University of Michigan

Information blocking routine among vendors and health systems

Saturday, July 1, 2017

Using electronic source data in clinical trials can be difficult because of the interoperability between data capture systems and the aversion to change among sponsors and investigators who are used to doing things a certain way. But what if some vendors and health systems purposely block information from being shared? Congress has expressed concerns about this practice in the past, and a recent study says that information blocking is still considered routine among some vendors and health systems.

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Agilis Biotherapeutics expands Commercial, Medical Teams

Tuesday, May 9, 2017

Agilis Biotherapeutics, a biotechnology company advancing innovative gene therapy products for the treatment of rare genetic diseases that affect the central nervous system (CNS), has expanded its commercial and medical teams, hiring Markus Peters, Ph.D., as chief commercial officer; Kirsten Gruis, M.D., as chief medical officer; and Anne Marie Conway, M.H.A, R.N., as vice president, Clinical Operations.

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St. Jude cybersecurity vulnerabilities spark medical device hacking debate

Monday, January 16, 2017

A recent cybersecurity scandal involving St. Jude’s Merlin@home device sparked a renewed discussion within the medical device industry about the best way to address security flaws discovered by independent security experts, sometimes called “white hat” hackers. As medical devices become increasingly vulnerable to cyber attack, the industry has broadly accepted its new responsibility of continuously protecting approved devices from potential security breaches.

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Early-phase trial demonstrates shrinkage in pediatric neural tumors

Tuesday, January 3, 2017

In an early-phase clinical trial of a new oral drug, selumetinib, children with the common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas, tumors of the peripheral nerves, tolerated selumetinib and, in most cases, responded to it with tumor shrinkage. NF1 affects 1 in 3,000 people. The study results appeared Dec. 29, 2016, in the New England Journal of Medicine.

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Johns Hopkins, Salk co-lead $15M bipolar disorder and schizophrenia initiative

Thursday, September 8, 2016

The Johns Hopkins University School of Medicine and the Salk Institute for Biological Studies will co-lead a $15.4 million effort to develop new systems for quickly screening libraries of drugs for potential effectiveness against schizophrenia and bipolar disorder, the National Institute of Mental Health (NIMH) has announced. The consortium, which includes four academic or nonprofit institutions and two industry partners, will be led by Hongjun Song, Ph.D., of Johns Hopkins and Rusty Gage, Ph.D., of Salk.

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AstraZeneca, MedImmune join chronic kidney disease consortium

Friday, February 12, 2016

AstraZeneca and its global biologics research and development arm MedImmune have entered into a collaboration with the University of Michigan and Eli Lilly to identify new therapeutic targets for the treatment of chronic kidney diseases (CKD). The RPC2 consortium (renal precompetitive consortium) will combine extensive clinical and molecular data collected by Professor Matthias Kretzler at the University of Michigan with the R&D expertise of the pharmaceutical industry.

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International diabetes research knowledge portal opens

Thursday, October 8, 2015

Researchers funded by the NIH and the Foundation for the NIH (FNIH) have expanded a recently launched online library, called a knowledge portal, which allows open-access searching of human genetic and clinical information on type 2 diabetes. Individual data will remain confidential. The portal includes information from several major international networks, collected from decades of research.

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