NIH Studies: Neurology

Below is a listing of government-funded clinical trials in Neurology, being conducted by the various National Institutes of Health at the Warren Grant Magnuson Clinical Center in Bethesda, MD.

Click on a study summary to view the study description and contact information directly from the NIH's web site.

Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Controls

Evaluation of Density and Pattern of Distribution of GABA Receptors in the Brain of Patients with Focal Hand Dystonia Studied with PET using [11C] Flumazenil

Long-Term Improvement in Training Effects by Transcranial DC Stimulation

Treatment for Psychogenic Movement Disorders

Direct Convection-Enhanced Delivery of Glucocerebrosidase for the Treatment of Type 2 (Acute Neuronopathic) Gaucher Disease

The Treatment of Menstrually-Related Mood Disorders with the Gonadotropin Releasing Hormone (GnRH) Agonist, Depot Leuprolide Acetate (Lupron)

fMRI Studies of Task Specificity in Focal Hand Dystonia

Moving a Paralyzed Hand Through a Brain-Computer Interface Controlled by the Affected Hemisphere After Stroke

Neuropsychological Evaluation of Psychiatric and Neurological Patients

PET Whole Body Biodistribution and Test Retest Brain Imaging Studies Using a Phosphodiesterase 4 Inhibitor (R)-[11C]rolipram

PET Imaging of GABA Receptors in Succinic Semialdehyde Dehydrogenase Deficiency

Identifying the Role of Oxytocin and Vasopressin in the Functioning of Neurocognitive Systems Involved in Mood Disorders

Encoding a Motor Memory by Action Observation

Structural and Functional Imaging of Neuropsychiatric Patients and Normal Volunteers with 3.0 Tesla MRI

Cortical Function in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis

Encoding a Motor Memory Through Metaplasticity

Intraspinal Plasticity Associated with Locomotor Learning

Repetitive Transcranial Magnetic Stimulation Studies of Visual Attention

Non-Invasive Seizure Localization in Patients with Medically Refractory Localization Related Epilepsy: Synchronized MEG-EEG Recordings

Zenapax (daclizumab) Administered to Patients with Multiple Sclerosis (ZAP MS)

MRI in Autosomal Dominant Partial Epilepsy with Auditory Features

Development of 7 Tesla MRI Methodology for Anatomical Functional and Spectroscopic Imaging of the Brain

Identification of Hereditary Auditory Temporal Processing Deficits

Spinal Substrates of Training-Dependent Improvements in Locomotor Function

Genetic Studies of Tune Deafness

SMN Levels in Peripheral Blood Samples of SMA Patients and the Effects of Pharmacological Compounds In Vitro

Social Knowledge Representation in the Human Prefrontal Cortex

Reperfusion of Stroke Safety Study Imaging Evaluation-2(ROSIE 2) Adjunctive Treatment to Standard Alteplase Therapy of ischemic Stroke

Evaluation and Treatment of Neurosurgical Disorders

Improvement of Motor Learning in Chronic Stroke Patients By Transcranial DC Stimulation

Event-Related fMRI Analysis of Patients with Ideomotor Apraxia During Transitive and Intransitive Hand Gesturing

Remote Effects of Stroke on Cerebral Metabolism. Evaluation with Positron Emission Tomography and Proton Magnetic Resonance Spectroscopy

Integrating EEG and fMRI: Tonic and Phasic Activity Correlation of Hippocampal/Prefrontal (Theta)-Activity During Cognitive Activation in Schizophrenic Patients and Unaffected Siblings

Structural and Functional Imaging of Neuropsychiatric Patients and Normal Volunteers with 1.5 Tesla MRI

Gene Analysis in Parkinson's Disease

Genetic Analysis of Parkinson's Disease

Regional Cerebral Blood Flow Studies of Object Perception, Identification, Localization, and Memory

Long-Term Motor Learning in Focal Hand Dystonia

The Central Nervous System Effects of Pharmacologically Induced Hypogonadotropic Hypogonadism with and without Estrogen and Progesterone Replacement

Plasticity in Cervical Dystonia

An Exploratory Study on Detection of Cortical and White Matter Damage in Patients with Multiple Sclerosis Using Magnetic Resonance Imaging at 7 Tesla

Direct Current Brain Polarization for Apraxia in Corticobasal Syndrome

The Effects of an NMDA-Receptor Antagonist in Idiopathic Voice Disorders

NINDS Biomarkers in Multiple Sclerosis Study (BioMS)

Bioenergetic Function in Parkinson's Disease

Anomalous Ipsilateral Corticofugal Projections in Children with Cerebral Palsy

Changes in Intracortical Inhibitory Processes are Associated With the Development of Implicit Learning of a Motor Task

Examining Associative Relations in Structured Event Complexes Using Functional Neuroimaging

Modulation of the Visual Information Processing in the Human Parieto-Frontal Network as Studied by a Frequency Tagging Technique During Visuomotor Tracking

Neurophysiological Studies in Patients With Paroxysmal Hyperkinetic Movement Disorders

Mechanisms of Training Induced Improvements in Gait Function After Stroke

Spatiotemporal Dynamics of Cortical Connectivity Involved in Tics and Voluntary Movements in Patients With Tourette's Syndrome and Chronic Motor Tic Disorder: An EEG Study

Registry of Fabry Disease: A Multicenter, Longitudinal Observational Study

PET Scanning in Parkinson's Disease

Testing Objective Measures of Motor Impairment in Early Parkinson(s) Disease

Neuropathological Basis of Spasmodic Dysphonia

Plasma Exchange for Autoimmune Autonomic Failure

A Comparison of an Implanted Neuroprosthesis with Sensory Training for Improving Airway Protection in Chronic Dysphagia

Collection of Blood Samples for DNA Analysis in Motor Neuron Diseases

Cognitive Function in Parkinson's Disease: Relationship to Cortical Dopamine Synthesis and Dopamine D1 Receptors

Influencing Motor Performance in Patients with Stroke by Combined Theta Burst Stimulation and Carbidopa-Levodopa

Effects of Unilateral and Bilateral Training on Motor Function in Chronic Stroke

PET Imaging of Brain Peripheral Type Benzodiazepine Receptors

Blepharospasm and the Experimental Modulation of Cortical Excitability in Primary and Secondary Motor Areas. A Pilot Study.

