The following information is obtained from various newswires,
published medical journal articles, and medical conference presentations.
Company: Braintree Laboratories
Approval Status: Approved April 2001
Treatment for: Hyperphosphetemia
General Information
PhosLo, in both capsule and gelcap formulations, has been approved for the control of hyperphosphatemia in end stage renal failure in adult patients. Patients suffering from kidney disease may experience increased blood levels of phosphate, which plays a pivotal role in causing secondary hyperpara-thyroidism associated with osteodystrophy and soft-tissue calcification. The rate of removal of phosphate by dialysis or by dietary manipulation is insufficient.
Clinical Results
Studies have confirmed that using calcium acetate as a phosphorus binder will control serum phosphorus levels in most dialysis outpatients.
Side Effects
Adverse events associated with the use of PhosLo capsules or gelcaps may include (but are not limited to) the following:
- Nausea
- Constipation
- Vomiting
- Stomach pains
- Anorexia
Mechanism of Action
PhosLo (calcium acetate) binds to the phosphate taken in through one's diet to form insoluble calcium phosphate. This is then excreted from the body without being absorbed.
Additional Information
For additional information on PhosLo, please visit Braintree Laboratories.
