Skip Navigation



Home » Industry News and Resources » Research Centers

Research Center Profile:
Midwest Chest Consultants, PC

Therapeutic Areas

Cardiology/Vascular Diseases
Internal Medicine
Nutrition and Weight Loss
Pulmonary/Respiratory Diseases

Center Overview

Midwest Chest Consultants, PC is a private office based medical practice specializing in pulmonary, critical care and sleep medicine. There are 2 pulmonologists based in the practice, located in St. Charles, MO. We have conducted clinical research since 1990.

Clinical Research Experience

Our facility specializes in pulmonary and sleep medicine related clinical research activities. We have worked with numerous major pharmaceutical companies and several CRO's performing phase II, III and IV studies. Trials have been conducted in COPD, asthma, AECB, atrial fibrillation, DVT/PE, pneumonia, obesity, and nocturnal hypoxemia. We have also performed phase IIIb studies.

Facility Description

Our office conducts inpatient and outpatient based clinical trials. Full pulmonary medicine facilities are available in our office including complete PFT's, exercise physiology testing, ECG, Holter monitoring, serial spirometry, serial PK's, oxygen saturation measurements, six-minute walk testing, shuttle walk testing, and phlebotomy. We are also capable of outpatient infusion trials. The adjacent hospital has full radiology facilities (including high-resolution CT scanning), exercise physiology lab and 6-bed AASM accredited sleep lab with paper recording capability on two of six beds.

Investigator Experience

Thomas M. Siler, MD is board certified in Internal Medicine, Pulmonary Diseases and Sleep Medicine. He has conducted clinical research in his practice since 1990 in both inpatient and outpatient studies. He has been principal investigator in over 120 trials. He has attended IRB sponsored GCP training. Subinvestigators include Frank Calandrino, MD, Susan Iffrig APRN, Stacey Brown APRN, V. Christine Champagne APRN, CCRC, and Jill Fritz, APRN.

Staff Expertise

Mitchell Champagne, RPh, CCRC is director of research. He has conducted numerous clinical research trials since 1997.

Marcia Gaddy, RN, CCRC is a study coordinator. She has conducted clinical research since 1999.

Billie Greenwell, RN, CCRC is a study coordinator. She has conducted clinical research since 2002.

Krista Haggard, RMA CCRC has been involved in healthcare in our office since 1993

Kasey Seyer, B.S., CCRC is a study coordinator. She has conducted clinical research since 2006.

Patient Demographics

Adult subjects with lung and sleep disorders are available through our private practice. We have more than 6,000 active patients in our practice. We also have access to subjects throughout the St. Louis metropolitan area with a population of over 2 million. We have arrangements for local lodging nearby for accommodating patients requiring long study visits who live outside our immediate area.

Other Information

We can use central IRB's for outpatient studies. For inpatient studies, our adjacent hospital has a very proactive IRB that meets on a regular basis with decisions concerning approval of protocols made in a reasonable period of time.

Contact Center

If you are interested in contacting this center to discuss placing a clinical trial there, please complete and send the email form below. A representative from the research center will then follow up with you.

Zip/Postal Code:
Please leave this field empty.