Seattle Children’s Hospital

Seattle Children’s leukemia trial shows 93% complete remission rate

Friday, June 10, 2016

Seattle Children’s has announced that 39 of 42 patients treated in a phase I clinical trial using genetically reprogrammed T cells to treat relapsed or refractory acute lymphoblastic leukemia (ALL) have achieved complete remission, showing no detectable leukemia cells in the most sensitive tests. Patients treated in the trial, known as Pediatric Leukemia Adoptive Therapy-02 (PLAT-02), had less than a 20% chance of survival upon enrollment using current treatments. Seattle Children’s will launch phase II of the trial this month, with the aim to enroll 70 patients in the next year.

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