Articles Published in 2011 Articles | CenterWatch News Online

Articles Published in 2011

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Caliper, Pfizer launch platform for drug safety

Thursday, November 3, 2011 09:02 AM

Caliper Life Sciences, a provider of tools and services for drug
discovery and life sciences research, has launched a new services
offering based on a panel of cellular assays that measure the effects of
drug candidates on functional activity of proteins called kinases involved
in critical cell-signaling pathways. The technology platform and initial
panel of nine assays were developed in collaboration with Pfizer. The new offering, called In-Cell KinaseScreen, is immediately available for compound screening, profiling, and custom assay development services for CDAS' clients, ranging from academia to pharmaceutical companies.

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Sanofi restructues cutting sales jobs

Wednesday, November 2, 2011 01:43 PM

French drugmaker Sanofi has reported it is reorganizing research operations in the U.S. and planning to trim its sales force for the second time in barely a year as it aims to boost efficiency, according to the Associated Press.

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Karyopharm Therapeutics secures $10 million in Seires A2 financing

Wednesday, November 2, 2011 01:29 PM

Karyopharm Therapeutics has completed a $10M Series A2 financing which complements the $20M Series A financing announced one year ago. Both Series A and A2 were lead by Chione. This brings the total raised by the company to approximately $32M since its inception. The funds will be used to expand the planned phase I program, targeted to begin in mid 2012 with Karyopharm's oral selective inhibitors of nuclear export (SINE) for various cancers. The company is also evaluating related transport modulators for use in dermatologic, inflammatory, and viral disorders.

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Potthoff named president, CEO of Theorem Clinical Research

Wednesday, November 2, 2011 01:13 PM

John Potthoff has stepped down as chief operating officer of CRO INC Research to become president and CEO of Theorem Clinical Research, succeeding James Pusey, who now becomes Theorem’s executive chairman to the board of directors.

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Axia Value names Christina managing director

Wednesday, November 2, 2011 01:03 PM

Axia Value Chain has named John Christina managing director of their life sciences and healthcare practice group. In his new role, Christina will lead efforts with global clients in the healthcare and life science industry and be responsible for business development, consulting services, practice development, and service offerings concentrating on alignment of organizational operations with business strategies, supply chain management, and optimization of the value chain.

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Plasticell honored at R&D 100 Awards

Wednesday, November 2, 2011 12:51 PM

For almost 50 years, the R&D 100 Awards have been recognizing the year’s best new high-technology products. Determined by a panel of experts chosen by R&D Magazine, the award is recognition that the selected product is one of the most important innovations of the year. Plasticell's CombiCult was chosen as one of the hundred for 2011, which included only three technologies from the U.K.

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CoreRx selects Xcelodose to enhance product development

Wednesday, November 2, 2011 12:34 PM

CoreRx, a contract development and manufacturing organization, has enhanced its offering by adding an Xcelodose precision powder micro-dosing system to its product development capabilities in response to client requirements for preclinical and early phase clinical GMP supply. The Xcelodose decreases processing time and API use – generating significant cost savings to clients.

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Clinipace names VP, European clinical operations

Wednesday, November 2, 2011 12:17 PM

Clinipace Worldwide has named Andrea Schiefer, Ph.D., vice president of European clinical operations and executive director of pharmacovigilance. In this position, Andrea reports directly to Kurt Pfister, chief executive officer of European operations at Clinipace Worldwide, and is responsible for providing leadership and direction to the project management, clinical monitoring and safety groups within the European clinical operations unit at Clinipace Worldwide.

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Resverlogix begins dosing in phase IIb ASSURE trial

Wednesday, November 2, 2011 11:43 AM

Resverlogix has initiated dosing in ASSURE, a phase IIb clinical trial led by the Cleveland Clinic. ASSURE is a 26-week, multi-center, double-blind, randomized, parallel group, placebo-controlled clinical trial that will assess coronary atherosclerotic plaque changes in response to Resverlogix's lead drug RVX-208 using intravascular ultrasound (IVUS). ASSURE will examine the early effects of RVX-208 induced ApoA-I production on atherosclerotic plaque regression in the setting of patients with coronary artery disease who have a low level of high-density lipoprotein cholesterol (HDL-C). A total of 310 patients are expected to participate in ASSURE of which 77 will receive placebo and 233 will be given 100 mg twice daily of RVX-208.

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Survey: Covance central laboratory services ranks first

Wednesday, November 2, 2011 11:13 AM

Covance central laboratory services ranked first, by a wide margin, in an independent global survey of 550 physician investigators participating in clinical trials. The majority (54%) of the study participants named Covance central laboratory services as their "most preferred" central laboratory, with investigators citing Covance three times more often than the nearest competitor. Investigators also reported having the "best overall relationship" with Covance, rating it 8.4 on a scale of 1 to 10.

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