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Research Center Profile:
Bone & Joint Hospital Research Dept


Contact Info

Helen Kelley, RN, Ph.D., CCRP
Director, Research Department
Bone & Joint Hospital Research Dept
1111 N. Dewey Avenue
Oklahoma City, OK 73103
USA
Phone: 405-552-9492, 405-552-9525, 405-552-9521, 405-552-9521
Fax: 405-552-9110
EMail: Helen_Kelley@ssmhc.com
Web Site: http://www.boneandjoint.com/internet/home/boneandjoint.nsf/documents/Clinical+Research
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Contents

Center Overview
Clinical Research Experience
Facility Description
Investigator Experience
Patient Demographics
Other Information
Contact Information
Enrolling Trials

Therapeutic Areas:

Musculoskeletal
Rheumatology

Center Overview

Bone & Joint Hospital is a licensed 102 -- bed, orthopedic specialty hospital providing surgical, medical and comprehensive medical rehabilitative care. The medical staff includes specialists in orthopedic surgery, pediatric orthopedic surgery, anesthesiology/pain management, musculoskeletal radiology, spine surgery, sports medicine and orthopedic trauma.

Currently, a variety of studies are being conducted which involve either joint implant devices or pharmaceuticals. We strive to offer our patients the best of new technology as well as attention to their individual needs.

Bone & Joint Hospital is accredited by The Joint Commission and is a member of the American and Oklahoma Hospital Associations.

Clinical Research Experience

Several physicians have participated in component and pharmaceutical trials in past years. In the late 1996, Helen Kelley, RN, Ph.D., CCRP was hired to focus on developing research capabilities and to recruit studies of potential benefit to our patient population. We have completed studies in Phases I, II, III, and IV. Our Research Department staff includes 4 full time study coordinators: Daniel Dodson, Ph.D., ATC; Reda Mewhorter, MLT (ASCP), CCRP; Lori Patton, MT (ASCP) CCRP; and Delana Rodgers, LPN.

Facility Description

Bone & Joint Hospital or its affiliates has other capabilities which include radiology, laboratory, MRI, and DEXA bone density equipment. We are located across the street from St. Anthony Hospital, which has additional full service availability of CT, bone scanning, ultrasound, and venography. Many of our physicians serve as clinical faculty at the nearby University of Oklahoma Health Sciences Center, or in the Osteopathic Medicine Department of Oklahoma State University.

Our physicians have a variety of interests. The interests of our orthopedists include upper and lower extremity joint replacement (primary and revision), sports medicine, spine surgery, and arthroscopy. In Rheumatology, our physicians have particular interest in osteoarthritis, rheumatoid arthritis, chronic pain, systemic lupus, and osteoporosis. We have worked with a number of companies, including Sulzer (Centerpulse) Orthopedics, Encore Orthopedics, SmithKline Beecham, Ortho Biotech, Searle, Merck, Bristol Myers Squibb, Centocor, Aventis, Amgen, Novartis, XOMA, Abbott, Eli Lilly, Genentech, Human Genome Sciences, Alza, Valex Pharmaceuticals, Targeted Genetics Corporation, Hoffman- LaRoche, CombinatoRx, and UCB.

Investigator Experience

R. Eugene Arthur, MD
Internal Medicine/Rheumatology. Principal Investigator:Studies of biologic intravenous pharmaceuticals for RA and SLE. Studies of NSAID pharmaceuticals in OA patients; Studies of anti – TNF pharmaceuticals in RA; Pharmaceutical treatment of hypertension.
Subinvestigator: Study of NSAID pharmaceuticals in RA patients; Study of TNF inhibitor for RA; Study of NSAID pharmaceuticals in OA patients; compliance study of osteoporosis patients.

Robert F. Hynd, MD
Internal Medicine/Rheumatology. Principal Investigator: Studies of NSAID pharmaceuticals in OA patients; Studies of TNF inhibitor pharmaceuticals in RA patients. Studies of NSAID pharmaceuticals in RA patients.
Subinvestigator: Compliance study of osteoporosis patients; NSAID treatment of OA. Studies of biologic pharmaceuticals.

Robert L. McArthur, MD
Internal Medicine/Rheumatology. Principal Investigator: Studies of IV biologics in SLE and RA, Studies of NSAID treatment of OA.
Subinvestigator: TNF pharmaceutical in RA; pharmaceutical treatment of osteoporosis; Compliance study of osteoporosis patients; NSAID treatment of OA. Studies of biologic pharmaceuticals for RA and SLE.

Thomas Janssen, MD
Orthopedic Surgery. Principal Investigator:Investigational narcotic study for OA pain.
Subinvestigator: NSAID treatment of OA.

