Research Center Profile:
Oklahoma Foundation for Digestive Research

OFDR is a private, non-profit medical research foundation. Our
mission is to advance basic science and clinical research in
gastrointestinal disease, treat patients with such diseases,
participate in the training of physicians, and to educate the
public about gastrointestinal illnesses. Our free-standing clinical
research center is affiliated with the private gastroenterology
practice of Dr. Philip B. Miner, Jr., M.D., board-certified
gastroenterologist. Dr. Miner joined OFDR in 1996 as President and
Medical Director. He is also Clinical Professor of Medicine at the
University of Oklahoma. Before joining OFDR, he was Professor of
Medicine and Director of the Division of Gastroenterology at the
University of Kansas for 19 years. His contributions to the
scientific literature include more than 200 articles, book chapters
and abstracts. He lectures widely on topics related to
gastroenterology and is recognized nationally and internationally
for his expertise in Inflammatory Bowel Disease, motility
disorders, anorectal manometry and mast cells. He has served on
advisory boards to several major pharmaceutical companies.
OFDR encompasses both clinical research and a basic sciences
laboratory. Our staff of 22 includes 4 full-time clinical research
coordinators, 2 GI laboratory technicians, and 1 Physician's
Assistant in addition to our basic sciences personnel and
administrative staff.
OFDR offers many unique and valuable aspects to sponsors and
patients alike. Because we focus ONLY on research in
gastroenterology, the level of knowledge, experience and expertise
our staff and physicians are able to provide in these diseases is
unmatched.
To date, OFDR has conducted over 275 clinical trials in
gastroenterology including Phase I-IV, Rx-OTC switch, and
post-marketing studies. Within the sub-specialty of
gastroenterology, our interests include:
- Inflammatory Bowel Disease
- Crohn's disease
- Ulcerative Colitis
- Motility disorders
- Irritable Bowel Syndrome
- Constipation
- Non-Ulcer Dyspepsia
- Gastroparesis
- Gastroesophageal Reflux Disease
- Erosive and Non-Erosive Esophagitis
- Provocative meals for heartburn sufferers
- Gastroesophageal Mucosal Damage
- NSAID damage
Located in the heart of Oklahoma City's medical community on
the campus of the University of Oklahoma Health Sciences Center,
OFDR is approximately 15 minutes from Will Rogers Airport and
centrally positioned near major freeways (I-35 and I-40
"crossroads of the U.S."). Our clinical research offices
are physically located in the Presbyterian Professional Office
Building, adjacent to Presbyterian Hospital, a 400-bed tertiary
care facility. We have access to hospital services including
outpatient surgery for endoscopic procedures requiring sedation,
laboratory, -70 freezer, radiology, pathology, nuclear medicine,
and in-patient housing. We routinely utilize central IRB and
central laboratory services.
We provide gastrointestinal motility laboratory services for
Presbyterian Hospital and the community. Our gastrointestinal
motility laboratory capabilities are regionally unmatched. Tests we
perform include pH monitoring, anorectal and esophageal manometry,
Bernstein testing, and hydrogen breath testing for bacterial
overgrowth and transit studies. Our equipment includes both solid
state and water perfusion Synectics motility systems, 14
Synectics/Medtronics digitrappers for ambulatory pH monitoring, and
a barostat for studies of visceral hyperalgesia. Additional
equipment includes a centrifuge, 2 ECG machines and a
'robot' for vitals.
Our physical location includes:
- private offices
- study monitor office which accommodates 3 monitors
simultaneously with locking record storage, individual workspaces,
and private telephones
- conference room with audio-visual capabilities
- reception area
- accounting office
- GI Motility Laboratory
- locked drug storage
- phlebotomy laboratory and supply storage
- locked refrigerator
- -20 freezer and dry ice storage
Adjacent private practice includes:
- reception area
- 4 exam rooms
- endoscopic procedure room
- nursing station
- private offices
We have utilized pc-based remote data entry, fax/scan
monitoring, electronic patient diaries and interactive voice
response systems. We have a local-area network consisting of 20
pc's with database access, internet access, e-mail
communications, and a full-time network administrator.
We have a professional, experienced and well-trained research
staff who are committed to exceeding client expectations for
patient enrollment and data integrity while providing thorough,
complete and compassionate health care to our patients.
The Oklahoma City metropolitan area covers 6 counties and has a
population of 1 million. The area is host to 16 colleges and
universities.
We recruit study participants from our existing database,
private practice and through advertising mediums including radio,
tv, newspaper, newsletters, flyers, and disease support groups.
OFDR can assist in many aspects of a research program offering
services including:
- program development and strategic planning
- protocol design & development
- statistical analysis of results & final study reports
- medical writing and publication
- presentation of data at scientific meetings
Patients: If you are interested in enrolling in
one of the clinical trials conducted by this center, or to receive
additional information, fill out the form below to send an e-mail
message to the center.
or visit our
enterWatch
listing (below) to see if you qualify for one of our studies.
For further information on the Foundation or placement of clinical trials, please contact OFDR at 405-271-4602 or
digestiveresearch@ouhsc.edu.
Oklahoma Foundation for Digestive Research
1000 N. Lincoln Blvd.
Suite 210
Oklahoma City, OK 73104
USA
Phone: 405-271-4602
Fax: 405-271-3116
EMail: digestiveresearch@ouhsc.edu
If you are interested in contacting this center to discuss placing a clinical
trial there, please complete and send the E-mail form below. A representative from
the research center will then follow up with you.