Research Center Profile:
Kaiser Permanente Southern California Clinical Trials
The Southern California Permanente Clinical Trials (SCPCT)
program believes that all research should focus on advancing the
practice of medical care to improve health outcomes. Southern
California Permanente Clinical Trials investigators are practicing
physicians bridging the gap between research and clinical practice.
Typically, research in Kaiser Permanente is aimed at evaluating the
impact at the bedside and using this perspective to develop study
designs that answer meaningful questions. SCPCT clients are able to
recruit study participants from within the Kaiser Foundation Health
Plan's 3.1 million Southern California membership.
Kaiser Permanente (KP) is the largest vertically integrated
private health care delivery system in the United States. The
Permanente Medical Groups of physicians provide prepaid medical
care to nearly 9 million members of the Kaiser Permanente Medical
Care Program. The Permanente Medical Groups represent one of the
oldest Medical Research Organizations in the United States and have
been conducting research into health care intervention and delivery
since the 1950s. Research is important to Kaiser Permanente because
it is not only a part of our organizational mission, but it
provides Kaiser Permanente Health Plan members access to innovative
new technologies and medicines.
SCPCT is a Kaiser Southern California regional resource for
coordinating all aspects of clinical trials services. The SCPCT
staff acts as an interface between investigators, sponsors, and KP
regulatory bodies. From the sponsor's perspective, we help find
investigators appropriate for trials. Once an investigator is
identified, we work with the sponsor and the investigator to
facilitate their application through IRB, finance, and contracting.
We also hire and provide study coordinators and research associates
to facilitate the study.
Kaiser Permanente is the world's largest integrated clinical
research organization. Southern California Permanente Clinical
Trials (SCPCT) combines the clinical expertise of one of the
largest medical groups with a research organization.
In Southern California, over 4,700 physicians take care of over
3 million patients in fourteen geographic areas. With this
resource, SCPCT is capable of conducting any clinical research
project, from the smallest pilot studies to drug trials to outcomes
and quality of life analyses. Our experience stretches from Phase
II to Phase IV and beyond, encompassing post-marketing analyses.
SCPCT conducts studies in more than 26 therapeutic areas: Allergy,
Bio-chemotherapy, Cardiac surgery, Cardiology, Endocrinology,
Gastroenterology, Gynecology oncology, Hepatology, Infections
diseases, Internal medicine, Nephrology, Metabolic genetics,
Neurology, Adult oncology, Pain Management, Pediatric oncology,
Ophthalmology, Plastic surgery, Surgical oncology, Urology,
Pediatrics, and Vascular surgery.
Southern California Permanente Clinical Trials research is
conducted at all 11 strategically located Kaiser Permanente Medical
Centers of Southern California: Baldwin Park, Bellflower, Fontana,
Harbor City/South Bay, Los Angeles, Orange County, Panorama City,
Riverside, San Diego, West Los Angeles, and Woodland Hills.
Our investigators are all practicing physicians to these
specialties, applying state-of-the-art research in their own
practices. Their informed input on study design and interpretation
creates more efficient, practical, and pertinent research. Our
investigators also focus strongly on disseminating research
results, publishing more than 300 articles per year in
peer-reviewed journals. Their effects on patient care and the state
of medicine are felt around the world.
Southern California Permanente Clinical Trials (SCPCT) staff has
experience with all aspects of clinical trials management such as
study coordination, data management, project, human subjects
protection, budget development, and contracting. The Regulatory
Services group was officially formed at SCPCT in 2002. This group
provides support for regulatory processes, filing and maintenance
of investigator-initiated INDs/IDEs, protocol review, new project
consultation, and training. SCPCT also provides site management and
clinical monitoring capabilities for some of our investigators.
SCPCT Site Management assists our investigators with
qualification/selection and site recruitment, investigative site
start-up and training, clinical trial enrollment, site regulatory
compliance, CRF completion, data collection, and query
resolution.
The SCPCT staff include: Azucena Luna, MD, who oversees every
aspect of SCPCT Operations, and Barry Grubs, who coordinates
protocol review and identifies appropriate investigator. In
addition, there are regulatory, IT, nursing and non-nursing
research support staff located in the regional SCPCT office and in
the medical centers.
Kaiser Permanente Southern California (KPSC) provides
comprehensive health care on a pre-paid basis to 3.1 million
residents of Southern California. The population served by the
program is diverse and broadly representative of the population of
Southern California ethnically and in terms of education and
income.
Clinical Trials in SCPCT is supported by the Kaiser Permanente
Southern California Institutional Review Board (KPSC-IRB).
SCPCT investigators use the iMedRIS clinical trial management
tool to help track participant and study activities, research
compliance, and conduct.
Daniel J. Pinion
Clinical Trials Research
Kaiser Permanente Southern California Clinical Trials
100 South Los Robles, 2nd Floor
Pasadena, CA 91101
USA
Phone: 626-564-5667
Fax: 626-564-7872
EMail: Daniel.J.Pinion@kp.org
Web Site: http://www.kp.org/scpct
If you are interested in contacting this center to discuss placing a clinical
trial there, please complete and send the E-mail form below. A representative from
the research center will then follow up with you.
