In 2002, Billings Clinic Research Center significantly expanded
both physical space and research efforts by moving into a new
22,000 square foot building located on the campus of Billings
Clinic.
Dr. Howard R. Knapp, M.D., Ph.D. is the Vice President of
Research. The overall goal of the Billings Clinic Research Center
is to bring the benefits of the newest medical research to patients
and their physicians in the Billings area, and to provide a medical
research focus here that is both clinical and laboratory-based.
Billings Clinic Research Center is involved in phase I, II, III,
and IV clinical trials in human participants.
A state-of-the-art laboratory is equipped and staffed to study
lipids, nutraceuticals and other health related topics.
Billings Clinic Research also expanded their outreach efforts by
equipping one 35-foot mobile vehicle with a DEXA scan and clinical
lab for nutrition research and a similar vehicle with a cardiology
lab that will travel throughout Montana and adjoining states. Our
latest outreach effort will find our "bus" traveling to
eight Native American reservations; seven in Montana and one in
Wyoming.
Billings Clinic Research Center is involved daily with DEXA
(bone density) scans, as a leading referral site by many area
physicians for their patients with osteoporosis or bone health
concerns. Billings Clinic Research is equipped with a unique
software program that, when combined with a DEXA scan, will enable
clinicians to evaluate a patient’s risk for fractures. This is
called an Instant Vertebral Assessment or IVA.
Patients with lipid disorders can receive highly specialized
lipid expertise here.
Every spring, students from 25 counties in southeast Montana and
northern Wyoming have an opportunity to compete in a sanctioned,
regional science fair through our Science Expo program.
Future areas of growth for the Research Center may include an
expansion of the building, faster diagnostic tests to complement
clinical studies that now must be sent to Mayo or other reference
labs, collaboration with businesses such as the Montana Department
of Commerce, area colleges and physicians, and provide lab space
for physicians interested in part-time clinical work.
All of these efforts are designed to improve the treatment of
disease in area patients which we have been doing since 1988.
Since 1988, the Deaconess Billings Clinic Research Center has
been involved in the following areas:
| Therapeutic
Areas: |
Sponsor: |
| Acute Coronary Syndrome |
Aventis, AstraZeneca, Lilly, Schering-Plough, Guilford
Pharmaceuticals |
| Allergic Rhinitis |
Aventis |
| Asthma |
Novartis; Aventis |
| Bipolar |
GlaxoSmithKline |
| Bone Metabolism |
Boehringer Mannheim, Hoechst Marion Roussel |
| Cholesterol Lowering |
Astra-Zeneca; Schering-Plough; Pfizer; Merck |
| Chronic Pain Syndrome |
Pfizer/Parke-Davis |
| Contraceptives and Bone Density |
Pharmacia-Upjohn |
| Crohn’s Disease |
Fuji/Mayo; Abbott; Berlex |
| Depression |
Lilly |
| Diabetes |
Roche; Bristol Myers Squibb; Takeda; Pfizer; Novartis,
MannKind, Daiichi |
| Diabetic Hyperlipidemia |
Bayer |
| Diabetic Peripheral Neuropathy |
GlaxoSmithKline; Wyeth, Pfizer |
| Diabetes Prevention |
Novartis; Pfizer |
| Endometriosis |
Pharmacia-Upjohn |
| Genital Herpes |
Novartis |
| Gout |
TAP |
| Hepatitis C |
Schering-Plough |
| High Blood Pressure |
Novartis |
| High Cholesterol |
Merck; Pfizer |
| Hormone Replacement Therapy |
Organon; Watson, Berlex, Rhone-Poulenc Rorer, Proctor &
Gamble, Wyeth-Ayerst, Lilly, Schering-Plough, ALZA,
Ciba-Geigy |
| Hyperlipidemia |
NIH, SmithKline Beecham, Schering-Plough, Bayer, Merck,
AstraZeneca, Pfizer, Bristol Myers Squibb |
| Hypertension |
Bristol Myers Squibb; Novartis, Reddy Laboratories,
NIH |
| Low Libido |
Proctor Gamble; BioSante |
| Multiple Sclerosis |
Genentech, Daiichi |
| Nutraceuticals |
Omega-3 Fatty Acids, Phytosterols, Dietary Fiber, Effects of
