The University of Kentucky Chandler Medical Center (UKCMC) is one the nation’s finest academic health care
centers. Its vision is to be a Top-20 academic health center recognized nationally and internationally for
excellence in teaching, research and patient care. Top 10 Business Plan
The University of Kentucky is achieving outstanding success in the competitive arena of research grants &
contracts (see Research statistics and national
rankings). Major research areas include Aging, Behavioral Health, Cancer, Drug Evaluation, Infection and
Immunity, Endocrinology, Gastroenterology, Surgery, Neurosciences, Spinal Cord Injuries, and Women's Health.
Center for Clinical and Translational Science (CCTS):
Established by the Board of Trustees as a University-wide center in September 2007, the Center for Clinical and
Translational Science (CCTS) at the University of Kentucky (UK) is leading the alignment of UK’s ongoing
transformation of its entire clinical and translational research enterprise with the goals of the NIH Roadmap
Clinical and Translational Science Award (CTSA). The overall goal of the CCTS is to accelerate the translation
of basic science advances to tangible improvements in the public’s health, addressed in three specific aims:
Specific Aim 1: Create an “academic home” for the discipline of clinical and translational
science through reconfigured and new infrastructure, core services, and key functions that both support and
operationalize research programs and initiatives; Specific Aim 2: Enhance outreach pathways to
confront chronic health issues in vulnerable and underserved rural communities; and Specific Aim
3: Grow the clinical and translational science research teams of the future through interlaced education
and training mechanisms designed to promote successful and productive careers in clinical and translational
science.
The CCTS now encompasses the Clinical Research Development and Operations Center (CR-DOC), which resulted from
the integration of the former UK Clinical Research Organization (UKCRO) and UK’s General Clinical Research Center
(GCRC). Along with eight other key functions, CR-DOC provides a centralized infrastructure consisting of key
core facilities and services to help investigators, clinicians, and scholars from across the University and the
Commonwealth of Kentucky to access much needed resources to become educated on the conduct of clinical research,
and to afford them mechanisms to access a gamut of support services needed for the conduct of high quality
clinical and translational research. These services do not end at the boundaries of the University of Kentucky
campus, but reach across the Commonwealth engaging greater partnership between the communities, industry, and the
University. Information on the CCTS Web site details the core facilities housed within the CCTS, with links to
other services. www.ccts.uky.edu
Highlights:
- Institutional IRB meets six (6) times each
month for rapid review and approval.
- Clinical Research Administrator
negotiates only clinical trial agreements.
- Clinical Research Development and
Operations Center (CR-DOC) provides administrative regulatory and/or operations support to investigators to
accelerate study initiation and coordination.
- Based on benchmarking data, study initiation averages 45 working days.
- Dedicated inpatient and outpatient research facilities.
- For Clinical Trial Volunteers
Website
- Faculty and staff are experienced in Phase I, II, III and IV clinical trials.
- Investigational Drug Service maintains a secure storage, dispensing and accountability system with service
available 24 hours per day.
- Clinical research faculty and staff complete mandatory trainings and are provided with numerous education
opportunities.
UKMC encompasses the following:
UKCMC also includes world-renowned centers:
Lexington Veterans Affairs Medical Center, (VAMC):
Many faculty members at UKCMC also maintain a joint appointment at the VAMC, expanding the potential research
subject base. (UKCMC and VAMC facilities are connected via a tunnel on the university campus).
The veteran population in Lexington's primary service area is estimated at more than 92,000 veteran.
- 199 acute care beds
- 61 nursing home beds
Patient at the VAMC in 2003:
- 249,907 outpatient visits
- 5,390 inpatient visits
Clinical Research Development and Operations Center (CR-DOC)
University of Kentucky Clinical Research Development and
Operations Center, (CR-DOC) was established to promote and expand the UKMC clinical research. The CR-DOC is
conveniently located in the Kentucky Clinic, which is adjacent to the University of Kentucky Hospital, this 3,985
square foot facility provides ample space to conduct outpatient trials and short-term pharmacokinetic studies. CR-DOC also occupies 4,344 square foot of space
in the newly remodeled Research Inpatient Clinic on the 5 floor of the hospital. These two centers along with the
Delta Dental of Kentucky Clinical Research Center (DDKCRC) will build on the past success to become all
encompassing service center -The Clinical Research Development and Operations Center (CR-DOC) through the Center
for Clinical Translational Science (CCTS). These facilities resources are available to all clinical investigators
throughout the University.
