Center Overview

Vista Clinical Research is a dedicated multispecialty research center. We participate in Phase II, III, IV, OTC, device and post marketing clinical trials. Vista Clinical Research is distinguished by:

• Investigators and staff with a 10-year history of conducting phase II-IV, OTC, device and post marketing clinical trials
• Experienced, certified coordinating staff
• Timely and successful enrollment of study subjects
• Delivery of high quality data with low query rates
• Orthopedic practice within its facility.

Clinical Research Experience

Clinical Research Experience:
We bring 10 years of experience in conducting clinical trials.

We conduct research in the following areas:

• Arthritis/Rheumatology (including Osteoarthritis, rheumatoid arthritis, fibromyalgia)
• Cardiovascular Disease (including peripheral vascular disease)
• Dermatology;Gastroenterology
• Musculoskeletal (including osteoporosis, arthritis, osteoarthritis, trauma)
• Neurology, including injuries and other disorders of the peripheral nerve
• Alzheimer’s Disease, Cognitive Impairment, and Dementia
• Pulmonary/Respiratory Diseases
• Urology

Funded Clinical Trials:
FUNDED CLINICAL RESEARCH /GRANTS AND CONTRACTS:

• A Double-Blind, Placebo-Controlled, Randomized Study Comparing the Effects of XXXX (American Ginseng Extract) and Placebo in Naturally-Occurring Respir- atory Illness in Frail Older Adults
• A Study of Anemia in the Nursing Home
• A Multi-Center, Randomized, Double-Blind, Placebo Controlled Trial of Estrogens to Prevent Alzheimer's Disease and Loss of Memory in Women
• Safety and Immunogenicity of Tetanus and Diptheria Toxoids Adsorbed Combined with Component Pertussis (TdcP) Vaccine Compared to Tetanus and Diptheria Toxoids Adsorbed (Td) in Adolescents and Adults 11-64 years of age
• Safety and Immunogenicity of Influenza Virus Vaccine USP Trivalent Types A and B (Zonal Purified Subviron) Fluzone Formula
• Reactogenicity Following Influenza Vaccination by Double Blind Randomized Placebo Controlled Intradermal (ID) Needless Jet Injector (Bioject) Compared to Intramuscular (IM) Injection in Institutionalized Frail Elderly Volunteers.
• A Study to Evaluate the Cell-Mediated Immune Responses of Herpes Zoster Patients Compared to Healthy Subjects Over a Six- Month Period.
• Safety and Immunogenicity of Influenza Virus Vaccine USP Trivalent Types A and B (Zonal Purified Subviron) Fluzone Formula
• Immunogenicity and Safety of Concommitant Administration of Typhoid Vi Vaccine When administered with an Experimental Tetravalent (A,C,Y, and W-135) Meningococcal Diptheria Toxoid Conjugate Vaccine (TetraMenD).
• Comparative Randomized Study of Safety and Immunogenicity of a Non Adjuvanted RSV Vaccine Versus an RSV Vaccine Adjuvanted with Aluminum Phosphate when Administered Concomitantly with a Licensed Influenza Vaccine in High- Risk Adults Greater Than or Equal to 65 Years of age.
• Safety and Immunogenicity of a Recombinant Pneumococcal Surface Protein Vaccine (rPSPV) in Healty Adults 18-45 Years of Age.
• Annual Study of Safety and Immunogenicity of Influenza Virus Vaccine Fluzone Formulation
• Safety and Dose Escalation of a Pneumococcal Surface Protein A (PspA) Vaccine for Streptococcus pneumonia in Adults- 2nd Follow-up to Phase 1
• A Prospective, Open-Label, Multi-center, Two-part study to Investigate Patient Satisfaction With Monthly Dosed XXXX Therapy in Women with Postmenopausal Osteoporosis or Osteopenia Transitioned From Once-Weekly Alendronate or Risendronate
• A Dose-Ranging Placebo-Controlled Study of XXXX at the Doses of 0.5 mg, 2 mg and 8 mg for 12 Weeks in Patients with Mild-to-Moderate Alzheimer's Disease
• Annual Study of Safety and Immunogenicity of Influenza Virus Vaccine Fluzone 31.
• A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Phase 2 Study to Evaluate the Safety and Efficacy of XXXXX in Subjects with Mild to Moderate Alzheimer's Disease.
• A Randomized, Double-Blind, Placebo-Controlled Evaluation of the Effectiveness and Safety of XXXXX in Nursing Home Residents with Moderate to Severe Alzheimer's Disease.
• A prospective, open-label, multi-center, two-part study to investigate patient satisfaction with monthly dosed XXXXX therapy in women with postmenopausal osteoporosis or osteopenia transitioned from once-weekly alendronate or risedronate
• A Randomized, Multicenter, Double-Blind, Placebo-Controlled, 18-Month Study of the Efficacy of XXXXX in Patients with Mild-to-Moderate Dementia of the Alzheimer's Type.
• Extension of A Randomized, Multicenter, Double-Blind, Placebo-Controlled, 18 Month Study of the Efficacy of XXXX in Patients with Mild to Moderate Dementia of the Alzheimer%92s Type.
• A Randomized, Double-Blind, Placebo-Controlled, Efficacy, Safety, and Tolerability Study of XXXXX in the Treatment of Elderly Subjects with Psychosis and Behavioral Disturbances Associated with Dementia of the Alzheimer's Type
• A Double-Blind, Placebo Controlled Study of Adults Undergoing Non-Urgent Coronary Artery Bypass Surgery to Assess Effects of XXXX on Postoperative Cognitive Dysfunction.

