Tuesday, May 24, 2016
MorphoSys partner Novartis has confirmed that a phase IIb/III study examining bimagrumab (BYM338) in sporadic Inclusion Body Myositis (sIBM) did not meet its primary endpoint. Data are currently being reviewed and will inform decisions on the bimagrumab development program. Ongoing clinical trials are not being discontinued at this time.
MorphoSys, a German-based antibody library technology company, and Immatics Biotechnologies, a German-based clinical-stage biopharmaceutical company, have formed a strategic alliance to generate novel antibody-based therapeutics against multiple proprietary cancer antigens recognized by T cells.
Emergent BioSolutions, a Rockville, Md.-based global specialty biopharmaceutical company, and MorphoSys, a Germany-based provider of therapeutic antibodies, have inked an agreement for the joint development and commercialization of Emergent’s preclinical bi-specific antibody, ES414, targeting prostate cancer. Emergent will receive an upfront payment of $20 million and milestone payments of up to $163 million.
Global biopharma companies MorphoSys and Celgene have agreed to jointly develop MOR202 globally and co-promote it in Europe. MOR202 is a fully human monoclonal antibody targeting CD38 to treat patients with multiple myeloma and certain leukemias. It currently is being evaluated in a phase I/IIa trial in patients with relapsed/refractory myeloma. The companies will collaborate on the development of MOR202 in multiple myeloma and other indications and share costs.
MorphoSys, a biotechnology company focused on fully human antibodies, and Heptares Therapeutics, a developer of new medicines targeting G protein-coupled receptors (GPCRs), have signed an agreement to discover novel antibody therapeutics targeting GPCRs—membrane proteins involved in a broad range of biological processes and diseases.