The following information is obtained from various newswires,
published medical journal articles, and medical conference presentations.
Company: Roche
Approval Status: Approved August 1998
Treatment for: Depression
General Information
Marplan is indicated for the treatment of depression. Because of its potentially serious side effects, it is not recommended as an anti-depressant of first choice in the treatment of newly diagnosed depressed patients.
The effectiveness of Marplan for long-term use, meaning longer than 6 weeks, has not been fully evaluated by trials.
Side Effects
Marplan can cause serious side effects. It is not recommended as initial therapy but should be reserved for patients who have not responded satisfactorily to other anti-depressants.
Some side effects include: headaches, palpitation, neck stiffness, nausea or vomiting, sweating (fevers or clammy skin), photophobia, tachycardia, bradycardia, constricting chest pain, dilated pupils, intracranial bleeding and increased blood pressure.
