Cardiology/Vascular Diseases
Dental and Oral Health
Dermatology
Endocrinology
Gastroenterology
Genetic Disease
Healthy Volunteers
Hematology
Hepatology (Liver, Pancreatic, Gall Bladder)
Immunology
Infections and Infectious Diseases
Internal Medicine
Musculoskeletal
Nephrology
Neurology
Nutrition and Weight Loss
Obstetrics/Gynecology (Women’s Health)
Oncology
Ophthalmology
Orthopedics/Orthopedic Surgery
Otolaryngology (Ear, Nose, Throat)
Pediatrics/Neonatology
Pharmacology/Toxicology
Plastic Surgery
Psychiatry/Psychology
Pulmonary/Respiratory Diseases
Rheumatology
Trauma (Emergency, Injury, Surgery)
Urology
Vaccines
The University of Kentucky Chandler Medical Center (UKCMC) is one the nation’s finest academic health care
centers. Its vision is to be a Top-20 academic health center recognized nationally and internationally for excellence in teaching, research and patient care - Top 10 Business Plan.
The University of Kentucky is achieving outstanding success in the competitive arena of research grants & contracts (see Research statistics and national rankings). Major research areas include Aging, Behavioral Health, Cancer, Drug Evaluation, Infection and
Immunity, Endocrinology, Gastroenterology, Surgery, Neurosciences, Spinal Cord Injuries, and Women's Health.
Center for Clinical and Translational Science (CCTS): Established by the Board of Trustees as a University-wide center in September 2007, the Center for Clinical and Translational Science (CCTS) at the University of Kentucky (UK) is leading the alignment of UK’s ongoing transformation of its entire clinical and translational research enterprise with the goals of the NIH Roadmap Clinical and Translational Science Award (CTSA). The overall goal of the CCTS is to accelerate the translation of basic science advances to tangible improvements in the public’s health, addressed in four specific aims:
Specific Aim 1: Enhance and develop new outreach pathways to confront chronic health issues in rural Appalachia, ensuring that our research addresses community concerns and that the community benefits from our findings.
Specific Aim 2: Develop the clinical and translational research programs of the future using innovative methods to champion collaborative team science.
Specific Aim 3: Enhance existing educational pathways and develop novel methods to educate and excite the next generation of collaborative clinical and translational scientists.
Specific Aim 4Strengthen the development of biomedical informatics and novel methodologies through improved cross-disciplinary collaboration.
The CCTS now encompasses the Clinical Research Development and Operations Center (CR-DOC), which resulted from the integration of the former UK Clinical Research Organization (UKCRO) and UK’s General Clinical Research Center
(GCRC). Along with eight other key functions, CR-DOC provides a centralized infrastructure consisting of key
core facilities and services to help investigators, clinicians, and scholars from across the University and the Commonwealth of Kentucky to access much needed resources to become educated on the conduct of clinical research, and to afford them mechanisms to access a gamut of support services needed for the conduct of high quality clinical and translational research. These services do not end at the boundaries of the University of Kentucky campus, but reach across the Commonwealth engaging greater partnership between the communities, industry, and the
University. Information on the CCTS Web site details the core facilities housed within the CCTS, with links to other services -www.ccts.uky.edu.
Highlights:
UKMC encompasses the following:
UKCMC also includes world-renowned centers
Clinical Research Development and Operations Center (CR-DOC)
University of Kentucky Clinical Research Development and Operations Center, (CR-DOC) was established to promote and expand the UKMC clinical research. The CR-DOC is conveniently located on the floor of UKMC, this 3,985 square foot facility provides ample space to conduct outpatient trials and short-term pharmacokinetic studies. (CR-DOC) also occupies 5,954 square foot of space in the newly remodeled Research Inpatient Clinic on the 5th floor of the hospital. These two centers along with the Delta Dental of Kentucky Clinical Research Center (DDKCRC) will build on the past success to become all encompassing service center -The Clinical Research Development and Operations Center (CR-DOC) through the Center for Clinical Translational Science (CCTS). These facilities resources are available to all clinical investigators throughout the University.
