Wake Research Associates, established in 1984, is a nationally recognized professional research organization specializing in conducting pharmaceuticals, device and nutrition trials. Wake Research Associates is an independent research center based on an 18 physicians’ multi-specialty private practice drawing from a current patient population of approximately 80,000. We are affiliated with two major hospitals within close proximity: Wake Medical and Rex Hospital. WRA is also affiliated with 27 subspecialty physicians in the Raleigh area. WRA’s association with Key IPA and its 140 physicians allows a greater outreach to our community. Our on site sleep lab, Wake Sleep Center has 12 patient beds and certified polysomnographic technicians.
We have over 20 years of clinical research experience. As of 2007, our board certified physicians have completed more than 2050 successful clinical trials. Clinical trials at our site are always completed on time and with accuracy; we consistently exceed sponsor expectation for integrity, subject enrollment, human protection and expeditious delivery of accurate evaluable data.
Wake Research Associates is a unique and innovative resource for Phase I-IV clinical trials. Our site is known for effectively combining strategic patient recruitment and retention with high quality clinical research procedures. Our approach is uncompromising - each study conducted at our site is carefully planned and executed according to regulations with superior quality.
Our focus is on Phase I-IV research trials and pharmokinetics
studies. As of 2007, Wake Research has successfully conducted more
than 2,050 clinical trials.
We conduct our clinical trials to ensure timely completion as
well as high-quality and accurate work. We continually exceed
sponsor expectations of integrity, subject enrollment goals, and
human protection in addition to expeditious delivery of accurate
evaluable data. Wake Research consistency monitors its team and
work performance seeking room for improvement and growth. Our goals
include team collaboration to improve the care of our patients and
aid in the rapid availability of new, cutting-edge treatments to
our patients and the community.
Our therapeutic specialties include:
- Internal Medicine
- Gastroenterology
- Pulmonology/Immunology
- Cardiology
- Infectious Diseases
- Gynecology/Women's Health
- Rheumatology
- Urology
- Psychiatry
- Neurology
- Provocative Meal Studies
- Pain Management
- Medical Devices
- Rx to OTC Studies
- Dermatology
- Weight Management/Nutrition
We have conducted/are currently conducting studies for
the following conditions:
- Gastrointestinal Diseases
- Irritable Bowel Syndrome
- Gastro-esophageal Reflux Disease
- Erosive Esophagitis
- Heartburn
- Colorectal CA Screen
- Crohn's Disease
- Ulcerative Colitis
- Functional Dyspepsia
- Constipation
- Gastroparesis
- Provocative Meal Studies
- Anal Fissures
- Fatty Liver Disease or NASH
- Diverticulitis
- General Medicine
- Chronic Bronchitis
- Osteoarthritis of Knee/Hip
- Insomnia
- Smoking Cessation
- Sinusitis
- ChronicBack Pain
- Chronic Pain Management
- Gout
- Diabetes
- Diabetes 2
- Asthma
- COPD
- Obesity
- Overactive Bladder
- Migraine
- Hypertension
- Hypercholesterolemia
- Fibromyalgia
- Healthy Volunteers
- Lower Back Spasms
- Weight loss
- Shingles Vaccine
- Flu Vaccine
- Restless Leg Syndrome
- Stuttering
- Athlete’s Foot
- Narcolepsy
- Nonrestorative Sleep
- Sciatica
- Sleep Apnea
- Traveler’s Diarrhea
- Tinnitus (ringing in ears)
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- Premenstrual Syndrome
- Vaginal Atrophy
- Sexual Dysfunction (women)
- Premenstrual Dysphoric Disorder
- Contraception
- Hormone Replaement Therapy
- Uterine Fibroids
- Osteoporosis
- Urinary Tract Infection
- Breast Pain
- Genital Warts
- Hot Flash
- Endometriosis
- Heavy Uterine Bleeding
- Low Sexual Desire
- Premature Ejaculation
- Prostate Cancer prevention
- Rapid Ejaculation
- Generalized Anxiety Disorder
- Panic disorder
- Acne
- Psoriasis
- Hyperhydrosis
- Rosacea
- Actinic Keratosis
- Oily Scalp
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We have worked with the following
sponsors:
Glaxo-Wellcome, Bristol Myers, Genetics Institute, G.D. Searle Pharmaceutical, Otsuka Pharmaceutical, Tap Pharmaceutical, Kabi Pharmaceutical, RW Johnson, BioCryst, Merck, Janssen Pharmaceutical, Wyeth Pharmaceuticals, Ciba Geigy, Eli Lilly, Upjohn, Schering Plough, Hoffman-LaRoche, Gilead, Bayer, Boehringer Ingelheim, KOS Pharmaceuticals, Parke-Davis Pharmaceuticals, Smith-Kline Beecham, Takeda America, Abbott Pharmaceutical, Pfizer, Novartis, Targacept, ALZA, Purdue Pharma, McNeil, Allergan, Pain Therapeutics, Sanofi-Synthelabo, Axcan, AstraZeneca, Centocor, Neurocrine Biosciences, Pharmacia, Berlex, Barr Research, Inspire, Santarus, Elan, Celgene, Celltech, Acambis, Braintree, Baxter, Novum, Arena Pharmaceuticals, Hisamitsu, BioSante, Apotex, Galderma, Strakan, Luitpold, Repros, Regeneron, Horizon Therapeutics, MedPointe, Orexigen, NiCox, Dow Pharmaceuticals, DuraMed Research, Cypress Bioscience, Nastech, Salix, Basilea Pharmaceutica, Pozen, Plethora, Amylin, Hutchinson, Vivus, Xenoport, Zars, Symbollon, Jazz, Shionogi, Glenmark, Organon, Schwarz, and Astellas.
