a Sustained-Release Subconjunctival Cyclosporine Implant for Ocular Graft-vs-Host Disease

Combination Daclizumab/Denileukin Diftitox (Ontak) Therapy for the Induction of Immune Tolerance in Non-infectious Intermediate and Posterior Uveitis

Multi-Center, Randomized, Phase II/III Clinical Trial to Study the Effects of Preservative-Free Triamcinolone Acetonide as an Adjunct to Photodynamic Therapy in Participants with Neovascular Age-Related Macular Degeneration

Evaluation of Single Nucleotide Polymorphism (SNP) in Patients with and Subjects without Age-Related Macular Degeneration (AMD)

Last updated: September 15, 2006 at 4:30:37 PM