Services:
- To promote and facilitate clinical trials
- To provide regulatory and
administrative services
- To provide inpatient an outpatient coordination of all phase clinical trials
- Assist faculty and provide expertise in investigator initiated projects
- Improve and monitor clinical research compliance
- Provide clinical research
training and educational opportunities
Outpatient amenities include:
- Located on 1nd floor of the Kentucky Clinic Wing D L104
- 10,000 square feet of clinical research space
- Reception Area, nine exam rooms, and infusion rooms with three chairs
- Lab processing and shipping area
- Designated monitoring areas with remote computer connections
- Charting areas
- Conference Room, secured storage, and cold kitchen
Inpatient amenities include:
- Located on the 5th floor of the UKMC
- Fully staffed nursing unit
- 15- inpatient beds unit (8 rooms)
- Lab processing and shipping area
- Conference rooms
- Metabolic Kitchen
Biochemical Analysis Laboratory:
- Methodology consultation
- Performs assays not routinely available through the Hospital Clinical Laboratory, e.g. cytokines, growth
factors, hormones
- Capabilities to run assays on the Luminex, Affymetrix gene array, Immulite, chemiluminescence palte reader,
and endotoxin analysis
- /cap and CLIA accredited
- Networked with other laboratories greatly enhancing assay capability
Functional Assessment and Body Composition Core:
- Methodology consultation
- Exercise Physiolology lab (DEXA, BOD, POD, PFT, metabolic cart, GXT)
Delta Dental of Kentucky Clinical Research Center:
- 7,000 square feet of clinical research and laboratory space
- Three fully equipped dental examination room and four study coordinators
- Capability to analysis complex clinical, salivary microbiologic, and inflammatory markers of disease
- Three Spanish language interpreters; two bi-lingual recruiters/administrators
The University of Kentucky is centrally located in the scenic rolling hills of the Bluegrass.
(For descriptions, including photos, of some of UKCMC's facilities, see Facilities).
The Lexington, Kentucky campus includes:
Programs and Services
Travel and Lodging Information
Hotels
Lexington Convention and Visitors Bureau
301 East Vine Street
Lexington, Kentucky 40507
1-800-845-3959
(859) 233-7299
Metrotravelguide.com
www.metrotravelguide.com
Airport
Bluegrass Airport
4000 Versailles Road
859-425-3114
www.bluegrassairport.com
Taxicab
Yellow Cab Taxicabs
859-231-8294
Campus Guide
Campus Map
www.uky.edu/CampusGuide
The UK Medical Center is supported by more than 500 faculty physicians and dentists, 517 resident physicians and a staff of 3,200 health professionals committed to high-quality patient care. It has created an appealing environment to attract, reward and retain outstanding, multi-disciplinary clinical research personnel. Coordinator certification serves as a means of advancement. More than 75% of the currently employed Clinical Research Coordinators and Clinical Research Associates are certified, with many others in the process of obtaining certification. Proactive educational and training series are offered to ensure staff knowledge, skills and compliance with good clinical practice guidelines.
Kentucky has a population of 4,173,405. The UK Chandler Medical
Center provides health care to residents of all (120) Kentucky
counties and surrounding states,
(Kentucky and Regional Demographics). Much of
the regional area is rural and consists of stable, non-transient
people, with a high incidence of major chronic diseases. Patient
contacts for 1998 included more than 20,000 admissions, 35,000
emergency department visits, and 368,000 outpatient visits. Disease
demographics may be readily obtained for determination of potential
subject pools.
Lexington, KY Community Profile.
Kentucky is in the middle of the "Coronary Valley" - a
name given to areas with the highest rates of coronary heart
disease.
Kentucky’s ranking in disease areas in comparison to other states
in the nation:
- 27% of adult Kentuckians smoke (KY is ranked #1 in nation)
- 27% report no physical activities (#2)
- 33% report not using seat beats (#3)
- 38% are overweight; 24% are obese (#6)
- 9% of adults are diabetic (#7)
- 68% of individuals over the age of 65 are immunized (#11)
- Kentucky ranks 13th nationally in premature deaths
- 65% have a high school education (#14)
- Kentucky ranks 32nd nationally in the adequacy of prenatal care
- 27% of women who are pregnant continue to smoke while pregnant
- 43% of the 411 counties in the U.S. classified as high persistent poverty counties are located in Kentucky, all among the 51 counties in Kentucky that are located in Appalachian Eastern Kentucky.
- Cardiovascular disease in the leading cause of death in Kentucky
- 20 counties have Chronic Heart Disease mortality rates 25% higher than the national average
- Kentucky is ranked 3rd highest in cancer mortality rates
- Cancer rates for Incidence and Mortality by county (source 2007 Kentucky Cancer Registry)
- Kentucky is ranked 5th in the nation in deaths from coronary heart disease and overall cardiovascular disease
- Kentucky is ranked 6th as one of the nation’s worst location of allergies
- In most cases, serious health problems in Kentucky can be explained by its heavy smoking rate (one of the highest in the nation)
- Map of Adult Kentucky Illicit Drug Use Population
- Incidence of Mental stress, depression and emotional problems in the Adult Kentucky Population
University of Kentucky Chandler Medical Center
University of Kentucky Medical Center
C. William Balke, MD
Associate Provost
Director, Center for Clinical and Translational Science
Professor, Physiology and Medicine
University of Kentucky
740 South Limestone St., Wing D L104 KY Clinic
Lexington, Kentucky 40536-0284
Site Marketing Contact for Information
on Investigators and Research Studies:
Roxane L. Poskin
Manager, Participant Recruitment & Marketing
Lexington, KY 40536-0284
USA
Phone: 859-257-7856
Fax: 859-257-1563
EMail: Roxane.Poskin@uky.edu
Web Site: http://www.ukclinicalresearch.com