Services:
- To promote and facilitate clinical trials
- To provide regulatory and administrative services
- To provide inpatient an outpatient coordination of all phase clinical trials
- Assist faculty and provide expertise in investigator initiated projects
- Improve and monitor clinical research compliance
- Provide clinical research training
Outpatient amenities include:
- Located on 3rd floor of UKMC
- Reception Area, six exam rooms, and a procedure/phlebotomy room
- Lab processing and shipping area
- Designated monitoring areas with remote computer connections
- Charting areas
- Conference Room, secured storage, and cold kitchen
Inpatient amenities include:
- Located on the 5th floor of the UKMC
- Fully staffed nursing unit
- 15- inpatient beds unit (8 rooms)
- Lab processing and shipping area
- Conference rooms
- Metabolic Kitchen
Biochemical Analysis Laboratory:
- Methodology consultation
- Performs assays not routinely available through the Hospital Clinical Laboratory, e.g. cytokines, growth factors, hormones
- Capabilities to run assays on the Luminex, Affymetrix gene array, Immulite, chemiluminescence plate reader, and endotoxin analysis
- CAP and CLIA accredited
- Networked with other laboratories greatly enhancing assay capability
Functional Assessment and Body Composition Core:
- Methodology consultation
- Exercise Physiolology lab (DEXA, BodPod, PFT, metabolic cart, GXT, treadmill and bicycle ergometry, BIA)
Delta Dental of Kentucky Clinical Research Center:
- 7,000 square feet of clinical research and laboratory space
- Three fully equipped dental examination room and four study coordinators
- Capability to analysis complex clinical, salivary microbiologic, and inflammatory markers of disease
- Three Spanish language interpreters; two bi-lingual recruiters/administrators
The UK Medical Center is supported by more than 500 faculty physicians and dentists, 517 resident physicians and a staff of 3,200 health professionals committed to high-quality patient care. It has created an appealing environment to attract, reward and retain outstanding, multi-disciplinary clinical research personnel. Coordinator certification serves as a means of advancement. More than 75% of the currently employed Clinical Research Coordinators and Clinical Research Associates are certified, with many others in the process of obtaining certification. Proactive educational and training series are offered to ensure staff knowledge, skills and compliance with good clinical practice guidelines.
Kentucky has a population of 4,339,367. The UK Chandler Medical
Center provides health care to residents of all (120) Kentucky
counties and surrounding states,
(Kentucky and Regional Demographics). Much of
the regional area is rural and consists of stable, non-transient
people, with a high incidence of major chronic diseases. Patient
contacts for 1998 included more than 20,000 admissions, 35,000
emergency department visits, and 368,000 outpatient visits. Disease
demographics may be readily obtained for determination of potential
subject pools.
Lexington, KY Community Profile.
Kentucky is in the middle of the "Coronary Valley" - a
name given to areas with the highest rates of coronary heart
disease.
Kentucky’s ranking in disease areas in comparison to other states
in the nation:
- 27% of adult Kentuckians smoke (KY is ranked #1 in nation)
- 27% report no physical activities (#2)
- 33% report not using seat beats (#3)
- 38% are overweight; 24% are obese (#6)
- 9% of adults are diabetic (#7)
- 68% of individuals over the age of 65 are immunized (#11)
- Kentucky ranks 13th nationally in premature deaths
- 65% have a high school education (#14)
- Kentucky ranks 32nd nationally in the adequacy of prenatal care
- 27% of women who are pregnant continue to smoke while pregnant
- 43% of the 411 counties in the U.S. classified as high persistent poverty counties are located in Kentucky, all among the 51 counties in Kentucky that are located in Appalachian Eastern Kentucky.
- Cardiovascular disease in the leading cause of death in Kentucky
- 20 counties have Chronic Heart Disease mortality rates 25% higher than the national average
- Kentucky is ranked 3rd highest in cancer mortality rates
- Cancer rates for Incidence and Mortality by county (source 2007 Kentucky Cancer Registry)
- Kentucky is ranked 5th in the nation in deaths from coronary heart disease and overall cardiovascular disease
- Kentucky is ranked 6th as one of the nation’s worst location of allergies
- In most cases, serious health problems in Kentucky can be explained by its heavy smoking rate (one of the highest in the nation)
- Map of Adult Kentucky Illicit Drug Use Population
- Incidence of Mental stress, depression and emotional problems in the Adult Kentucky Population
