Therapeutic Areas

Cardiology/Vascular Diseases
Dermatology
Endocrinology
Gastroenterology
Infections and Infectious Diseases
Internal Medicine
Musculoskeletal
Nutrition and Weight Loss
Otolaryngology (Ear, Nose, Throat)
Psychiatry/Psychology
Pulmonary/Respiratory Diseases
Rheumatology

Center Overview

Castlerock Clinical Research Consultants (CCRC) is a dedicated clinical research site. The site completes specialty, adult, outpatient trials, primarily:

• Internal Medicine
• Cardiology
• Neurology
• Dermatology
• Infectious Disease
• Pulmonary Medicine
• Gastroenterology
• Ear nose and throat
• Metabolic Diseases

The site is dedicated to excellence and has been developed to meet the need for medical and health research intended to produce valuable knowledge for understanding human disease prevention, treatment of illness, and promotion of health.

Clinical Research Experience

The investigators and staff of CCRC have extensive experience in the conduct of clinical trials. Trial experience includes phase II through IV studies specific to cardiology, endocrinology, musculo-skeletal, gastrointestinal, internal medicine, ENT pharmaceutical agents, and pulmonary medicine. CCRC has participated in many precedent setting studies that have helped change Standard of Care Guidelines in the practice of medicine.

Sponsors for which we have experience include Parke-Davis, Pfizer, Roche, Bristol-Myers Squibb, Kos, Smith Kline Beecham, GlaxoSmith Kline, Merck, Schering Plough, Takeda Astra Zeneca, Aventis, Sankyo, Novartis, Lilly and others. CROs we have worked with include Covalent, Covance, Quintiles, PPD, ICON, Omnicare, Integrium, Medpace and others.

Facility Description

Castlerock Clinical Research Consultants offer full service outpatient facilities including:

• 2 fully equipped exam rooms
• Mercury manometers
• ECG
• Treadmill
• Locked, temperature monitored, ambient and refrigerated drug storage
• 2 fully equipped laboratories
• -80° freezer
  -20° freezer
• Locked refrigerator
• 2 Ambient centrifuges
• Refrigerated centrifuge
• 2 Study monitor areas with high speed internet connection
• Dedicated fax and copy machines
• CRF and Regulatory document long term storage space

The research office is adjacent to Saint Francis Health System and is easily accessible via public transportation.

Investigator Experience

All Investigators are board certified in their specialty and manage large, outpatient medical practices. The following Investigators are experienced in the conduct of clinical trials:

• Richard N. Marple, MD, FACP, CPI -Internal Medicine
• Susan B. Marple, RN, MSN, NP, CCRC

Specialty investigators are available, as needed, for consultation on all clinical trials.

Staff Expertise

In 2002 Susan B. Marple MSN, NP, CCRC and Richard N. Marple, MD, FACP, CPI answered the call for excellence in the clinical research industry by organizing an independent site, Castlerock Clinical Research Consultants. All research personnel have completed certification for the following: SafTpak training for the shipment of Dangerous Goods, Shared Care Certification for Blood Pressure Monitoring, BCLS certification, as well as state licensure in their profession.

Richard N. Marple, MD, FACP, CPI Principal Investigator functions as Medical Director for the site. Dr. Marple has many years experience as Medical Director and Principal Investigator as well as having served as a member of the local Institutional Review and Ethics Board. Dr. Marple is certified in clinical research by the Academy of Pharmaceutical Physicians and Investigators.

Susan B. Marple MSN, NP, CCRC,Sub-Investigator is CEO and Clinical Director of Castlerock CRC and has previous experience developing and operationalizing a clinical research site. Ms. Marple has extensive clinical trial experience and has started CCRC as an independent Clinical Research Site dedicated to excellence. Nurse practitioner specialty areas include cardiology and endocrinology. Susan is certified by the Association of Clinical Research Professionals.

Joan Benedict, Regulatory Specialist functions as Administrative Assistant, Office Manager and Regulatory Specialist. Joan completes initial regulatory documents within 48 hours after receipt and maintains impeccable regulatory files.

Tami Dillon, LPN, CRC is full time, Lead Study Coordinator and has many years clinical and research experience.

Julia Miller, RN., full time Study Coordinator, Julia joined Castlerock Clinical Research Consultants in March, 2009 and has proven to be an excellent addition to our coordinator staff.

Patient Demographics

Demographic information indicates that the Tulsa Metropolitan area includes 850,000 residents primarily Caucasian, Hispanic, African American, and Native Americans. Private medical practices of investigators are reflective of the ethnic mix.

Other Information

Castlerock Clinical Research utilizes Central Institutional Review Boards for regulatory compliance.

Currently Enrolling Trials

• High Risk Hyperlipidemia
• Hypertension with Metabolic Syndrome
• Stage III Hypertensioon
• Difficult to treat Hypertension (currently on 3 or more drug therapy)
• Atrial Fibrillation
• Type II Diabetes
• Gout
• Obesity

Contact Center

If you are interested in contacting this center to discuss placing a clinical trial there, please complete and send the email form below. A representative from the research center will then follow up with you.