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Research Center Profile:
Oklahoma Foundation for Digestive Research

Center Information

Oklahoma Foundation for Digestive Research
1000 N. Lincoln Blvd.
Suite 210
Oklahoma City, OK 73104
USA
405-271-4602
405-271-3116 (fax)
digestiveresearch@ouhsc.edu
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Therapeutic Areas

Gastroenterology
Healthy Volunteers

Center Overview

OFDR is a private, non-profit medical research foundation. Our mission is to advance basic science and clinical research in gastrointestinal disease, treat patients with such diseases, participate in the training of physicians, and to educate the public about gastrointestinal illnesses. Our free-standing clinical research center is affiliated with the private gastroenterology practice of Dr. Philip B. Miner, Jr., M.D., board-certified gastroenterologist. Dr. Miner joined OFDR in 1996 as President and Medical Director. He is also Clinical Professor of Medicine at the University of Oklahoma. Before joining OFDR, he was Professor of Medicine and Director of the Division of Gastroenterology at the University of Kansas for 19 years. His contributions to the scientific literature include more than 200 articles, book chapters and abstracts. He lectures widely on topics related to gastroenterology and is recognized nationally and internationally for his expertise in Inflammatory Bowel Disease, motility disorders, anorectal manometry and mast cells. He has served on advisory boards to several major pharmaceutical companies.

OFDR encompasses both clinical research and a basic sciences laboratory. Our staff of 22 includes 4 full-time clinical research coordinators, 2 GI laboratory technicians, and 1 Physician's Assistant in addition to our basic sciences personnel and administrative staff.

OFDR offers many unique and valuable aspects to sponsors and patients alike. Because we focus ONLY on research in gastroenterology, the level of knowledge, experience and expertise our staff and physicians are able to provide in these diseases is unmatched.

Clinical Research Experience

To date, OFDR has conducted over 275 clinical trials in gastroenterology including Phase I-IV, Rx-OTC switch, and post-marketing studies. Within the sub-specialty of gastroenterology, our interests include:

  • Inflammatory Bowel Disease
    • Crohn's disease
    • Ulcerative Colitis
  • Motility disorders
    • Irritable Bowel Syndrome
    • Constipation
    • Non-Ulcer Dyspepsia
    • Gastroparesis
  • Gastroesophageal Reflux Disease
    • Erosive and Non-Erosive Esophagitis
    • Provocative meals for heartburn sufferers
    • Gastroesophageal Mucosal Damage
    • NSAID damage

Facility Description

Located in the heart of Oklahoma City's medical community on the campus of the University of Oklahoma Health Sciences Center, OFDR is approximately 15 minutes from Will Rogers Airport and centrally positioned near major freeways (I-35 and I-40 "crossroads of the U.S."). Our clinical research offices are physically located in the Presbyterian Professional Office Building, adjacent to Presbyterian Hospital, a 400-bed tertiary care facility. We have access to hospital services including outpatient surgery for endoscopic procedures requiring sedation, laboratory, -70 freezer, radiology, pathology, nuclear medicine, and in-patient housing. We routinely utilize central IRB and central laboratory services.

We provide gastrointestinal motility laboratory services for Presbyterian Hospital and the community. Our gastrointestinal motility laboratory capabilities are regionally unmatched. Tests we perform include pH monitoring, anorectal and esophageal manometry, Bernstein testing, and hydrogen breath testing for bacterial overgrowth and transit studies. Our equipment includes both solid state and water perfusion Synectics motility systems, 14 Synectics/Medtronics digitrappers for ambulatory pH monitoring, and a barostat for studies of visceral hyperalgesia. Additional equipment includes a centrifuge, 2 ECG machines and a 'robot' for vitals.

Our physical location includes:

  • private offices
  • study monitor office which accommodates 3 monitors simultaneously with locking record storage, individual workspaces, and private telephones
  • conference room with audio-visual capabilities
  • reception area
  • accounting office
  • GI Motility Laboratory
  • locked drug storage
  • phlebotomy laboratory and supply storage
  • locked refrigerator
  • -20 freezer and dry ice storage

Adjacent private practice includes:

  • reception area
  • 4 exam rooms
  • endoscopic procedure room
  • nursing station
  • private offices

We have utilized pc-based remote data entry, fax/scan monitoring, electronic patient diaries and interactive voice response systems. We have a local-area network consisting of 20 pc's with database access, internet access, e-mail communications, and a full-time network administrator.

Staff Expertise

We have a professional, experienced and well-trained research staff who are committed to exceeding client expectations for patient enrollment and data integrity while providing thorough, complete and compassionate health care to our patients.

Patient Demographics

The Oklahoma City metropolitan area covers 6 counties and has a population of 1 million. The area is host to 16 colleges and universities.

We recruit study participants from our existing database, private practice and through advertising mediums including radio, tv, newspaper, newsletters, flyers, and disease support groups.

Other Information

OFDR can assist in many aspects of a research program offering services including:

  • program development and strategic planning
  • protocol design & development
  • statistical analysis of results & final study reports
  • medical writing and publication
  • presentation of data at scientific meetings

Patients: If you are interested in enrolling in one of the clinical trials conducted by this center, or to receive additional information, fill out the form below to send an e-mail message to the center.

or visit our enterWatch listing (below) to see if you qualify for one of our studies.

For further information on the Foundation or placement of clinical trials, please contact OFDR at 405-271-4602 or digestiveresearch@ouhsc.edu.

Contact Center

If you are interested in contacting this center to discuss placing a clinical trial there, please complete and send the email form below. A representative from the research center will then follow up with you.

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