Clinical Trial Resource Center

Therapeutic Areas

Cardiology/Vascular Diseases
Endocrinology
Gastroenterology
Hepatology (Liver, Pancreatic, Gall Bladder)
Immunology
Musculoskeletal
Nephrology
Neurology
Nutrition and Weight Loss
Orthopedics/Orthopedic Surgery
Psychiatry/Psychology
Urology

Center Overview

Upstate Pharmaceutical Research is a dedicated Phase I-IV research site, founded in 2000. Located in Greenville, SC, Upstate Pharmaceutical Research is very close to Patewood Memorial Hospital and St. Francis Hospital. Upstate Pharmaceutical Research staff has many years of combined research experience. We are dedicated to following Good Clinical Practice Guidelines and meeting all FDA requirements. PI and coordinators are certified by A.C.R.P. Our patients feel we care for them because we believe "patients first," and we continue to work hard, learn, and grow. Our PI is involved in true sense, which makes our center unique.

Upstate Pharmaceutical Research services include:

• Five full-time coordinators submitting documents promptly
• Study Manager software program to include database housing, accounting capabilities and patient tracking
• Patient database of over 20,000
• Referral base of over 12,000 from busy family practices
• The ability to use central IRB’s and prompt submission, less than a week
• Dedicated regulatory person
• Experience with PK, sampling, time points, frequent spirometries, plethysmography, and oxycon bicycle ergometry
• We even work on Saturdays to accommodate our patients
• We have several sub specialists, PI, and sub PI’s include cardiovascular, Ob-Gyn, GI, Psychiatry, Ortho, Podiatry, Neurology, and Dermatology
• Compliance and Retention is our goal

Performance Metrics

Number of Active Patients in the Database: 3000+
Regulatory Submission Turn-Around Time: 2 Week(s)
Average Percent of Total Patients Randomized: 95%
Average Percent of ‘Completed’ Studies that met Enrollment Goals: 99%
EDC Capabilities: Yes

Clinical Research Experience

Since 2000, Upstate Pharmaceutical Research has conducted over 100 studies in the following areas:

• Allergic Rhinitis
• Anticoagulation Studies
• Asthma
• Atrial Fibrillation
• Bladder Disorders
• BPH
• COPD
• Chronic Renal Insufficiency
• Diabetes
• Diabetic insulin inhalers
• Diabetic Nephropathy
• Gout
• Hyperlipidemia
• Hypertension
• Insomnia
• Menopause
• Neuropathy
• Obesity
• Osteoarthritis
• Organic impotence
• Stem cell infusion

Ability to conduct studies in the following indications/areas:
COPD, Asthma, Diabetes, Hyperlipidemia, Carpal tunnel, restless leg syndrome, acid reflux, back pain, constipation, migraines, depression and anxiety, IBS. Specialty areas: pulmonary, cardiology, orthopedic, gynecology, and podiatry studies.

Previous and current sponsors/CRO’s include:

Abbott Actelion Arena AstraZeneca Bayer Boehringer-Ingleheim Bristol Myers Squibb Covance CTMS Depomed Eli Lilly Elixir Forest GlaxoSmithKline Icon Mannkind MedImmune

Merck Mylan Bertek Novartis Omnicare Osiris Parexel Pfizer Pharmanet PPD Sanofi Aventis Sepracor Shionogi Quintiles Schering Plough Takeda Tap UBC

Facility Description

10,000 sq. foot dedicated space Phase I-IV research facility and less than half a mile from Patewood Memorial Hospital: 30 Pointe Circle

• Comfortable lounge areas accommodating patients for all-day studies, including beds and showers
• Patient dining room and catered meals
• 10 private exam rooms
• 4 private offices for coordinators
• 3 private rooms for monitors
• Secure rooms for on-site record storage
• Temperature controlled, secured storage rooms for drugs, separate secure storage for refrigerated drugs
• Patient database and study management on Study Manager software system
• State of the Art Stress Test
• Pulmonary Function Lab with DLCO, body phlethysmography, 6 minute walk, bicycle ergometry
• Full Laboratory with -20 and -70 freezers
• Holter & Event monitors experience
• 24 hour ABP monitors experience
• ECG
• Brand new exercise lab with metabolic bicycle ergometer
• State of the Art Cardiac 2-D echo
• Refrigerated Centrifuge
• Photocopy Machine with Scanning and Faxing CapabilitiesDefibrillation and crash cart
• Defibrillation and crash cart
• Our center has access to MRI, CT, mammogram, and x-ray
• Wireless and Wired Broadband Internet access
• Sputum processing

Investigator Experience

Medical Criteria

Principal Investigator:
Krishna K. Pudi, MD is board certified in internal medicine. He has 16 years total of research experience. Dr. Pudi was the Medical Director of the Hospitalist Program at the Spartanburg Regional Hospital.

Sub-Investigators
Dr. Julian Williams

Dr. Stephen Keiser

Affiliated Investigators
Dr. Gurpreet Maur-Cardiology
Dr. Abbas Mansour-Pulmonary Medicine and Critical Care
Dr. Ravi Chandran-Pulmonary Medicine and Critical Care

Upstate Pharmaceutical Research
(864)255-3540

Staff Expertise

• 5 Experienced Coordinators
• Echo Technician
• Regulatory Document Person
• Extensive Experience creating source documents
• Staff is certified with BCLS-CRC-ACLS
• Experience with infusion treatment

Patient Demographics

Greenville County Population by Gender 2000

Total = 379,616

Male=184,782 (48.7%)

Female=194,834 (51.3%)

Greenville County Population by Race 2000

White Black American Indian & Alaskan Native Asian Native Hawaiian & Pacific Islander Other Two or More Races Total

294,324 69,455 726 5,242 171 5,387 4,311 379,616

77.50% 18.30% 0.20% 1.40% 0.01% 1.40% 1.10%

Upstate Pharmaceutical Research
(864)255-3540

Contact Center

If you are interested in contacting this center to discuss placing a clinical trial there, please complete and send the email form below. A representative from the research center will then follow up with you.

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