Axovant Sciences appoints Dr. David Hung CEO, Marion McCourt as president and COO

Tuesday, April 18, 2017

Axovant Sciences, a clinical stage biopharmaceutical company focused on the treatment of dementia, announced that David Hung, M.D., has been named chief executive officer of Axovant Sciences, effective April 7, 2017. Dr. Hung, who also joined Axovant’s board of directors, succeeds founding chief executive officer Vivek Ramaswamy. Ramaswamy will continue to serve on Axovant’s board of directors and will lead parent company and majority owner Roivant Sciences as its full-time chief executive officer.

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Pfizer to acquire Medivation for $14B

Monday, August 22, 2016

Pfizer and Medivation have entered into a definitive merger agreement under which Pfizer will acquire Medivation, a biopharmaceutical company focused on developing and commercializing small molecules for oncology, for $81.50 a share in cash for a total enterprise value of approximately $14 billion.

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Exelixis adds top personnel

Monday, September 28, 2015

Exelixis has announced three high-level appointments as the company prepares for the potential commercialization of its lead compound, cabozantinib, for the treatment of advanced renal cell carcinoma (RCC) following positive results from the METEOR pivotal phase III trial. William Berg, M.D., has joined the company as senior vice president of medical affairs, Jonathan Berndt as vice president of sales, and Gregg Bernier as vice president of marketing.

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Enzalutamide, bicalutamide demonstrate positive results in Strive trial

Thursday, April 2, 2015

Astellas Pharma and Medivation has announced topline results from the phase II STRIVE trial comparing enzalutamide with bicalutamide in a study population of men with non-metastatic or metastatic castration-resistant prostate cancer. The study achieved its primary endpoint demonstrating a statistically significant increase in progression-free survival (PFS) for enzalutamide compared with bicalutamide (Hazard Ratio = 0.24; 95% Confidence Interval, 0.18-0.32; p<0.0001). Median PFS was 19.4 months in the enzalutamide group compared with 5.7 months in the bicalutamide group.

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Pfizer and Medivation reveal results from phase 3 trial of Dimebon

Monday, April 11, 2011

Pfizer and Medivation reported results from the phase III HORIZON trial of the investigational drug dimebon (latrepirdine) in patients with Huntington disease. Dimebon did not achieve statistical significance for either of the co-primary endpoints, the Mini-Mental State Examination (MMSE), which measures cognition (p=0.39), or the Clinician’s Interview-Based Impression of Change, plus caregiver input (CIBIC-plus), which measures global function (p=0.84).

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