Center Overview

Cape Cod Research Institute (CCRI) was established in August 2003 as a Not-For-Profit Corporation to further clinical research and medical education in the area of cardiovascular disease. Located in Hyannis Massachusetts, CCRI allows patient access to sophisticated devices, procedures and pharmaceuticals without having to travel to tertiary centers; assuring patients that all level of cardiac care can be offered by the local physicians with how they have come to trust.

CCRI is a fully functioning research facility that is legally independent from the hospitals and the physician practices with which we work. The infrastructure of the Cape Cod Research Institute ensures that Physician Investigators, Industry Sponsors and Subjects who participate in clinical studies have access to legal, ethical, scientific and regulatory expertise. A staff of knowledgeable research nurses and technicians carefully track and maintain patient data. Each clinical trial is carefully analyzed for ethics and patient safety by the staff of CCRI as well as an independent Institutional Review Board.

CCRI serves as the infrastructure to encourage and support its physician scientist and serves as an interface between clinical investigators and sponsors of clinical trials. CCRI provides a high level of clinical trial services to help investigators compete and meet the demands of industrial sponsors. For sponsors, we provide high quality data and reliable, appropriate subject enrollment. We strictly adhere to good clinical practice (GCP).

Services to PIs include:

• Link industry to physicians and support the administration of clinical trials
• Assistance with the IRB application and representation
• Negotiate clinical trial agreements and Contact facilitation
• Preparation and negotiation of budgets
• Assistance in patient recruitment
• Ongoing Data management support and regulatory compliance
• Assistance with strategy and proposal development for corporate-sponsored and investigator-initiated clinical trials

Clinical Research Experience

CCRI has experience in Phase II, Phase III, and Phase IV clinical trial management in both drug and device trials. CCRI has almost exclusive access to the large population of Cape Cod and the Islands, as well as the South Shore area of Massachusetts. We have a large referral base with over 100 area primary care physicians.

CCRI primarily specializes in the area of cardiovascular disease with a focus on the following sub-specialties:

• Interventional Cardiology
• Interventional Radiology
• Arrhythmia/electrophysiology
• Vascular surgery
• Carotid intervention
• Cardiac Imaging
• Congestive Heart Failure
• Hyperlipidemia
• Acute Coronary Syndromes
• Angina
• Hemostasis/Thrombosis
• Acute Myocardial Infarction
• Obesity
• Hypertension

The following are some of the sponsors and that we have worked with to date:

• Abbott Vascular Devices
• Bard Peripheral Vascular, Inc
• Boston Scientific
• E. Lilly & Co.
• FoxHollow
• Cardiovascular Research Foundation
• Impulse Dynamics
• Conor Medsystems, Inc
• TargeGen, Inc
• The Medicines Co.
• Cordis Corporation
• Procter& Gamble Pharmaceuticals
• Alexion Pharmacruticals, Inc
• Coaxia
• Mitsubisishi Pharma Corporation
• Velocimed, Inc
• St. Jude Medical
• Guidant Corporation

Facility Description

We are centrally located in Hyannis, Massachusetts, minutes away from Cape Cod Hospital.

Investigator Experience

Richard Zelman, MD FACC is President and Medical Director of CCRI, with over 15 years clinical research experience. Dr. Zelman serves as the Director of Interventional Cardiology at both Cape Cod and Falmouth Hospital. Dr. Zelman is Board Certified in Interventional Cardiology, with expertise in Critical Care Management and Carotid Stenting.

Philip Dombrowski, MD is the Chief of Interventional Radiology at Cape Cod Hospital and has over 10 years experience in research. Dr. Dombrowski has formed a multidisciplinary center of vascular excellence that includes cardiologists, vascular surgeons and interventional radiologists. His center offers complex cardiac procedures, such as aortic stent grafting. The aim is to create a program that will attract referring physicians and patients with vascular disease from all over Cape Cod and the South Shore.

Peter Friedman, MD PHD FACC is board certified in Cardiovascular Disease and Clinical Cardiac Electrophysiology. Dr. Friedman specializes in Pacemaker implantation, Defibrillator implantation, catheter ablation and cardiac electrophysiology.

Mark Wolfe, MD FACC has over 15 years experience in research. Dr. Wolfe is board certified in Cardiology. Dr. Wolfe expertly performs Trans-esophageal echocardiography, nuclear imaging, stress testing and cardiac catherization.

Staff Expertise

Richard B Zelman, MD FACC President & Medical Director
Richard B Zelman, MD FACC is President and Medical Director of CCRI, with over 15 years clinical research experience. Dr. Zelman serves as the Director of Interventional Cardiology at both Cape Cod and Falmouth Hospital. Dr. Zelman is Board Certified in Interventional Cardiology, with expertise in Critical Care Management and Carotid Stenting.

Carolyn Healy, RN CCRC Clinical Nurse Coordinator
Ms. Healy is an experienced clinical research nurse with over 10 years experience. Ms. Healy coordinates and conducts multiple clinical trials, ranging from Phase I to Phase IV in both the inpatient and outpatient settings and has overseen the management of over 50 clinical trials.

Kerri Ames, Business Operations Manager
Ms. Ames is responsible for administrative decision making; fiscal oversight, implements and enforces office and human resource policies and procedures, workflow priorities and standards.

Patient Demographics

As one of the most respected research facilities in the Cape Cod Area, CCRI is able to draw from the large population of Cape Cod & the Islands as well as the South Shore area of Massachusetts. We offer unique patient demographics. Our patient population is from the age of 18-90 and from multi-ethnicities. With over 100 area primary care physicians, CCRI offers a large referral base.

Contact Information

Richard B. Zelman, MD FACC
Medical Director
Cape Cod Research Institute
Cape Cod Medical Building
40 Quinlan Way, Suite 130
Hyannis, MA 02601
USA
Phone: 508-778-5900
Fax: 508-778-9300
EMail: ccri@caperesearch.org
Web Site: http://www.caperesearch.org

If you are interested in contacting this center to discuss placing a clinical trial there, please complete and send the E-mail form below. A representative from the research center will then follow up with you.