Targacept, Catalyst Biosciences ink merger

Monday, March 9, 2015

Targacept, a biopharma company based in Winston-Salem, N.C., and Catalyst Biosciences, a privately held biopharma company based in South San Francisco, Calif., have agreed to merge. The combined entity, to be named Catalyst Biosciences, is expected to create a financially strong company to harness the catalytic power of engineered human proteases to develop next-generation biopharmaceuticals with improved efficacy and therapeutic index to treat major diseases.

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Targacept initiates phase IIb study of TC-5214

Thursday, May 30, 2013

Targacept, a clinical-stage biopharmaceutical company developing novel neuronal nicotinic receptors (NNR) therapeutics, plans the initiation of a phase IIb clinical study of TC-5214 as a treatment for overactive bladder (OAB). TC-5214 acts potently on alpha3beta4 and other NNRs located in or around the bladder  believed to play a key role in bladder contraction and signaling of the urge to urinate.

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Targacept to reduce workforce, refocus company

Wednesday, April 25, 2012

Targacept, a N.C.-based clinical-stage biopharmaceutical company developing novel NNR Therapeutics, plans to reduce its workforce by 65 employees, approximately 46%, as part of a strategic plan to focus the company’s resources on its clinical programs and select preclinical opportunities.

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