Research Center Profile:
The Margolin Brain Institute
Neurology
Psychiatry/Psychology
Dr. David Margolin, the principal investigator, is a Board
Certified Neurologist with over 30 years experience in treating
patients with Alzheimer’s disease, Parkinson’s disease, and other
neurological illnesses. He has conducted over 150 clinical trials
in Neurology and Psychiatry. All studies are conducted at the
Margolin Brain Institute, a state-of-the-art facility which houses
Dr. Margolin’s private neurology practice and the clinical trials
research.
We have been involved in clinical research for 20 years.
We focus on research phases: II through IV
Our therapeutic specialties include:
All neurological and psychiatric disorders, with special expertise
in Alzheimer's disease and Parkinson's disease.
The sponsors we have worked with include:
- Abbott Laboratories
- Acadia Pharmaceuticals
- Amgen, Inc.
- Bayer Corporation
- Biovail Corporation
- Boehringer Ingelheim Pharmaceuticals
- Bristol-Myers Squibb
- Dainippon Sumitomo
- David Pharmaceuticals
- DuPont Merck Pharmaceutical Co.
- Eisai America, Inc.
- Eli Lilly and Company
- EPIX Pharmaceuticals
- Forest Laboratories
- Fujisawa Research of America, Inc.
- G.D. Searle
- Glaxo Inc.
- GlaxoSmithKline
- H. Lundbeck
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- Hoechst-Roussel Pharmaceuticals
- Hoffman LaRoche
- Janssen Research Foundation
- John & Johnson
- Kyowa Pharmaceuticals
- Medivation
- Memory Pharmaceuticals
- Merck Research Laboratories
- Merz + Co. GmbH & Co.
- Miles Inc.
- Mitsubishi Pharmaceuticals
- Mylan Pharmaceuticals
- NeoTherapeutics, Inc.
- Novartis Pharmaceuticals
- Neurochem Inc.
- Ono Pharma USA
- Ovation Pharmaceutical Development
- Parke-Davis Pharmaceutical Research
- Pentech Pharmaceuticals
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- Pfizer, Inc.
- Pharmacia and UpJohn, Inc.
- Protodigm, Ltd.
- Saegis Pharmaceuticals
- Sandoz Pharmaceutical Corporation
- Sanofi-Synthelabo Research
- Schwab GmbH & Co.
- Schwarz Biosciences
- Sention Inc.
- Smith-Kline Beecham Corporation
- Somerset Pharmaceuticals
- Takeda America
- Teikoku Pharma USA
- TEVA Pharmaceuticals
- Toyama USA, Inc.
- TransTech Pharma
- United BioSource Corporation
- Voyager Pharmaceuticals
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The CROs we have worked with include:
- Barton & Polansky
- Covance
- CroMedica
- IBIRD
- ICON Clinical Trials
- Ingenix Pharmaceutical Services
- Kendle
- Lineeberry
- Medex Clinical Trials Service
- Omnicare
- Paragon
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- Parexel International
- Parkinson’s Study Group
- PPD
- PRA International
- Premiere Research Inc.
- Protrials, Inc.
- Quintiles Pacific, Inc.
- SciRex
- SRA International
- The Hardardt Group
- Worldwide Clinical Trials
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The Margolin Brain Institute, which opened in April, 2000,
occupies 5,000 square ft. in a custom-designed, single story,
state-of-the-art office building in Northeast Fresno. The staff
utilizes a comprehensive, computerized, clinical trial data
management system, which simultaneously records and organizes
patient demographics, schedules patients according to individual
study protocols, and tracks patient visits and procedures. The
system runs on a Windows 2000 LAN network, which also supports all
Microsoft Office 2000 programs.
David Ira Margolin, M.D., Ph.D., J.D.
Areas of Expertise:
Neurology - Alzheimer's, Parkinson's, Mild cognitive
impairment, Headache, Vascular Dementia, Stroke, Pain
Psychiatry - Depression
J.J. Margolin, R.N., F.N.P., C.C.R.C.
Clinical Trials Supervisor
20 years experience in clinical research
In addition to J.J. Margolin, who has collaborated with Dr.
Margolin on over 100 clinical trials during the past 20 years,
there are usually 4 clinical coordinators on staff.
This site is the main neuroscience clinical trials center in
Central California. This nine-county region has a population of
about 3 million. Fresno County alone, with about 1,000,000 residents,
is more populous than San Francisco County. The Central
Valley's population of people 55 and older (280,000 in 2000) is
growing rapidly.
This site operates independent of any larger bureaucracy thus
eliminating the administrative delays frequently encountered at
institution-related sites. Contracts can be executed within 24
hours and the site is free to use the IRB of the sponsor's
choice. Several study coordinators have used remote data entry
systems in clinical trials. Many staff members have expertise in
neuropsychological measures currently in use in Alzheimer's
clinical trials including the CIBIC, CDR, ADAS, and NPI.
If you are interested in contacting this center to discuss placing a clinical
trial there, please complete and send the e-mail form below. A representative from
the research center will then follow up with you.