Brain Networks Responsible for Sense of Agency: An EEG Study

Evaluation of the Mechanism of NO Formation and Pharmacokinetics of Long-Term Intravenous Nitrite Infusion in Healthy Volunteers

Neural Correlates of Observational Motor Learning in Chronic Stroke Patients

MR and Recanalization of Stroke Clots Using Embolectomy (MR Rescue)

Interhemispheric Plasticity in Humans

Enhancement of Rehabilitative Treatment-Dependent Functional Recovery After Stroke by Transcranial Direct Current Stimulation (tDCS)

Placebo Controlled Study of the Therapeutic Effect of the Transcranial Electrical Polarization in Patients with Focal Hand Dystonia

The Role of the Orexin System in Body Weight Regulation: Patients with Narcolepsy

Neurotropin for Acute Dental Pain and for Chronic Neuropathic Pain

Investigating the Neuro-cognitive Underpinnings of the Emotional Dysfunction Linked to Childhood Behavioral Disturbance

Effects of Sleep Deprivation and Recovery Sleep on Speech, Language and Other Higher Cognitive Functions: A Combined EEG-fMRI Study

Brain Connectivity between Visual Input and Motor Output

Clinical Trial Characterizing the Pharmacokinetics of 1-Octanol in Adults with Essential Tremor

Impaired Motor Learning and LTP/LTD-like Plasticity in Dystonia, are Associated with Abnormal Modulation of Cortical Excitability by Somatosensory Volleys

MEG Study of Altered Sensory Processing in Tourette Syndrome: An Exploration of Sensory Tics

Contribution of Interhemispheric Inhibition to Motor Learning

Genetic Basis For Variation In NSAID Analgesia In A Clinical Model Of Acute Pain

Towards the Establishment of Standards of Practice and the Initiation of Multi-Center, Multi-National Clinical Trials for Neonates and Children With Stroke

The Effect of Surround Inhibition during Phasic compared to Tonic Voluntary Finger Movement in Focal Hand Dystonia

Hypersensitivity in Tourette Syndrome: An Evaluation of Perceived Intensity Versus Threshold

Hypertonia in Patients with Cerebral Palsy

MRI Measurement of Brain Metabolism Across the Sleep-Wake Cycle

Recombinant Human Interferon Beta-1a in Acute Ischemic Stroke: A Dose Escalation and Safety Study

An Exploratory Study on Detection of Cortical Damage in Patients with Multiple Sclerosis Using Magnetic Resonance Imaging

Role of the Parieto-Frontal Network in Automatic Processing of Visually Presented Objects

The Role of Cortical Coherence in Focal Hand Dystonia

Clinical Neurophysiology: Training and Normative Values

Functional MRI (fMRI) and Diffusion Tensor Imaging (DTI) in Temporal Lobe Epilepsy

Central Motor Physiology in Polio Survivors

Physiology of Weakness with Movement Disorders

Treatment Study for Frontotemporal Dementia

Neural Modeling and Brain Imaging of Tinnitus

Studies of Frontal Lobe Function During Cognitive Stimulation as Measured with Oxygen-15 Water Positron Emission Tomography (PET) in Normal Subjects and Neuropsychiatric Patients

Repetitive Transcranial Magnetic Stimulation in Chronic Stroke Patients. Dose Effect on Motor Cortex Excitability, Motor Performance, and Safety Using Different Stimulation Parameters.

Implicit Tactile Learning in Chronic Stroke Enhanced by Non-Invasive Brain Stimulation of the Somatosensory Cortex

Neurophysiology of Task-Specificity of Focal Hand Dystonia

Brain Procurement for the Neuropathology Section, CBDB

Modulation of Motor Learning After Stroke Using Principles of Metaplasticity

Cortical Excitability in Succinic Semialdehyde Dehydrogenase Deficiency

Improvement of Motor Performance in Chronic Stroke Patients by Combined Transcranial DC Stimulation and Somatosensory Stimulation

Pilot Study of Cystagon as a Potential Therapy for Infantile Neuronal Ceroid Lipofuscinosis

Timing of Voluntary Movement in Patients With Tourette Syndrome and Chronic Tic Disorder Using EEG and Surface EMG

Anticonvulsive Effects of Transcranial DC Stimulation in Pharmacoresistant Temporal Lobe Epilepsy

Safety Study of the Super Rapid Transcranial Magnetic Stimulation in Patients with Parkinson's Disease

Induction of Volitional Swallowing in Chronic Dysphagia Post Stroke: A Novel Mechanism - Based Intervention

Phase II Clinical Trial to Examine the Efficacy and Safety of Dutasteride in Patients With Kennedy's Disease (Spinal and Bulbar Muscular Atrophy)

Role of Ventral Premotor Cortex in Recovery of Motor Function in Chronic Stroke

Neurophysiological Markers in Patients with Craniofacial Dystonia and Their Relatives

Transcranial Electrical Polarization for the Treatment of Bradykinesia and Rigidity in Patients with Parkinson's Disease.

fMRI Study on Mechanism of Rhythm Perception and Generation

Last updated: September 15, 2006 at 4:30:37 PM