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Research Center Profile:
John Muir Physician Network Clinical Research Center

Center Information

Teri Considine
John Muir Physician Network Clinical Research Center
2700 Grant St, Suite 200 (2nd Floor)
Concord, CA 94520
925-687-1570 (fax)
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Therapeutic Areas

Cardiology/Vascular Diseases
Nutrition and Weight Loss

Center Overview

John Muir Physician Network Clinical Research Center is a dedicated clinical research center, established in 1985 under the leadership of its' principal investigator Roy A. Kaplan, MD. Dr. Kaplan has more than 30 years of extensive experience in endocrinology, metabolism, and internal medicine as a private physician as well as 20+ years of clinical research experience.

John Muir Physician Network Clinical Research Center is owned and operated by John Muir Health, an integrated health delivery system consisting of two acute hospitals, a trauma center, an inpatient and outpatient mental health facility, a skilled nursing facility and a network of over 600 primary care physicians and specialists. John Muir Physician Network Clinical Research Center also employs the services of sub-investigators in various specialties, including gastroenterologists, neurologists, cardiologists, psychiatrists, allergists, rheumatologists, ophthalmologists, dermatologists, and several internal medicine and family practice physicians. Our Assistant Medical Director, Anna Chang, MD, CPI has clinical expertise in the treatment of Diabetes and Thyroid Disease.

Clinical Research Experience

John Muir Physician network Clinical Research Centerrecruits, manages and executes clinical research protocols for the pharmaceutical and biotechnological industry focusing on Phase II, III and IV trials. We have provided quality clinical trial services for the following sponsors and clinical research organizations:

Abbott, Advanced Biologics, Alpha, Alteon, Amira, Amgen, Amylin, Arena, ArKal, Astra Zenica, Bayer, Besselaar, Biodel, Boehringer Ingelheim, Bristol Meyers Squibb, Dalichi Sankyo, Dexcom, Cygnus, Cholestech, Ciba Geigy, Covalent, Eli Lilly, Forest, Glaxo Smith Kline, Genetech, Genomics, Generex, Halozyme, Hoechst Marion Roussel, Hoffman La-Roche, Ingenix, Johnson and Johnson, Lifescan, Keryx, Kendal, Kos, Magainin, Medex, MEC Dynamics, MDS Pharma, Medpace, Merck, Novartis, Novo Nordisk, NPS-Allelix, Ominicare, Ortho-Biotech, Ortho-McNeil, Otsuka, Paraxel, Parke-Davis, Pfizer, Pharmacia, Pharmaceutical Research Institute, PPD, Proctor & Gamble, Provalis, Quintiles, Regeneron, Rhythm, Roche, Sangamo, Sankyo, Sanofi Aventis, Schering-Plough, Schwarz Biosciences, Searle, Smith Kline Beecham, Solvay, Takeda Of America, Tandem, TAP, Telios.

The treatment of diabetes mellitus--its monitoring as well as the treatment and prevention of diabetic complications--has been the major focus of our research. However, with the integration of our program into a 164 -provider primary care group and hospitalists we are able to expand into the following therapeutic areas: Anxiety, asthma, atrial fibrillation, congestive heart failure, depression, gastroesophageal reflux, hormone replacement therapy, hyperlipidemia, hypercholesterolemia, hypertension, impotence, irritable bowel syndrome, migraine headaches, obesity, osteoarthritis, osteoporosis, Parkinsons' Disease, sinusitis, smoking cessation and several device studies.