CRO's:
ClinTrials, Quintiles, PPD-Pharmaco, Kendle, Kern McNeil, Premier Research, Scirex, IBRD, IBAH, Phoenix, Inc., InSite Clinical Trials, Bio Pharmaceutical, Parexel, Paragon, ICON, PRA, Dertech, TKL, AAI, Medpace, Kendall, Iveresk, Parexel, Integrium, Criterium, Essential, CompleWare, Omnicare, Metropolitian Research Associates, MedSource, Encorium, Premier, United Biosource, Covance, Pharm-Olam, Advanced Biologics, CTMS, Charles River, PharmaLink, Pharmanet and i3 Research.
IVRS & EDC Systems:
Oracle, Data Track, IcoPhone, Study Works, RAVE, eClinical, Medidata, Inform, Remote Data Capture, Impala IVRS, Phoenix Data Sytems, eTrials, ClinPhone, Covance, RAMOS, SBIR, Maaguzi, Omnicomm Trialmaster, Clarix and Phase Forward.
Wake Research Associates is focused on the needs of both patient
welfare and the growth of pharmaceutical research and
development.
Our site facilities include:
- Secured Investigational Drug Storage
- Certified Endoscopy Unit with 5 suites and recovery
- Certified Diagnostic Laboratory
- X-Ray Department with Bone Densitometer and Ultrasound Unit (3)
and
- Certified Mammography Unit
- Nuclear Medicine, heart station, EKG, treadmills, Holter
Monitor, echo ECG
- Complete Pulmonary Unit with Spirometry, Peak Flow Monitoring
& Survey System Plus
- Phase I and Pharmocokinetic Unit with infusion capabilities,
private rooms, shower and TV
- Facilities for Provocative Meal Studies
Wake Research Associates is conveniently located 15 minutes from
an international airport, minutes from major hotels, restaurants
and shops as well as one of Raleigh's largest hospitals, Rex
Hospital which is located just 0.5 miles from our site.
Our primary investigators are:
Charles Barish, MD
Area of expertise: Gastroenterology
Jonathan Flescher, MD
Area of expertise: Pulmonology , Sleep Medicine, and Smoking Cessation
Wayne Harper, MD
Area of expertise: Internal Medicine, Metabolic Disease and Vaccines Trials
Susan Eder, MD
Area of expertise: Psychiatry
Adnan Nasir, MD, PhD
Area of expertise: Dermatology
Pouru Bhiwandi, MD
Area of expertise: Gynecology and Women's Health
Singar Jagadeesan, MD
Area of expertise: Neurology and Sleep Medicine
Arvind N. Jariwala, MD
Area of expertise: Geriatrics and Internal Medicine
Stephen R. Coleman, MD
Area of expertise: Pediatrics
Our sub-investigators are:
Daniel Mollin, MD
Area of expertise: Internal Medicine
Bulent Ender, MD
Area of expertise: Gastroenterology
Treva Tyson, MD
Area of expertise: Women's Health and Internal Medicine
Ella Grach, MD
Area of expertise: Pharmacoviligance
Curtis Carlson, MD
Area of expertise: Internal Medicine
Seth A. Kaplan, MD
Area of expertise: Gastroenterology
Miroslav Gavazov, MD
Area of expertise: Internal Medicine
Jerome B. Gardner, MD
Area of expertise: Women’s Health
Marc A. Herschelman, DO
Area of expertise: Gastroenterology
MaryAnn Pollock, PhD
Area of expertise: Nutrition
Debrah Barish, MS
Area of expertise: Nutrition
David Colvard, MD
Area of expertise: Psychiatry
Research employees of Wake Research Associates include a variety
of health professionals such as registered nurses, LPN, CMA and
registered dieticians, all who assist investigators in conducting
all phases of clinical trials. Our clinical staff members are
certified in blood pressure monitoring, CPR, advanced cardiac life
support, ECG, phlebotomy and bone density scans.
Wake Research Associates has 12 full-time coordinators,
including 4 RN, 1 LPN, 1 CMA and 1 MA, Quality Assurance,
Regulatory Specialist, and 3 dedicated patient recruiters. Four
coordinators are certified by ACPR.