Brock E. Schnebel, MD
Orthopedic Surgery. Principal Investigator: Pharmaceutical study of blood replacement after elective back surgery; study of bone density in collegiate gymnasts.

Amy Shultz, MD
Internal Medicine/Rheumatology. Subinvestigator: Studies of IV biologics in SLE.

Thomas K. Tkach, MD
Orthopedic Surgery. Principal Investigator: Component study of tibial insert design in total knee arthroplasty; follow-up study of total hip revision patients; studies of NSAID pharmaceutical use immediately after total knee arthroplasty with Apex hip stem.

Larry G. Willis, MD
Internal Medicine/Rheumatology. Principal Investigator: Studies of IV biologics in SLE and RA. Compliance/long term side effects study of osteoporosis patients; pharmaceutical study of steroid - induced osteoporosis; pharmaceutical study of oral osteoporosis drug.
Subinvestigator: Studies of IV biologics in SLE and RA. Study of NSAID pharmaceuticals in OA patients; study of TNF pharmaceuticals in RA; study of NSAID pharmaceuticals in RA; pharmaceutical study of hypertension.

J. Calvin Johnson, M.D.
Principal Investigator: Therapeutic use of topical hyaluronic acid for joint inflammatory conditions in the knee. Sports medicine, knee and shoulder surgery fellowship. Specializing in sports medicine, sports injuries, shoulder and knee arthroscopic surgery.

Robert F. Hines, M.D.
Principal Investigator: Overtraining in athletes. Specializing in sports medicine, sports injuries, shoulder and knee arthroscopic surgery.

Jimmy H. Conway, M.D.
Specializing in shoulder, knee, sports medicine, complex sports injuries and shoulder arthroscopic surgery.

Steven D. Coupens, M.D.
Sports medicine fellowship. Specializing in general orthopedics, joint reconstruction, shoulder, knee, sports medicine and foot/ankle.

William H. Herndon, M.D.
Pediatric orthopedics and spinal deformities fellowship. Specializing in adolescent and pediatric orthopedics, sports medicine and spine.

Helen Kelley, RN, Ph.D., CCRP
Doctorate in Epidemiology/Biostatistics Twenty years experience designing, implementing, and analyzing studies in general surgery, orthopedics, and internal medicine/rheumatology; SoCRA certification 2007. Nine years nursing experience in medical/surgical care of adults. Serves as subinvestigator on all Research Department studies. Areas of particular interest include biologic treatments of inflammatory arthritis, total knee arthroplasty, medical writing, survey research, and incidence of venous thromboembolism after orthopedic surgery.

Daniel L. Dodson, Ph.D., A.T.,C.
Doctorate in Health, Leisure, and Human Performance/Certified Athletic Trainer Five years designing, implementing, and analyzing studies in athletics and orthopedics; 18 years experience as NATA certified athletic trainer. Areas of particular interest include overtraining syndrome especially in rehabilitation, hyaluronic acid in joint pain associated with OA.

Reda Mewhorter, MLT (ACSP), CCRP
American Society of Clinical Pathologists/Certified Medical Laboratory Technician Seven years experience coordinating clinical trials; SoCRA certification 2007. Twenty-five plus years experience in medical laboratories, including the oversight of the quality control laboratory for a large blood institute as well as the coordination of both industry and government sponsored research programs.

Lori A. Patton, MT, (ASCP), CCRP
American Society of Clinical Pathologists/Registered Medical Technologist. Eight years experience coordinating clinical trials; SoCRA certification 2007. Seventeen-plus years experience in a variety of clinical laboratory areas including laboratory information systems, quality control and routine blood testing.

Delana Rodgers, LPN
Licensed Practical NurseClinical trials study coordinator since Fall 2007. Three and one half years working at Bone & Joint Hospital, working in Rehabilitation unit as Certified Nursing Assistant and Emergency Room as unit secretary.

Patient Demographics

The Oklahoma City metropolitan area is home to over one million people; in addition, our clinic patients originate from parts of Kansas, Texas, and Arkansas. We have a large population of elderly patients, but also draw a number of younger patients with chronic joint problems, connective tissue disease, trauma, and sports injuries. Additionally, we treat a moderate number of patients who are Native American and a small number of African Americans and Asians.

Contact Information

Helen Kelley, RN, Ph.D., CCRP
Director, Research Department
Bone & Joint Hospital Research Dept
1111 N. Dewey Avenue
Oklahoma City, OK 73103
USA
Phone: 405-552-9492, 405-552-9525, 405-552-9521, 405-552-9521
Fax: 405-552-9110
EMail: Helen_Kelley@ssmhc.com
Web Site: http://www.boneandjoint.com/internet/home/boneandjoint.nsf/documents/Clinical+Research



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