John Muir Physician Network Clinical Research Center has conducted the following clinical trials:

  • Asthma
  • Cardiovascular Disease
  • Diabetes Mellitus - Type 1 and Type 2
    • Inhaled Insulin
    • Nephropathy
    • Neuropathy
    • Hypertension
    • Foot Ulcers
    • Glucose Monitoring
    • Glucose Sensors
  • Obesity / Weight Loss
  • Depression
  • Gastrointestinal
    • Irritable Bowel Syndrome
    • Gastroesophageal reflux (GERD)
    • Gastroparesis
    • Hypertension
  • Hyperlipidemia
  • Hypercholesterolemia
  • Osteoporosis
  • Osteoarthritis
  • Smoking Cessation
  • Cold and Influenza
  • Adult Growth Hormone Deficiency
  • Erectile Dysfunction
  • Pharmokinetics Testing
  • Parkinson's Disease
  • Prostate Cancer Prevention
  • Urinary Incontinence (Women)
  • Medical Device Studies

Facility Description

The office of John Muir Physician Network Clinical Research Center occupies 3200 square feet in a medical building adjacent to John Muir Medical Center, Concord Campus in Concord, California. The office is 42 miles from the San Francisco Airport, 32 miles from the Oakland Airport and 73 miles from the Sacramento Airport. We are convenient to Bay Area Rapid Transit and are located on the local bus route.

Our facilities are pleasant and comfortable and are equipped with the following state-of-the-art medical equipment:

  • Lab, fully equipped for specimen processing
  • Refrigerated centrifuge
  • -20° C freezer
  • Locked ambient and temperature controlled drug storage: monitored continuously and recorded daily in temp log book.
  • Bayer HGbA1c analyzersElectrocardiogram machines
  • Stress-Treadmill
  • DXA Bone Densitometry Machine
  • Mammography in two locations
  • X-Ray facilities (in 4 locations)
  • MRI
  • Monitor space, 3 separate offices fully equipped with phone and internet
  • Conference Room
  • Patient lounge/ Kitchen and Meal Testing area
  • Back up Generator
  • Secure Off Site Record storage

We are affiliated with the John Muir Health System which consists of two acute hospitals. Our main focus is outpatient and device studies.

Investigator Experience

Roy A. Kaplan, MD, Co-Medical Director
Dr. Kaplan has been involved in clinical trials since 1973 and has acted as principal investigator in more than 250 protocols.

Dr. Kaplan has more than 30 years of extensive experience in endocrinology, metabolism and internal medicine as a private practice physician, as well as his 20+ years of experience as principal investigator in clinical trials.

Anna Chang, MD, CPI serves as Co-Medical Director
Principal Investigator on most of our clinical trials and a Sub-Investigator on other trials.

Douglas Zlock, MD specialist in Endocrinology
Serves as Sub-Investigator on our clinical trials.

Genevieve Yue, MD specialist in Endocrinology
Serves as Sub-Investigator on our clinical trials.

Staff Expertise

John Muir Physician Network Clinical Research Center currently employs a principal investigator, several sub-investigators and 7staff members. They also contract with other specialty physicians to serve as principal investigators in clinical trials.

Roy A. Kaplan, MD serves as the Medical Director and also as the Principal Investigator.

Staff members include a site manager with 12 years of research experience, regulatory specialist with 10 years of research experience and 5 registered nurses with 10-30 years of nursing and research experience. Two CDE’s. Add A Registered Dietician, MPH.

Patient Demographics

John Muir Physician Network Clinical Research Center is located in Concord, California midway between the San Francisco and Sacramento International Airports. Concord is part of Contra Costa County the ninth most populous county in the state. Contra Costa County has approximately 51,000 persons with diabetes mellitus. The Center has access to a demographically diverse patient population of over 1,121,000 residents in the county and also over 120,000 residents of Southern Solano County. Ethnic makeup is Caucasian, African American, Hispanic, Asian and Native American. The site has a database of over 310,000 patients through their association with John Muir Health and an additional database of their own of over 7,500 patients.

Other Information

Our site uses a central IRB for the majority of our trials. We are experienced with remote data entry in many clinical trials.

Contact Center

If you are interested in contacting this center to discuss placing a clinical trial there, please complete and send the email form below. A representative from the research center will then follow up with you.

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