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Research Center Profile:
The Program in Novel Therapeutics, NS-LIJ Health System

Center Information

Richard Furie, M.D.
Director, The Program in Novel Therapeutics
The Program in Novel Therapeutics, NS-LIJ Health System
Division of Rheumatology and Allergy-Clinical Immunology
North Shore-Long Island Jewish Health System
2800 Marcus Avenue, Suite 200
Lake Success, NY 11042
USA
516-708-2556
516-708-2574 (fax)
furie@nshs.edu
www.northshorelij.edu
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Contact Center

Therapeutic Areas

Dermatology
Endocrinology
Immunology
Musculoskeletal
Nephrology
Rheumatology

Center Overview

North Shore-Long Island Jewish Health System, one of the largest integrated health care systems in the United States, provides medical coverage for patients in five counties. At the hub of the 15 hospital System is North Shore University Hospital, a 744 bed hospital with an academic affiliation to New York University School of Medicine, and Long Island Jewish Hospital with an academic affiliation to the Albert Einstein College of Medicine. The Program in Novel Therapeutics was established in 1990 to foster clinical research in the area of new drug development for musculoskeletal and autoimmune diseases. This Center specializes in basic and clinical investigation in the areas of rheumatoid arthritis, osteoarthritis, systemic lupus erythematosus, lymphocyte biology, autoimmunity, metabolic bone disease, cartilage transplantation, and molecular genetics. Facilities include an outpatient as well as an inpatient clinical research unit for phase I-IV studies.

Clinical Research Experience

The Program in Novel Therapeutics has performed over 70 phase I-IV studies with a variety of sponsors.

Our Program has performed studies with drugs and biologics in the following disease categories:

  • Antiphospholipid Antibody Syndrome
  • Back Pain
  • Common Variable Immune Deficiency
  • Dermatomyositis
  • Genetics
  • Gout
  • Inflammatory Arthritis
  • Juvenile Rheumatoid Arthritis
  • Lupus Nephritis
  • Membranous Nephropathy
  • Osteoporosis
  • Polymyositis
  • Pulmonary Arterial Hypertension
  • Psoriasis
  • Psoriatic Arthritis
  • Rheumatoid Arthritis
  • Scleroderma
  • Systemic Lupus Erythematosus

Facility Description

The Program in Novel Therapeutics is based in the Division of Rheumatology at the North Shore-Long Island Jewish Health System in Lake Success, New York. Investigators span many facilities of the North Shore-Long Island Jewish Health System, including North Shore University Hospital, Long Island Jewish Hospital, Schneider Children's Hospital, and the Feinstein Institute for Medical Research. Because the Program is located in one of the most densely populated areas of the country and draws from a population of over five million, patient enrollment for study protocols has been excellent. Patient recruitment has also been enhanced by a computerized database; which currently contains 45,000 patients and is growing at a rate of 2,000 patients per year. Other facilities include: a 6 bed unit devoted to infusional therapy, a gene therapy unit, musculoskeletal ultrasound, magnetic resonance imaging (MRI), positron emission tomography (PET), skeletal radiology, minus seventy degree freezers, a bone densitometer (Hologic), and an on-site IRB. The immunology research laboratories, which house technology to perform basic serologic tests, PCR, HLA typing, flow cytometry, DNA sequencing, peptide sequencing and synthesis, and high throughput genotyping expression analysis using DNA microchip arrays, are available for those protocols requiring specialized in vitro work. Utilizing rodent models of arthritis, this facility can perform pre-clinical evaluation of agents in development for rheumatoid and other types of inflammatory arthritis.

Investigator Experience

CLINICAL INVESTIGATORS

Rheumatology
Richard Furie, M.D.
Director, The Program in Novel Therapeutics and Chief, Division of Rheumatology and Allergy-Clinical Immunology, North Shore-Long Island Jewish Health System
Professor of Clinical Medicine,
Albert Einstein College of Medicine
Director,The SLE and Autoimmune Disease Treatment Center
Director,Fellowship Program

Avram Goldberg, M.D.
Director, The Scleroderma Treatment Center
Assistant Professor of Medicine,
Albert Einstein College of Medicine

Maria-Louise Barilla-LaBarca, M.D.
Assistant Professor of Medicine,
Director, Housestaff and Medical Student Education Program
Director, Fellowship Program

Robert Greenwald, M.D.
Associate Chairman of Medicine for Academic Affairs

Galina Marder, M.D.
Director, Inflammatory Muscle Disease and Vasculitis Center
Assistant Professor of Medicine,
Albert Einstein College of Medicine

Pediatric Rheumatology
Beth Gottlieb, M.D.
Chief, Pediatric Rheumatology, Schneider Children's Hospital

Anne Eberhard, MB FRACP
Chief, Pediatric Rheumatology, Schneider Children's Hospital at North Shore University Hospital

Lilliana Barillas-Arias, MD
Scheider Children's Hospital

Metabolic Bone Disease
Stuart Weinerman, M.D.
Director, Metabolic Bone Disease Program
Biostatistics
Martin Lesser, Ph.D.
Director, Division of Biostatistics, North Shore-Long Island Jewish Health System Research Institute
Clinical Research Coordinators
Laura Donohue, C.C.R.C.
Senior Research Coordinator
Certified Clinical Research Coordinator

Michelle Kong - Rosario
Research Coordinator

Donna Ammirati
Research Coordinator

Rachel Saltzman
Research Coordinator

Center for Infusion Therapy
Ann McCally, R.N.
Director, Center for Infusion Therapy

Patricia Dean, R.N.
Infusion Nurse Specialist

Allison Venuto, R.N.
Infusion Nurse Specialist

BASIC INVESTIGATORS

Nicholas Chiorazzi, M.D.
Director, Chronic Lymphocytic Leukemia Research Program

Charles Chu, Ph.D.
Director, Laboratory of Lymphocyte Biology

Daniel Grande, Ph.D.
Director, Cartilage Biology Research

Peter Gregersen, M.D.
Chief, Division of Human Biology and Genetics

Percio S. Gulko M.D.
Director, Laboratory of Experimental Rheumatology, Center for Genomics and Human Genetics

Kevin Tracey, M.D.
Director and Chief Executive Officer, The Feinstein Institute of Medical Research

INVESTIGATIVE PHARMACISTS

Norberto Collado, R.Ph.
Research Pharmacist

ADMINISTRATOR

Laura Hanna
Administrative Secretary

Other Information

Currently Enrolling patients with the following medical conditions into clinical trials:

PLEASE CALL THE PHONE NUMBER BELOW FOR MORE INFORMATION:

  • Dermatomyositis
  • Genetics
  • Lupus Nephritis
  • Osteoarthritis
  • Polymyositis
  • Psoriatic Arthritis
  • Rheumatoid Arthritis
  • Scleroderma
  • Systemic Lupus
  • Vasculitis

Contact Center

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