Facility Description

Vista Clinical Research is located in the Hampton Roads metropolitan area serving a population of just over 1.5 million. It is conveniently located near Norfolk International Airport and just off a major interstate.

Vista Clinical Research is equipped with:

• Examining Rooms,
• Centrifuge,
• Refrigeration units,
• Phlebotomy Lab,
• Doppler Ultrasound.

We access ancillary services located in our building, including:

• Large ENT practice,
• Cardiology,
• Pulmonary Medicine,
• Internal Medicine,
• Urgent Care Center,
• Occupational Therapy
• Physical Therapy.

Directly adjacent facility with:

• Hospital laboratory service,
• MRI, CT, full xray services,
• Diagnostic cardiology,
• noninvasive vascular lab,
• nuclear medicine,
• pathology laboratory.

Vista Clinical Research also has access to state of the art interactive driving simulators for multiple outcome measures.

Investigator Experience

Vista Clinical Research utilizes a wide network of Principal and Sub-Investigators all board certified in their respective specialties.

The medical director, Ronald Freund, M.D., FACS, is an orthopedic surgeon with 22 years of clinical experience and chief interests in arthritis, neuropathy, sports medicine, geriatrics, metabolism and trauma. He is certified by the American Board of Orthopaedic Surgery, the American Board of Neurological and Orthopaedic Surgery, and an additional certification in upper extremity surgery (CAQSH).

Vice-President for Clinical Research: Barbara Freund, PhD. Dr Freund is an Associate Professor of Medicine at Eastern Virginia Medical School and the Director of the Driving Simulation Laboratory. Dr Freund was a member of the EVMS IRB for 6 years and served as its chairman for 2 years. She has been principal investigator on several complex trials including Alzheimer's studies and co-investigator on numerous other studies including osteoporosis and vaccine efficacy studies. She is nationally recognized as an expert in cognition and driving.

Staff Expertise

Study Conduct:

• Protocol evaluation/ Grant writing and submission;
• Financial/budgetary analysis;
• Site preparation;
• Patient recruitment;
• Screening/scheduling;
• Study performance (including Informed Consent and Adverse Event Collection);
• CRF/source documentation;
• Test article accountability;
• Sponsor Communication;
• Study Closure;
• Quality Assurrance/Auditing.

IRB/Regulatory Issues:

• Investigational drug/device process;
• Institutional Review Board submission;
• Responsibilities and obligations (Good Clinical Practices and Good Laboratory Practices).

Laboratory/Clinical Activities:

• Ensure proper collection, processing of specimens;
• Develop Laboratory Standard Operating Procedures and Quality Assurance Program;
• Communication with Laboratory Director/ Principal Investigator regarding data generated (including statistical analysis);
• Maintain OSHA, CLIA and CAP standards;
• Maintain supplies/ inventory;
• Maintain equipment (calibration and preventative maintenance);
• Recognize common laboratory values and alerts;
• Assure current laboratory certification;
• Perform study-related procedures (e.g., phlebotomy, vital signs, ECG)

Patient Demographics

The Hampton Roads/Tidewater area is the nation's 27th largest metropolitan market with a diverse population of over 1.5 million people.

Other Information

Vista Clinical Research uses both central and local(EVMS) IRB services.

Contact Information

Ronald Freund, M.D.
Medical Director
Vista Clinical Research
816 Independence Blvd, Suite 3B
Virginia Beach, VA 23454
USA
Phone: 757-464-3529
Fax: 757-464-1911
EMail: vistaresearch@cox.net

If you are interested in contacting this center to discuss placing a clinical trial there, please complete and send the E-mail form below. A representative from the research center will then follow up with you.