Different Dietary Fats |
| Oncology |
Amgen, Abbott, AstraZeneca, Cell Genesys, Aventis, Lilly,
Telik, Sanofi-Aventis |
| Osteoarthritis |
Searle, Novartis, GlaxoSmithKline |
| Osteoporosis |
Boehringer Mannheim, Rhone-Poulenc Rorer, Pfizer, Lilly, Sanofi
Winthrop, Proctor & Gamble, Roche, Wyeth-Ayerst, Pharmacia
& Upjohn, Ostex, Novartis |
| Osteoporosis Prevention |
Aventis; Wyeth-Ayerst |
| Osteoporosis Treatment |
Aventis; Wyeth-Ayerst; P & G; Roche |
| Painful Diabetic Neuropathy |
Wyeth |
| Pneumonia |
Pfizer, Searle, Merck, Amgen, Knoll, Roche |
| Rheumatoid Arthritis |
Knoll; Amgen |
| Septic Shock |
Apex; Lilly |
| Stroke |
ONO, Lorex, NTI |
| Ulcerative Colitis |
ISIS |
| Urinary Incontinence |
Roche |
| Uterine Fibroid |
TAP |
| Vaginal Atrophy |
Pfizer, Duramed |
Built in 2002, the Research building encompasses over 22,000
square feet located within the medical corridor at 1045 N. 30th
Street in Billings, Montana. Prior to this site, operations were
located on Poly Drive. Future plans include the addition of a third
floor for clinical research and a fourth floor for
laboratories.
Howard R. Knapp, M.D., Ph.D. began as Executive
Director of the Billings Clinic Research Center in March 2000 and
was promoted to Vice President Research in 2006. Prior to his
arrival, Dr. Knapp was appointed Professor in the Departments of
Internal Medicine and Pharmacology at the University of Iowa. He
obtained his M.D. from Vanderbilt University School of Medicine in
1977, and his Ph.D. in Pharmacology at Vanderbilt University in
1984.
Dr. Knapp was the Associate Director of the Clinical Research
Center and Director of the Lipid Clinic at the University of Iowa.
In 1996, he created the Bariatric Pharmacology Clinic for the drug
treatment of obesity. He was the Editor-in-Chief of the journal
Lipids from 1995 to 2006 and is on the editorial board of the
Journal of the American College of Nutrition. He was a member of
the Governing Board of the International Society for the Study of
Fatty Acids (1999-2003). Since moving to Billings, Dr. Knapp was
elected to a 5-year term on the Expert Committee for Cardiovascular
and Renal Drugs of the USP.
Dr. Knapp’s primary research interest is in clinical
pharmacology, which involves both developing new treatments for
human diseases and using drugs with known actions to get a better
understanding of disease processes. He has authored over 75
scientific articles and reviews. The overall goal of the Billings
Clinic Research Center is to bring the benefits of the newest
medical research to patients and their physicians in the Billings
area, and to provide a medical research focus in Billings that is
both clinical and laboratory-based. He hopes to establish a number
of collaborations with other doctors and researchers in the
Billings area to attract more funding opportunities and support an
array of new treatments for patients in our region.
The Billings Clinic Research Center is currently working with 35
nurses, doctors, dietitians, radiology technologists, respiratory
therapists and other staff carrying out different aspects of our
studies by NIH and major pharmaceutical companies.
The Research Center employs the following
personnel:
- One Research Manager
- One Administrative Assistant
- Five RN Study Coordinators
- One LPN for Clinical Trial Recruitment
- Two Radiology/DEXA Technologists with a combined 18 years
experience
- Two Full Time Medical Assistants
- One Satellite Project Chauffeur
- Two Clinical Data Specialists
- One Regulatory Specialist
- Two Research Chemists
- One Science Expo Specialist
- One Accountant
- Five Secretarial/Support Staff
Billings, Montana is a central location for a multi-state region
serving both rural and urban populations. The population is
primarily Caucasian, with 52% female and 48% male. The age ratio
is: 1 - 18 years (29%), 19 - 39 years (33%), 40 - 59 years (22%),
60+ years (16%).