Therapeutic Areas

Neurology
Psychiatry/Psychology

Center Overview

Dr. David Margolin, the principal investigator, is a Board Certified Neurologist with over 30 years experience in treating patients with Alzheimer’s disease, Parkinson’s disease, and other neurological illnesses. He has conducted over 150 clinical trials in Neurology and Psychiatry. All studies are conducted at the Margolin Brain Institute, a state-of-the-art facility which houses Dr. Margolin’s private neurology practice and the clinical trials research.

Clinical Research Experience

We have been involved in clinical research for 20 years.

We focus on research phases: II through IV

Our therapeutic specialties include:
All neurological and psychiatric disorders, with special expertise in Alzheimer's disease and Parkinson's disease.

The sponsors we have worked with include:

The CROs we have worked with include:

Facility Description

The Margolin Brain Institute, which opened in April, 2000, occupies 5,000 square ft. in a custom-designed, single story, state-of-the-art office building in Northeast Fresno. The staff utilizes a comprehensive, computerized, clinical trial data management system, which simultaneously records and organizes patient demographics, schedules patients according to individual study protocols, and tracks patient visits and procedures. The system runs on a Windows 2000 LAN network, which also supports all Microsoft Office 2000 programs.

Investigator Experience

David Ira Margolin, M.D., Ph.D., J.D.

Areas of Expertise:
Neurology - Alzheimer's, Parkinson's, Mild cognitive impairment, Headache, Vascular Dementia, Stroke, Pain
Psychiatry - Depression

Staff Expertise

J.J. Margolin, R.N., F.N.P., C.C.R.C.
Clinical Trials Supervisor
20 years experience in clinical research

In addition to J.J. Margolin, who has collaborated with Dr. Margolin on over 100 clinical trials during the past 20 years, there are usually 4 clinical coordinators on staff.

Patient Demographics

This site is the main neuroscience clinical trials center in Central California. This nine-county region has a population of about 3 million. Fresno County alone, with about 1,000,000 residents, is more populous than San Francisco County. The Central Valley's population of people 55 and older (280,000 in 2000) is growing rapidly.

Other Information

This site operates independent of any larger bureaucracy thus eliminating the administrative delays frequently encountered at institution-related sites. Contracts can be executed within 24 hours and the site is free to use the IRB of the sponsor's choice. Several study coordinators have used remote data entry systems in clinical trials. Many staff members have expertise in neuropsychological measures currently in use in Alzheimer's clinical trials including the CIBIC, CDR, ADAS, and NPI.

Contact Center

If you are interested in contacting this center to discuss placing a clinical trial there, please complete and send the e-mail form below. A representative from the research center will then follow up with you.